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Ikeda Tsuyoshi
Department SOJO UNIVERSITY Department of Pharmaceutical Sciences, FACULTY OF PHARMACEUTICAL SCIENCES /(DC)Division of Pharmaceutical Sciences, Position |
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| Language | English |
| Publication Date | 2010/07 |
| Type | |
| Peer Review | Peer reviewed |
| Title | Onionin A from Allium cepa inhibits macrophage activation. |
| Contribution Type | |
| Journal | Journal of natural products |
| Journal Type | Another Country |
| Volume, Issue, Page | 73(7),pp.1306-8 |
| Author and coauthor | El-Aasr Mona, Fujiwara Yukio, Takeya Motohiro, Ikeda Tsuyoshi, Tsukamoto Sachiko, Ono Masateru, Nakano Daisuke, Okawa Masafumi, Kinjo Junei, Yoshimitsu Hitoshi, Nohara Toshihiro |
| Details | Onionin A (1), a new, stable, sulfur-containing compound, was isolated from acetone extracts of bulbs of onion (Allium cepa), and its structure was characterized as 3,4-dimethyl-5-(1E-propenyl)-tetrahydrothiophen-2-sulfoxide-S-oxide, on the basis of the results of spectroscopic analysis. This compound showed the potential to suppress tumor-cell proliferation by inhibiting the polarization of M2 alternatively activated macrophages. |
| DOI | 10.1021/np100105u |
| ISSN | 1520-6025 |
| PMID | 20597533 |