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1.
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2023/02
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論文
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The G protein-coupled receptor ligand apelin-13 ameliorates skeletal muscle atrophy induced by chronic kidney disease. Journal of cachexia, sarcopenia and muscle 14(1),pp.553-564 （共著）
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2.
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2022/12
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論文
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Recent topics and advanced therapies in chronic granulomatous disease. Human cell （共著）
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3.
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2022/08
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論文
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Treatment with Polyethylene Glycol-Conjugated Fungal D-Amino Acid Oxidase Reduces Lung Inflammation in a Mouse Model of Chronic Granulomatous Disease. Inflammation 45(4),pp.1668-1679 （共著）
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4.
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2021/05
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論文
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De novo filament formation by human hair keratins K85 and K35 follows a filament development pattern distinct from cytokeratin filament networks. FEBS Open Bio 11(5),pp.1299-1312 （共著）
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5.
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2021/09
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論文
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Acid-responsive HPMA copolymer-bradykinin conjugate enhances tumor-targeted delivery of nanomedicine J Control Release 337,pp.546-556 （共著）
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6.
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2021/01
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論文
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Preparation of enzymatically highly active pegylated-D-amino acid oxidase and its application to antitumor therapy. Curr Drug Deliv （共著）
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7.
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2020
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論文
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Development of Tumor-targeting Antitumor Agents Based on Polymer Effect] Yakugaku Zasshi 140(10),1243-1249頁 （単著）
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8.
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2020/05
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論文
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Efficient Anticancer Drug Delivery for Pancreatic Cancer Treatment Utilizing Supramolecular Polyethylene-Glycosylated Bromelain ACS Applied Bio Materials 3(5),pp.3005-3014 （共著）
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9.
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2020/04
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論文
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Highly effective anti-tumor nanomedicines based on HPMA copolymer conjugates with pirarubicin prepared by controlled RAFT polymerization. Acta Biomater 106,pp.256-266 （共著）
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10.
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2019/07
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論文
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Superior Penetration and Cytotoxicity of HPMA Copolymer Conjugates of Pirarubicin in Tumor Cell Spheroid. Molecular Pharmaceutics （共著）
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11.
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2019/05
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論文
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In vivo Efficacy and Safety Evaluation of Lactosyl-β-cyclodextrin as a Therapeutic Agent for Hepatomegaly in Niemann-Pick Type C Disease. Nanomaterials 9(5) （共著）
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12.
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2018/05
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論文
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The role of vimentin in the tumor marker Nup88-dependent multinucleated phenotype. 18(1),pp.519 （共著）
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13.
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2018
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論文
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Preparation and in Vitro Analysis of Human Serum Albumin Nanoparticles Loaded with Anthracycline Derivatives. Chem Pharm Bull (Tokyo). 66(4),pp.382-390 （共著）
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14.
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2017/10
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論文
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Comparison of the pharmacological and biological properties of HPMA copolymer-pirarubicin conjugates: A single-chain copolymer conjugate and its biodegradable tandem-diblock copolymer conjugate. Eur J Pharm Sci. 106,pp.10-19 （共著）
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15.
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2017/09
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論文
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Improved anticancer effects of albumin-bound paclitaxel nanoparticle via augmentation of EPR effect and albumin-protein interactions using S-nitrosated human serum albumin dimer. Biomaterials. 140,pp.162-169 （共著）
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16.
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2017/04
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論文
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Hyaluronic Acid-zinc Protoporphyrin IX Conjugates for Photodynamic Antitumor Therapy Journal of Nanomedicine & Nanotechnology （共著）
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17.
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2016/12
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論文
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Pronounced Cellular Uptake of Pirarubicin versus That of Other Anthracyclines: Comparison of HPMA Copolymer Conjugates of Pirarubicin and Doxorubicin. Mol Pharm. 13(12),pp.4106-4115 （共著）
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18.
