スギウラ マサハル   Sugiura Masaharu
  杉浦 正晴
   所属   崇城大学  薬学部 薬学科
   崇城大学大学院  薬学研究科 薬学専攻
   職種   教授
言語種別 英語
発行・発表の年月 2001/06
形態種別 原著論文
査読 査読有り
標題 A ligand-accelerated chiral Lewis acid catalyst in asymmetric Michael addition of thiols to α,β-unsaturated carbonyls
執筆形態 共著
掲載誌名 Synlett
掲載区分国外
巻・号・頁 pp.983-985
著者・共著者 S. Kobayashi, C. Ogawa, M. Kawamura, M. Sugiura
概要 A novel chiral hafnium catalyst, which was readily prepared from Hf(OTf)4 and chiral ligand 1, has been developed in asymmetric Michael reactions of thiols with 3-(2-alkenoyl)-2-oxazolidinones, affording the corresponding adducts in high yields and enantiomeric excesses. Although chiral Lewis acids are less reactive than their original Lewis acids in many cases, ligand-acceleration has been demonstrated in this asymmetric Michael addition reaction.
ISSN 09365214
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