教員情報 - 月川　健士

ツキガワ　ケンジ Tsukigawa Kenji
月川　健士

所属薬学部薬学科

職種講師

著書・論文歴
1.	2026	論文	Mechanistic Insights into pH-Responsive Drug Release and Antitumor Effects of an Albumin-Pirarubicin Conjugate. Pharmaceutical research (共著)
2.	2026/05	論文	Antitumor efficacy and reduced systemic toxicity of palmitic acid-modified pirarubicin nanoparticles in mice Cancer Chemotherapy and Pharmacology (共著)
3.	2026/03	論文	Caspase-Independent Cell Death Induced by a Nitric Oxide Donor Derived from Valproic Acid in Human Pancreatic Cancer Cells Biological and Pharmaceutical Bulletin (共著)
4.	2026/01	論文	Preparation and evaluation of hydrophobin-pirarubicin glucosamine-containing nanoparticles as an anticancer formulation International Journal of Biological Macromolecules,150460-150460頁 (共著)
5.	2025/12	論文	Secreted protein acidic and rich in cysteine-guided biomimetic delivery of nano-antioxidants reverses muscle atrophy in a mouse model of sarcopenia. Journal of controlled release 391,114567-114567頁 (共著)
6.	2025/08	論文	Insights into the renal protective effects of 7-phenylheptanoic acid in chronic kidney disease mice: modulation of indoxyl sulfate production and gut microbiome homeostasis Drug Metabolism and Disposition,100149-100149頁 (共著)
7.	2025/02	論文	Development of Tumor-targeting Drug Delivery Systems Based on an Understanding of Polymer Characteristics and the Tumor-specific Environment YAKUGAKU ZASSHI (単著)
8.	2024/11	論文	Ibuprofen‑derived nitric oxide donors with a high affinity to human serum albumin induce cell death in pancreatic cancer cells through a non‑caspase 3/7‑mediated pathway. Biomedical reports 21 (5),159-159頁 (共著)
9.	2024/09	論文	Novel Diclofenac-NO Donor With High Affinity for Human Serum Albumin Induces Endoplasmic Reticulum Stress-mediated Cell Death in Human Pancreatic Cancer Cells. Anticancer research 44 (9),3793-3798頁 (共著)
10.	2024/07	論文	7-Phenylheptanoic Acid-Hydroxypropyl β-Cyclodextrin Complex Slows the Progression of Renal Failure in Adenine-Induced Chronic Kidney Disease Mice Toxins (共著)
11.	2024/02	論文	Possible Involvement of Protein Binding Inhibition in Changes in Dexmedetomidine Concentration in Extracorporeal Circuits during Midazolam Use. Biological & pharmaceutical bulletin 47 (2),389-393頁 (共著)
12.	2024/01	論文	Preparation and in Vitro Characterization of Fatty-Acid Modified Pirarubicin Nanosuspensions Stabilized by Albumin. Chemical & pharmaceutical bulletin 72 (1),21-27頁 (共著)
13.	2024/01	論文	Development of α-Cyclodextrin-Based Orally Disintegrating Tablets for 4-Phenylbutyrate. Pharmaceutics 16 (1) (共著)
14.	2023/10	論文	Study of the Structural Chemistry of the Inclusion Complexation of 4-Phenylbutyrate and Related Compounds with Cyclodextrins in Solution: Differences in Inclusion Mode with Cavity Size Dependency. International journal of molecular sciences 24 (20) (共著)
15.	2023/09	論文	Extracellular and intracellular productions of lysophosphatidic acids and cyclic phosphatidic acids by lysophospholipase D from exogenously added lysophosphatidylcholines to cultured NRK52E cells. Biochimica et biophysica acta. Molecular and cell biology of lipids 1868 (9),159349 (共著)
16.	2023/02	論文	Study of the inclusion complexes formed between 4-phenylbutyrate and α-, β- and γ-cyclodextrin in solution and evaluation on their taste-masking properties. The Journal of pharmacy and pharmacology 75 (2),236-244頁 (共著)
17.	2023/01	論文	Structural Basis of the Change in the Interaction Between Mycophenolic Acid and Subdomain IIA of Human Serum Albumin During Renal Failure. Journal of medicinal chemistry 66 (1),951-961頁 (共著)
18.	2022/06	論文	Effect of Fatty Acids and Uremic Toxins on the Binding of Nateglinide, an Insulin Secretagogue, to Site II on Human Serum Albumin. Biological & pharmaceutical bulletin 45 (6),803-805頁 (共著)
19.	2022/03	論文	The Nitrated Form of Nateglinide Induces Apoptosis in Human Pancreatic Cancer Cells Through a Caspase-dependent Mechanism. Anticancer research 42 (3),1333-1338頁 (共著)
20.	2022/03	論文	In Vitro and In Vivo Assessment of Atemoya Fruit (Annona atemoya) for Food-Drug Interactions. European journal of drug metabolism and pharmacokinetics 47 (2),177-185頁 (共著)