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2016/05
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論文
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Missile-Type Tumor-Targeting Polymer Drug, P-THP, Seeks Tumors via Three Different Steps Based on the EPR Effect 癌と化学療法 43(5),549-557頁 （共著）
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19.
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2016/04
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論文
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N-acetyl-L-methionine is a superior protectant of human serum albumin against post-translational oxidation as compared to N-acetyl-L-tryptophan. Biochem Biophys Rep. 6,pp.266-274 （共著）
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20.
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2016/02
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論文
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pH-sensitive polymeric cisplatin-ion complex with styrene-maleic acid copolymer exhibits tumor-selective drug delivery and antitumor activity as a result of the enhanced permeability and retention effect Colloids Surf B Biointerfaces 138,pp.128-137 （共著）
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21.
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2015
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論文
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HPMA Copolymer-Conjugated Pirarubicin in Multimodal Treatment of a Patient with Stage IV Prostate Cancer and Extensive Lung and Bone Metastases. Target Oncol （共著）
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22.
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2015/08
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論文
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S-Nitrosated human serum albumin dimer as novel nano-EPR enhancer applied to macromolecular anti-tumor drugs such as micelles and liposomes. J Control Release 217,pp.1-9 （共著）
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23.
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2015/03
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論文
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Synthesis and therapeutic effect of styrene-maleic acid copolymer-conjugated pirarubicin. Cancer Sci 106(3),pp.270-278 （共著）
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24.
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2015/02
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論文
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Comparison between linear and star-like HPMA conjugated pirarubicin (THP) in pharmacokinetics and antitumor activity in tumor bearing mice. Eur J Pharm Biopharm 90,pp.90-96 （共著）
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25.
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2015/01
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論文
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Development of next-generation macromolecular drugs based on the EPR effect: challenges and pitfalls. Expert Opin Drug Deliv 12(1),pp.53-64 （共著）
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26.
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2015/03
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論文
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Photodynamic therapy and imaging based on tumor-targeted nanoprobe, polymer-conjugated zinc protoporphyrin Future Science OA （共著）
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27.
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2015/01
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論文
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Effect of different chemical bonds in pegylation of zinc protoporphyrin that affects drug release, intracellular uptake, and therapeutic effect in the tumor Eur J Pharm Biopharm 89,pp.259-270 （共著）
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28.
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2014/10
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論文
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Enhanced bacterial tumor delivery by modulating the EPR effect and therapeutic potential of Lactobacillus casei J Pharm Sci 103(10),pp.3235-3243 （共著）
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29.
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2014/08
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論文
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Styrene-maleic acid copolymer-encapsulated CORM2, a water-soluble carbon monoxide (CO) donor with a constant CO-releasing property, exhibits therapeutic potential for inflammatory bowel disease. J Control Release 187,pp.14-21 （共著）
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30.
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2014/06
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論文
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EPR効果に基づくポリマー抗癌剤の腫瘍デリバリー －微小癌の検出・治療を目的としたセラノスティック薬剤の開発－ 化学工業 65,50頁 （共著）
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31.
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2014/01
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論文
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Two step mechanisms of tumor selective delivery of N-(2-hydroxypropyl)methacrylamide copolymer conjugated with pirarubicin via an acid-cleavable linkage. J Control Release 174,pp.81-87 （共著）
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32.
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2013/12
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論文
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Protection from inflammatory bowel disease and colitis-associated carcinogenesis with
4-vinyl-2,6-dimethoxyphenol (canolol) involve suppression of oxidative stress and inflammatory
cytokines. Carcinogenesis 34,pp.2833-2841 （共著）
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33.
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2013
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論文
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The EPR effect for macromolecular drug delivery to solid tumors: improvement of tumor uptake,
lowering of systemic toxicity, and distinct tumor imaging in vivo Adv Drug Deliver Rev 65,71-79頁 （共著）
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34.
