スギウラ マサハル   Sugiura Masaharu
  杉浦 正晴
   所属   崇城大学  薬学部 薬学科
   崇城大学大学院  薬学研究科 薬学専攻
   職種   教授
言語種別 英語
発行・発表の年月 1992/12
形態種別 原著論文
査読 査読有り
標題 The highly regioselective carbonylation of vinylsilanes
執筆形態 共著
掲載誌名 Journal of Organic Chemistry
掲載区分国外
巻・号・頁 57,pp.4189-4194
著者・共著者 Ryo Takeuchi, Naomi Ishii, Masaharu Sugiura, Nobuhiro Sato
概要 The hydroesterification of vinylsilanes, catalyzed by transition-metal complexes, afforded both β-silyl esters 2 and α-silyl esters 3 in high yield. The Pd(II) complex-catalyzed reaction showed high β-regioselectivity, whereas the Co2(CO)8-catalyzed reaction showed high α-regioselectivity. Vinylsilanes which bore trialkyl-, diphenylmethyl-, dimethylethoxy-, trimethoxy-, diphenylfluoro-, and difluorophenylsilyl groups were regioselectively, and some cases regiospecifically, hydroesterified. Pd(II) complexes were also shown to be effective catalysts of the hydrocarboxylation of vinylsilanes. Hydrocarboxylation was β-regiospecific and gave excellent yields of β-silyl carboxylic acids. Reasonable mechanisms for the reactions are described. © 1992 American Chemical Society.
DOI 10.1021/jo00041a025
ISSN 00223263
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