教員情報 - 門脇　大介

カドワキ　ダイスケ Kadowaki Daisuke
門脇　大介

所属薬学部薬学科

職種教授

著書・論文歴
1.	2026/07	論文	Pharmaceutical optimization of chitosan tablets is associated with reduced circulating bile acids and fibrosis-related molecular signatures in non-alcoholic steatohepatitis rats. Carbohydrate polymers 383,125333 (共著)
2.	2026/07	論文	Trends in sodium-glucose transport protein 2 inhibitor prescriptions: application of the ATC/DDD system to NDB open data. Diabetology international 17 (3),40 (共著)
3.	2026/04	論文	Lactulose, a Disaccharide Prebiotic, Improves the Gut-Kidney Axis via Enhancement of Akkermansia Muciniphila Production. Kidney360 7 (4),754-766 (共著)
4.	2026/02/27	論文	カルシミメティクスとCKD-MBD関連薬の処方実態調査 -NDBオープンデータからの分析- 59 (3),1-8頁 (共著)
5.	2025/12/09	論文	日本における経口糖尿病薬の処方動向の変遷 : NDBオープンデータを用いた多年度解析糖尿病 69 (2),28-34頁 (共著)
6.	2025/12	論文	Refinement of Replacement Fluid Using Human Serum Albumin Preparation to Enhance Biocompatibility in Therapeutic Plasma Exchange. Journal of clinical apheresis 40 (6),e70077 (共著)
7.	2025/01/23	論文	心不全シールの導入前後での外来心不全患者の服薬状況と体調管理についての実態調査医療薬学 51 (5),307-317頁 (共著)
8.	2024/03	論文	Therapeutic Effect of Natural Products and Dietary Supplements on Aflatoxin-Induced Nephropathy. International journal of molecular sciences 25 (5) (共著)
9.	2023/06	論文	Evaluation of the Safety and Gastrointestinal Migration of Guanidinylated Chitosan after Oral Administration to Rats. Journal of functional biomaterials 14 (7) (共著)
10.	2022/03	論文	In Vitro and In Vivo Assessment of Atemoya Fruit (Annona atemoya) for Food-Drug Interactions. European journal of drug metabolism and pharmacokinetics 47 (2),177-185 (共著)
11.	2022	論文	The Effects of Sacran, a Sulfated Polysaccharide, on Gut Microbiota Using Chronic Kidney Disease Model Rats. Biological & pharmaceutical bulletin 45 (5),576-582 (共著)
12.	2022	論文	New Insight Concerning Therapeutic Drug Monitoring-The Importance of the Concept of Psychonephrology. Biological & pharmaceutical bulletin 45 (7),834-842 (共著)
13.	2021/07	論文	医薬品マネジメントシステム（DRiFOs）を用いた炭酸ランタンによる胃腸障害の発現状況調査日本病院薬剤師会雑誌 57 (7),776-780頁 (共著)
14.	2020/10	論文	Effect of Cinacalcet on the Redox Status of Albumin in Secondary Hyperparathyroidism Patients Receiving Hemodialysis. Biol Pharm Bull. 43 (10),1583-1590頁 (共著)
15.	2021/12	論文	Evaluation of renal function using cystatin C-based estimated glomerular filtration rate in patients with urothelial carcinoma treated with gemcitabine and cisplatin chemotherapy. Journal of clinical pharmacy and therapeutics 46 (6),1622-1628 (共著)
16.	2020/06	論文	In vivo evaluation of drug dialyzability in a rat model of hemodialysis. PloS one 15 (6),e0233925 (共著)
17.	2021/06	論文	Correction to: Awareness and current implementation of drug dosage adjustment by pharmacists in patients with chronic kidney disease in Japan: a web-based survey. BMC health services research 21 (1),617 (共著)
18.	2020/03	論文	循環器科入院患者における医師と薬剤師の協働による処方適正化の取り組みの成果分析日本老年薬学会雑誌 3 (1),9-14頁 (共著)
19.	2021/03	論文	Sacran, a sulfated polysaccharide, suppresses the absorption of lipids and modulates the intestinal flora in non-alcoholic steatohepatitis model rats. Life sciences 268,118991 (共著)
20.	2020/12	論文	Effects of surface-deacetylated chitin nanofibers on non-alcoholic steatohepatitis model rats and their gut microbiota. Int J Biol Macromol. 164,659-666頁 (共著)
21.	2021	論文	Comparison between the Effects of Loxoprofen and Acetaminophen on Postoperative Pain Following Radical Prostatectomy: A Propensity Score Matching Analysis. Biological & pharmaceutical bulletin 44 (10),1427-1432 (共著)
