イケダ ツヨシ   Ikeda Tsuyoshi
  池田 剛
   所属   崇城大学  薬学部 薬学科
   崇城大学大学院  薬学研究科 薬学専攻
   職種   教授
言語種別 英語
発行・発表の年月 2008/07
形態種別 原著論文
査読 査読有り
標題 Mechanism for conversion of spirosolane derivative into pregnane.
執筆形態 共著
掲載誌名 Chemical & pharmaceutical bulletin
掲載区分国外
巻・号・頁 56(7),pp.1015-7
著者・共著者 Nohara Toshihiro, Okamoto Kahori, Matsushita Sayaka, Fujiwara Yukio, Ikeda Tsuyoshi, Miyashita Hiroyuki, Ono Masateru, Yoshimitsu Hitoshi, Kansui Hisako, Kunieda Takehisa
概要 Previously, we reported an interesting reaction by which esculeogenin A [(5alpha,22S,23S,25S)-3beta,23,27-trihydroxyspirosolane], a sapogenol of tomato-saponin, esculeoside A, was easily converted into a pregnane derivative, 5alpha-pregn-16-en-3beta-ol-20-one, merely by refluxing with pyridine and water. Its chemical mechanism including air oxidation is here described.
DOI 10.1248/cpb.56.1015
ISSN 0009-2363
PMID 18591823