Ikeda Tsuyoshi
   Department   SOJO UNIVERSITY  Department of Pharmaceutical Sciences, FACULTY OF PHARMACEUTICAL SCIENCES
     /(DC)Division of Pharmaceutical Sciences,
Language English
Publication Date 2008/07
Peer Review Peer reviewed
Title Conversion of esculeoside A into esculeogenin B.
Contribution Type
Journal Chemical & pharmaceutical bulletin
Journal TypeAnother Country
Volume, Issue, Page 56(7),pp.926-9
Author and coauthor Aasr Mona El, Oshiro Yukino, Fujiwara Yukio, Miyashita Hiroyuki, Ikeda Tsuyoshi, Ono Masateru, Yoshimitsu Hitoshi, Nohara Toshihiro
Details Conversion of the spirosolane-type glycoside, esculeoside A, a major component contained in the ripe tomato Lycopersicon esculentum fruits, into a solanocapsine-type sapogenol, esculeogenin B-2, (5alpha,22S,23R,25S)-22,26-epimino-16beta,23-epoxy-3beta,23,27-trihydroxycholestane, and esculeogenin B-1, (5alpha,22R,23S,25S)-22,26-epimino-16beta,23-epoxy-3beta,23,27-trihydroxycholestane, which are rare naturally occurring compounds was attained by acid hydrolysis with 2 N HCl in dioxane and water (1 : 1).
DOI 10.1248/cpb.56.926
ISSN 0009-2363
PMID 18591803