22.	2020/04	論文	Comparative Study of Constipation Exacerbation by Potassium Binders Using a Loperamide-Induced Constipation Model. International journal of molecular sciences 21 (7) (共著)
23.	2020/08	論文	Investigation of methods for more accurate estimation of kidney function in people with high muscle mass . Clin Nephrol. 96 (2),86-96頁 (共著)
24.	2020/03	論文	Processing grapefruit juice with γ-cyclodextrin attenuates its inhibitory effect on cytochrome P450 3A activity. The Journal of pharmacy and pharmacology 72 (3),356-363 (共著)
25.	2020	論文	Toxicological Property of Acetaminophen: The Dark Side of a Safe Antipyretic/Analgesic Drug? Biological & pharmaceutical bulletin 43 (2),195-206 (共著)
26.	2019/03	論文	Effects of lactulose on renal function and gut microbiota in adenine-induced chronic kidney disease rats. Clinical and experimental nephrology (共著)
27.	2019	論文	Knowledge and awareness of nonpharmacist salespersons regarding over-the-counter drug use in patients with chronic kidney disease in Japan. PloS one 14 (3),e0213763 (共著)
28.	2019/02	論文	Design and Evaluation of An Extended-Release Olmesartan Tablet Using Chitosan/Cyclodextrin Composites. Pharmaceutics 11 (2),E82 (共著)
29.	2019/08	論文	Edoxaban Exerts Antioxidant Effects Through FXa Inhibition and Direct Radical-Scavenging Activity. International journal of molecular sciences 20 (17) (共著)
30.	2019/08	論文	Coefficient of Determination between Estimated and Measured Renal Function in Japanese Patients with Sarcopenia May Be Improved by Adjusting for Muscle Mass and Sex: A Prospective Study. Biological & pharmaceutical bulletin 42 (8),1350-1357 (共著)
31.	2018/06	論文	Benzbromarone Attenuates Oxidative Stress in Angiotensin II- and Salt-Induced Hypertensive Model Rats. Oxid Med Cell Longev. 7635274 (共著)
32.	2018/09	論文	Simple Formula for Predicting Drug Removal Rates During Hemodialysis. Ther Apher Dial. 22 (5),485-493頁 (共著)
33.	2018/02	論文	Ethyl pyruvate attenuates acetaminophen-induced liver injury and prevents cellular injury induced byN-acetyl-p-benzoquinone imine. Heliyon 4 (2),e00521 (共著)
34.	2018/02	論文	Guidelines for treatment of renal injury during cancer chemotherapy 2016. Clinical and experimental nephrology 22 (1),210-244 (共著)
35.	2017/07	論文	A Comparison of the Phosphorus Content in Prescription Medications for Hemodialysis Patients in Japan. Yakugaku Zasshi 137 (7),903-908頁 (共著)
36.	2016/02	論文	Combination therapy with renin-angiotensin-aldosterone system inhibitor telmisartan and serine protease inhibitor camostat mesilate provides further renoprotection in a rat chronic kidney disease model. Journal of pharmacological sciences 130 (2),110-6 (共著)
37.	2016	論文	Effect of a Ferric Citrate Formulation, a Phosphate Binder, on Oxidative Stress in Chronic Kidney Diseases-Mineral and Bone Disorder Patients Receiving Hemodialysis: A Pilot Study. Biological & pharmaceutical bulletin 39 (6),1000-6 (共著)
38.	2016	論文	The Effect of Yokukansan, a Traditional Herbal Preparation Used for the Behavioral and Psychological Symptoms of Dementia, on the Drug-Metabolizing Enzyme Activities in Healthy Male Volunteers. Biological & pharmaceutical bulletin 39 (9),1468-74 (共著)
39.	2015/12	論文	Olmesartan protects endothelial cells against oxidative stress-mediated cellular injury. Clinical and experimental nephrology 19 (6),1007-14 (共著)
40.	2015/02	論文	p-Cresyl sulfate, a uremic toxin, causes vascular endothelial and smooth muscle cell damages by inducing oxidative stress. Pharmacology research & perspectives 3 (1),e00092 (共著)
