■ Book and thesis
1.
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2022
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Article
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Effect of an intermolecular disulfide bond introduced into the first loop of CH1 domain of Adalimumab Fab on thermal stability and antigen-binding activity J. Biochem. 172(1),pp.49-56 (Collaboration)
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2.
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2021
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Article
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A comprehensive analysis of novel disulfide bond introduction site into the constant domain of human Fab. Sci. Rep. 11(1),pp.12937 (Collaboration)
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3.
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2021
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Article
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Glycosylation decreases aggregation and immunogenicity of adalimumab Fab secreted from Pichia pastoris. J. Biochem. 169(4),pp.435-443 (Collaboration)
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4.
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2020
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Article
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C-terminal cysteine PEGylation of adalimumab Fab with an engineered interchain SS bond. Biol. Pharm. Bull. 43(3),pp.418-423 (Collaboration)
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5.
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2019
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Article
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Alternative mRNA Splicing in Three Venom Families Underlying a Possible Production of Divergent Venom Proteins of the Habu Snake, Protobothrops flavoviridis. Toxins (Basel) (Collaboration)
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6.
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2018
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Article
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The habu genome reveals accelerated evolution of
venom protein genes. Sci Rep. 8(1) (Collaboration)
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7.
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2018
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Article
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Introduction of a glycosylation site in the constant region decreases the aggregation of adalimumab Fab. Biochem. Biophys. Res. Commun. 503(2),pp.752-756 (Collaboration)
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8.
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2017
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Article
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A novel engineered interchain disulfide bond in the constant region enhances the thermostability of adalimumab Fab. Biochem. Biophys. Res. Commun. 495(1),pp.7-11 (Collaboration)
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9.
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2016
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Article
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Relationship between the magnitude of IgE production in mice and conformational stability of the house dust mite allergen, Der p 2. Biochim Biophys Acta. 1860(10),pp.2279-2284 (Collaboration)
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10.
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2014
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Article
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Epithelium specific ETS transcription factor, ESE-3, of Protobothrops flavoviridis snake venom gland transactivates the promoters of venom phospholipase A2 isozyme genes. Toxicon 92,pp.133-139 (Collaboration)
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11.
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2014
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Article
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Discovery of a novel vascular endothelial growth factor (VEGF) with no affinity to heparin in Gloydius tsushimaensis venom. Toxicon 86,pp.107-115 (Collaboration)
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12.
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2011
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Article
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A [Lys49] phospholipase A2 from Protobothrops flavoviridis venom induces caspase-independent apoptotic cell death accompanied by rapid plasma-membrane rupture in human leukemia cells. Biosci. Biotechnol. Biochem. 75,pp.864-870 (Collaboration)
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■ Academic background
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■ Home Page
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■ Present specialized field
Clinical pharmacy, Pharmaceutical analytical chemistry and physicochemistry
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