21.	2022/01	論文	An in-vitro comparative study of the binding of caspofungin and micafungin to plasma proteins. The Journal of pharmacy and pharmacology 74 (1),88-93頁 (共著)
22.	2021/02	論文	Possible Role of Electrolytes on the Formation of Precipitates during the Infusion of Nafamostat Mesilate in Hemodialysis. Biological & pharmaceutical bulletin 44 (2),259-265頁 (共著)
23.	2021/03	論文	Interaction of Benzbromarone with Subdomains IIIA and IB/IIA on Human Serum Albumin as the Primary and Secondary Binding Regions. Molecular pharmaceutics 18 (3),1061-1070頁 (共著)
24.	2021/01	論文	Synthesis and In Vitro Assessment of pH-Sensitive Human Serum Albumin Conjugates of Pirarubicin. Pharmaceuticals (Basel, Switzerland) 14 (1) (共著)
25.	2019/03	論文	Distribution of Caffeic Acid in Ganglioside GD3 (GD3) Monolayer and Mixed Phospholipid/GD3 Monolayer, and Their Interactions J. KUHW 20,75-78頁 (共著)
26.	2018/03	論文	Distribution of Caffeic Acid Ester in Mixed Phospholipid/Ganglioside GD3 Monolayer and their Interaction J. KUHW 19,77-80頁 (共著)
27.	2017/08	論文	Comparison of the pharmacological and biological properties of HPMA copolymer-pirarubicin conjugates: A single-chain copolymer conjugate and its biodegradable tandem-diblock copolymer conjugate European journal of pharmaceutical sciences 106,10-19頁 (共著)
28.	2017/03	論文	Distribution of Caffeic Acid Esters in Ganglioside GM3 Monolayer and There Interactions J. KUHW 18,63-66頁 (共著)
29.	2016/12	論文	Pronounced Cellular Uptake of Pirarubicin versus That of Other Anthracyclines: Comparison of HPMA Copolymer Conjugates of Pirarubicin and Doxorubicin. Molecular pharmaceutics 13 (12),4106-4115頁 (共著)
30.	2016/06	論文	Styrene-maleic acid-copolymer conjugated zinc protoporphyrin as a candidate drug for tumor-targeted therapy and imaging. Journal of drug targeting 24 (5),399-407頁 (共著)
31.	2016/04	論文	A Retrospective 30 Years After Discovery of the Enhanced Permeability and Retention Effect of Solid Tumors: Next-Generation Chemotherapeutics and Photodynamic Therapy--Problems, Solutions, and Prospects. Microcirculation (New York, N.Y. : 1994) 23 (3),173-182頁 (共著)
32.	2016/03	論文	Effect of Caffeic Acid Esters Isolated from Propolis on Ganglioside GD3 Monolayers J. KUHW 17,77-80頁 (共著)
33.	2016/02	論文	pH-sensitive polymeric cisplatin-ion complex with styrene-maleic acid copolymer exhibits tumor-selective drug delivery and antitumor activity as a result of the enhanced permeability and retention effect. Colloids and surfaces. B, Biointerfaces 138,128-137頁 (共著)
34.	2015/03	論文	Synthesis and therapeutic effect of styrene-maleic acid copolymer-conjugated pirarubicin. Cancer science 106 (3),270-278頁 (共著)
35.	2015/01	論文	Effect of different chemical bonds in pegylation of zinc protoporphyrin that affects drug release, intracellular uptake, and therapeutic effect in the tumor. European journal of pharmaceutics and biopharmaceutics 89,259-270頁 (共著)
36.	2013/06	論文	Characterization of carotenoid fatty acid esters from the peels of the persimmon Diospyros kaki. Chemical & pharmaceutical bulletin 61 (6),666-669頁 (共著)
37.	2013/02	論文	Micelles of zinc protoporphyrin conjugated to N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer for imaging and light-induced antitumor effects in vivo. Journal of controlled release : official journal of the Controlled Release Society 165 (3),191-198頁 (共著)
38.	2012/03	論文	Carbon monoxide, generated by heme oxygenase-1, mediates the enhanced permeability and retention effect in solid tumors. Cancer science 103 (3),535-541頁 (共著)
39.	2011/12	論文	Therapeutic potential of pegylated hemin for reactive oxygen species-related diseases via induction of heme oxygenase-1: results from a rat hepatic ischemia/reperfusion injury model. The Journal of pharmacology and experimental therapeutics 339 (3),779-789頁 (共著)
40.	2011/11	論文	Intracellular uptake and behavior of two types zinc protoporphyrin (ZnPP) micelles, SMA-ZnPP and PEG-ZnPP as anticancer agents; unique intracellular disintegration of SMA micelles. Journal of controlled release : official journal of the Controlled Release Society 155 (3),367-375頁 (共著)
41.	2015	著書	水溶性高分子の最新動向 (共著)