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2013
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論文
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Micelles of zinc protoporphyrin conjugated to N-(2-hydroxypropyl)methacrylamide (HPMA)
copolymer for imaging and light-induced antitumor effects in vivo J Control Release 165,191-198頁 （共著）
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35.
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2013
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論文
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Characterization of Carotenoid Fatty Acid Esters from the Peels of the Persimmon Diospyros
kaki Chem Pharm Bull (Tokyo) 61,pp.666-669 （共著）
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36.
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2013
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著書
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Cancer Chemotherapy Fundamentals of Pharmaceutical Nanoscience pp.401-427 （共著）
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37.
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2013/10
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論文
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PEG化製剤に光明：ABC現象は回避できるか？ ファルマシア 49(10) （単著）
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38.
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2012
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論文
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Protective Role of D -Amino Acid Oxidase Against Staphylococcus aureus Infection. Infect Immun 80,pp.1546-1553 （共著）
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39.
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2012
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論文
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Pegylated D -amino acid oxidase restores bactericidal activity of neutrophils in chronic
granulomatous disease via hypochlorite Exp Biol Med 237,pp.703-708 （共著）
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40.
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2012
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論文
|
HSP32 (HO-1) inhibitor, copoly(styrene-maleic acid)-zinc protoporphyrin IX, a water-soluble
micelle as anticancer agent: In vitro and in vivo anticancer effect. Eur. J. Pharm. Biopharm 81,pp.540-547 （共著）
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41.
|
2012
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論文
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Carbon monoxide, generated by heme oxygenase-1, mediates the enhanced permeability and
retention effect in solid tumors Cancer Sci 103,pp.535-541 （共著）
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42.
|
2011
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論文
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Therapeutic potential of pegylated hemin for reactive oxygen species-related diseases via
induction of heme oxygenase-1: results from a rat hepatic ischemia/reperfusion injury model. J Pharmacol Exp Ther 339,pp.779-789 （共著）
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43.
|
2011
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論文
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The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect Adv Drug Deliv Rev 63,pp.136-151 （共著）
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44.
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2011
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論文
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Intracellular uptake and behavior of two types zinc protoporphyrin (ZnPP) micelles, SMA-ZnPP and PEG-ZnPP as anticancer agents; unique intracellular disintegration of SMA micelles. J Control Release 155,pp.367-375 （共著）
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45.
|
2011
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論文
|
4-Amino-6-hydroxypyrazolo [3,4-d]pyrimidine (AHPP) conjugated PEG micelles : water soluble
polymeric xanthine oxidase inhibitor. J Drug Target 19,pp.954-966 （共著）
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46.
|
2009
|
論文
|
SMA-copolymer conjugate of AHPP: a polymeric inhibitor of xanthine oxidase with potential
antihypertensive effect. J Control Release 135,pp.211-217 （共著）
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47.
|
2008
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論文
|
Targeting of heat shock protein 32 (Hsp32)/heme oxygenase-1 (HO-1) in leukemic cells in
chronic myeloid leukemia: a novel approach to overcome resistance against imatinib. Blood 111,pp.2200-2210 （共著）
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48.
|
2008
|
論文
|
Oxystress inducing antitumor therapeutics via tumor-targeted delivery of PEG-conjugated
D-amino acid oxidase. Int J Cancer 122,pp.1135-1144 （共著）
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49.
|
2007
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論文
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Tumor-targeted induction of oxystress for cancer therapy. J Drug Target 15,pp.475-486 （共著）
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50.
|
2006
|
論文
|
SUMO down-regulates the activity of Elf4/myeloid Elf-1-like factor. Biochem Biophys Res Commun 348,pp.880-888 （共著）
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51.
|
2005
|
論文
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SUMO コードの謎を解く 実験医学 23,1229-1234頁 （共著）
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52.
|
2005
|
論文
|
Sp1-dependent regulation of Myeloid Elf-1 like factor in human epithelial cells. FEBS Lett 579,pp.2811-2816 （共著）
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5件表示
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全件表示(52件)
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