41.	2015	論文	Direct radical scavenging activity of benzbromarone provides beneficial antioxidant properties for hyperuricemia treatment. Biological & pharmaceutical bulletin 38 (3),487-92 (共著)
42.	2015	論文	The serine protease inhibitor camostat mesilate attenuates the progression of chronic kidney disease through its antioxidant effects. Nephron 129 (3),223-32 (共著)
43.	2014/12	論文	Awareness and current implementation of drug dosage adjustment by pharmacists in patients with chronic kidney disease in Japan: a web-based survey. BMC health services research 14,615 (共著)
44.	2014/10	論文	Possible false-negative results on therapeutic drug monitoring of phenytoin using a particle enhanced turbidimetric inhibition immunoassay in a patient with a high level of IgM. Therapeutic drug monitoring 36 (5),553-5 (共著)
45.	2014	論文	Cys34-cysteinylated human serum albumin is a sensitive plasma marker in oxidative stress-related chronic diseases. PloS one 9 (1),e85216 (共著)
46.	2014	論文	Differential effects of methoxy group on the interaction of curcuminoids with two major ligand binding sites of human serum albumin. PloS one 9 (2),e87919 (共著)
47.	2013/06	論文	Comparative effects of respiratory stimulants on hypoxic neuronal cell injury in SH-SY5Y cells and in hippocampal slice cultures from rat pups. Pediatrics international : official journal of the Japan Pediatric Society 55 (3),320-7 (共著)
48.	2013/04	論文	p-Cresyl sulfate causes renal tubular cell damage by inducing oxidative stress by activation of NADPH oxidase. Kidney international 83 (4),582-92 (共著)
49.	2013/03	論文	Phosphoenolpyruvate, a glycolytic intermediate, as a cytoprotectant and antioxidant in ex-vivo cold-preserved mouse liver: a potential application for organ preservation. The Journal of pharmacy and pharmacology 65 (3),390-401 (共著)
50.	2013	論文	Comparative Effects of Phosphoenolpyruvate, a Glycolytic Intermediate, as an Organ Preservation Agent with Glucose and N-Acetylcysteine against Organ Damage during Cold Storage of Mouse Liver and Kidney. ISRN pharmacology 2013,375825 (共著)
51.	2012/12	論文	Effect of acetaminophen on the progression of renal damage in adenine induced renal failure model rats. Life sciences 91 (25-26),1304-8 (共著)
52.	2012/11	論文	A uremic toxin, 3-carboxy-4-methyl-5-propyl-2-furanpropionate induces cell damage to proximal tubular cells via the generation of a radical intermediate. Biochemical pharmacology 84 (9),1207-14 (共著)
53.	2012/07	論文	Interaction between two sulfate-conjugated uremic toxins, p-cresyl sulfate and indoxyl sulfate, during binding with human serum albumin. Drug metabolism and disposition: the biological fate of chemicals 40 (7),1423-8 (共著)
54.	2012	論文	[Drug induced nephropathy and appropriate use of drugs]. Nihon Jinzo Gakkai shi 54 (7),999-1005 (共著)
55.	2012	論文	Appropriate drug dosing in patients receiving peritoneal dialysis. Contributions to nephrology 177,30-7 (共著)
56.	2012	論文	Phosphoenolpyruvic acid, an intermediary metabolite of glycolysis, as a potential cytoprotectant and anti-oxidant in HeLa cells. Biological & pharmaceutical bulletin 35 (4),606-11 (共著)
57.	2011/09	論文	Quantitative analysis of cysteine-34 on the anitioxidative properties of human serum albumin in hemodialysis patients. Journal of pharmaceutical sciences 100 (9),3968-76 (共著)
58.	2011/08	論文	Loss of functional albumin triggers acceleration of transthyretin amyloid fibril formation in familial amyloidotic polyneuropathy. Laboratory investigation; a journal of technical methods and pathology 91 (8),1219-28 (共著)
