教員情報 - 江﨑　加代子

エサキ　カヨコ Esaki Kayoko
江﨑　加代子

所属生物生命学部生物生命学科

職種准教授

著書・論文歴
1.	2024/09	論文	精神神経疾患と脂質代謝～スフィンゴ脂質をターゲットとした新たな治療戦略の可能性～ DOJIN NEWS 190 (単著)
2.	2024/04	論文	SPTLC2 variants are associated with early-onset ALS and FTD due to aberrant sphingolipid synthesis. Ann Clin Transl Neurol . 11 (4),946-957頁 (共著)
3.	2023/10	論文	Impairment of serine transport across the blood–brain barrier by deletion of Slc38a5 causes developmental delay and motor dysfunction. Proc Natl Acad Sci U S A 120 (42),e2302780120 (共著)
4.	2021/09	論文	Hepatocyte-Specific Phgdh-Deficient Mice Culminate in Mild Obesity, Insulin Resistance, and Enhanced Vulnerability to Protein Starvation. Nutrients. 13 (10),3468 (共著)
5.	2021/01	論文	Lipid Pathology of the Corpus Callosum in Schizophrenia and the Potential Role of Abnormal Gene Regulatory Networks with Reduced Microglial Marker Expression. Cereb. Cortex. 31 (1),448-462頁 (共著)
6.	2020/04	論文	Evidence for Altered Metabolism of Sphingosine-1-Phosphate in the Corpus Callosum of Patients with Schizophrenia. Schizophr. Bull. 46 (5),1172-1181頁 (共著)
7.	2020/03	論文	統合失調症患者死後脳の脳梁におけるスフィンゴ脂質代謝変化脂質栄養学 29 (1),7-14頁 (共著)
8.	2019/06	論文	Investigation of betaine as a novel psychotherapeutic for schizophrenia. EBioMedicine. 45,432-446頁 (共著)
9.	2018/09	論文	The ASCT1 (Slc1a4) Transporter is a Physiologic Regulator of Brain D-Serine and Neurodevelopment. Proc. Natl. Acad. Sci. USA. 115 (38),9628-9633頁 (共著)
10.	2016/03	論文	Adaptive response to L-serine deficiency is mediated by p38 MAPK activation via 1-deoxysphinganine in normal fibroblasts. FEBS Open Bio. 6 (4),303-316頁 (共著)
11.	2016/02	論文	L-セリン欠乏は異常スフィンゴ脂質を含む脂肪体の形成を誘導するアミノ酸研究 9 (2),87-89頁 (共著)
12.	2015/04	論文	L-Serine deficiency elicits intracellular accumulation of cytotoxic deoxy-sphingolipids and lipid body formation. J. Biol. Chem. 290 (23),14595-14609頁 (共著)
13.	2014/10	論文	Exon resequencing of H3K9 methyltransferase complex genes, EHMT1, EHMT2 and WIZ, in Japanese autism subjects. Molecular Autism 5 (1),49 (共著)
14.	2014/06	論文	個体発生と高次機能制御におけるde novoセリン合成の必須性生化学 86 (3),372-381頁 (共著)
15.	2013/04	論文	Increased tyrosine in the brain and serum of mice by orally administering dipeptide SY. Biosci. Biotech. Biochem. 77 (4),847-849頁 (共著)
16.	2013/03	論文	大豆たん白質由来ジペプチドが中枢神経系に及ぼす作用の神経化学的評価大豆たん白質研究 15 (33),79-84頁 (共著)
17.	2013/02	論文	L-serine deficiency caused by genetic Phgdh deletion leads to robust induction of 4E-BP1 and subsequent repression of translation initiation in the developing central nervous system. FEBS J. 280 (6),1502-1517頁 (共著)
18.	2013/02	論文	Deficiency of Schnurri-2, an MHC Enhancer Binding Protein, Induces Mild Chronic Inflammation in the Brain and Confers Molecular, Neuronal, and Behavioral Phenotypes Related to Schizophrenia. Neuropsychopharmacology 38 (8),1409-1425頁 (共著)
19.	2011/11	論文	Soy peptide ingestion increases neuroactive amino acids in the brain of wild-type and genetically engineered serine-deficient mice. J. Nutr. Food Sci. 1 (4),109 (共著)
20.	2010/12	論文	Brain-specific Phgdh deletion reveals a pivotal role for L-serine biosynthesis in controlling the level of D-serine, an N-methyl-D-aspartate receptor co-agonist, in adult brain. J. Biol. Chem. 285 (53),41380-41390頁 (共著)