スギウラ マサハル   Sugiura Masaharu
  杉浦 正晴
   所属   崇城大学  薬学部 薬学科
   崇城大学大学院  薬学研究科 薬学専攻
   職種   教授
言語種別 英語
発行・発表の年月 2006/02
形態種別 原著論文
査読 査読有り
標題 Highly selective preparation of allenic and homopropargylic hydrazides through regiospecific addition of propargyltrichlorosilane and allenyltrichlorosilane to various types of N-acylhydrazones
執筆形態 共著
掲載誌名 Advanced Synthesis and Catalysis
掲載区分国外
巻・号・頁 348,pp.323-329
著者・共著者 Uwe Schneider, Masaharu Sugiura, Shu Kobayashi
概要 The highly selective preparation of various types of allenic and homopropargylic hydrazides through regiospecific allenylation and propargylation of the corresponding N-acylhydrazones is reported. These carbon-carbon bond-forming reactions employing in situ prepared propargyl- and allenyltrichlorosilanes proceed smoothly in N,N-dimethylformamide (DMF) without any metal catalysis (neutral Lewis base activation of nucleophiles). The use of Hünig's base as an additive is beneficial in terms of chemical yields. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.
DOI 10.1002/adsc.200505379
ISSN 16154150
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