Faculty Information - Nakamura Hitomi | SOJO UNIVERSITY

（Last updated : 2024-05-13 13:43:05）

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Nakamura Hitomi

Department / Course FACULTY OF PHARMACEUTICAL SCIENCES Department of Pharmaceutical Sciences

Job

Book and thesis
1.	2024	Papers	Stabilization of adalimumab Fab through the introduction of disulfide bonds between the variable and constant domains. Biochem. Biophys. Res. Commun. 700,pp.149592 (Co-authored)
2.	2023	Papers	Enhancing thermal stability in the CH₂ domain to suppress aggregation through the introduction of simultaneous disulfide bonds in Pichia pastoris. Protein Sci. 32 (12),pp.e4831 (Co-authored)
3.	2023	Papers	Analysis of thermostability for seven Phe to Ala and six Pro to Gly mutants in the Fab constant region of adalimumab. J. Biochem. 174 (4),pp.345-353 (Co-authored)
4.	2022	Papers	Effect of an intermolecular disulfide bond introduced into the first loop of CH1 domain of Adalimumab Fab on thermal stability and antigen-binding activity. J. Biochem. 172 (1),pp.49-56 (Co-authored)
5.	2021	Papers	A comprehensive analysis of novel disulfide bond introduction site into the constant domain of human Fab. Sci. Rep. 11 (1),pp.12937 (Co-authored)
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Academic background
1.	2002/04～2006/03	Faculty of Pharmaceutical Science Kyushu University Graduated
2.	2006/04～2008/03	Master Kyushu University Finished
3.	2012/04～2015/03	Doctorial Kyushu University Finished

Present specialized field
Clinical pharmacy, Pharmaceutical analytical chemistry and physicochemistry