59.	2011/08	論文	Organic anion transporters play an important role in the uptake of p-cresyl sulfate, a uremic toxin, in the kidney. Nephrology, dialysis, transplantation 26 (8),2498-502 (共著)
60.	2011/06	論文	Removal of doripenem during hemodialysis and the optimum dosing regimen for patients undergoing hemodialysis. Therapeutic apheresis and dialysis 15 (3),327-33 (共著)
61.	2011/04	論文	Fluid resuscitation with hemoglobin vesicles prevents Escherichia coli growth via complement activation in a hemorrhagic shock rat model. The Journal of pharmacology and experimental therapeutics 337 (1),201-8 (共著)
62.	2011/04	論文	Spectroscopic studies of interactions of chondroitin sulfates with cisplatin. Carbohydrate research 346 (5),631-7 (共著)
63.	2011/04	論文	Vitamin D receptor activator reduces oxidative stress in hemodialysis patients with secondary hyperparathyroidism. Therapeutic apheresis and dialysis 15 (2),161-8 (共著)
64.	2011/03	論文	Repeated injection of high doses of hemoglobin-encapsulated liposomes (hemoglobin vesicles) induces accelerated blood clearance in a hemorrhagic shock rat model. Drug metabolism and disposition: the biological fate of chemicals 39 (3),484-9 (共著)
65.	2011	論文	Toxicodynamic evaluation of a cisplatin-chondroitin sulfate complex using a perfused kidney and human proximal tubular cells. Renal failure 33 (6),609-14 (共著)
66.	2010/11	論文	Hepatically-metabolized and -excreted artificial oxygen carrier, hemoglobin vesicles, can be safely used under conditions of hepatic impairment. Toxicology and applied pharmacology 248 (3),234-41 (共著)
67.	2010/07	論文	The uremic solute indoxyl sulfate acts as an antioxidant against superoxide anion radicals under normal-physiological conditions. FEBS letters 584 (13),2816-20 (共著)
68.	2010	論文	Construction of an expression system for human alpha(1)-acid glycoprotein in E. coli: The roles of oligosaccharide moieties in structural and functional properties. Drug metabolism and pharmacokinetics 25 (2),200-7 (共著)
69.	2010	論文	Receptor-mediated uptake of human alpha1-acid glycoprotein into liver parenchymal cells in mice. Drug metabolism and pharmacokinetics 25 (1),101-7 (共著)
70.	2009/12	論文	Evaluation for antioxidant and renoprotective activity of olmesartan using nephrectomy rats. Biological & pharmaceutical bulletin 32 (12),2041-5 (共著)
71.	2009/11	論文	A site-directed mutagenesis study of drug-binding selectivity in genetic variants of human alpha(1)-acid glycoprotein. Journal of pharmaceutical sciences 98 (11),4316-26 (共著)
72.	2009/11	論文	Hemoglobin vesicles, polyethylene glycol (PEG)ylated liposomes developed as a red blood cell substitute, do not induce the accelerated blood clearance phenomenon in mice. Drug metabolism and disposition: the biological fate of chemicals 37 (11),2197-203 (共著)
73.	2009/02	論文	[To facilitate the compliance of phosphate binder for the control of hyperphosphatemia in chronic kidney disease patients]. Clinical calcium 19 (2),248-52 (共著)
74.	2009/01	論文	Antioxidant effects of a dietary supplement: reduction of indices of oxidative stress in normal subjects by water-soluble chitosan. Food and chemical toxicology 47 (1),104-9 (共著)
75.	2007/07	論文	Alpha1-acid glycoprotein suppresses rat acute inflammatory paw edema through the inhibition of neutrophils activation and prostaglandin E2 generation. Biological & pharmaceutical bulletin 30 (7),1226-30 (共著)
76.	2007/05	論文	Effect of olmesartan on oxidative stress in hemodialysis patients. Hypertension research : official journal of the Japanese Society of Hypertension 30 (5),395-402 (共著)