Faculty Information - Yamasaki Keishi

Yamasaki Keishi

Department / Course FACULTY OF PHARMACEUTICAL SCIENCES Department of Pharmaceutical Sciences

Job

Book and thesis
1.	2026	Papers	Interaction of Febuxostat with Human Serum Albumin and Its Application as a Circular Dichroism Probe for Monitoring Albumin Conformational Changes ACS Omega (Co-authored)
2.	2026	Papers	Antitumor efficacy and reduced systemic toxicity of palmitic acid-modified pirarubicin nanoparticles in mice. Cancer Chemother Pharmacol 96 (52) (Co-authored)
3.	2026	Papers	Mechanistic Insights into pH-Responsive Drug Release and Antitumor Effects of an Albumin-Pirarubicin Conjugate. Pharm Res (Co-authored)
4.	2026	Papers	A Phenylbutyrate-Derived Nitric Oxide Donor Induces Pancreatic Cancer Cell Death Accompanied by Impairment of Autophagy-Related Pathways and HIF-1α Reduction. Biol Pharm Bull 49 (7),pp.1161-1168 (Co-authored)
5.	2026	Papers	Elucidation of Cefmetazole Binding to Human Serum Albumin In Vitro and Prediction of Unbound Cefmetazole Concentrations in Clinical Patients. Keio J Med,pp.doi: 10.2302/kjm.2026-0001-OA. (Co-authored)
6.	2026	Papers	Caspase-Independent Cell Death Induced by a Nitric Oxide Donor Derived from Valproic Acid in Human Pancreatic Cancer Cells. Biol Pharm Bull 49,pp.452-456 (Co-authored)
7.	2026	Papers	Preparation and evaluation of hydrophobin-pirarubicin glucosamine-containing nanoparticles as an anticancer formulation. Int J Biol Macromol.,pp.150460 (Co-authored)
8.	2025	Papers	Secreted protein acidic and rich in cysteine-guided biomimetic delivery of nano-antioxidants reverses muscle atrophy in a mouse model of sarcopenia. (Co-authored)
9.	2025	Papers	Insights into Dual Binding Modes of Nateglinide to Human Serum Albumin. ACS Med Chem Lett doi: 10.1021/acsmedchemlett.5c00277 (Co-authored)
10.	2025	Papers	Lymph node macrophage-targeted interferon alpha boosts anticancer immune responses by regulating CD169-positive phenotype of macrophages. Molecular cancer 24 (1),pp.132 (Co-authored)
11.	2024	Papers	Interaction of Cephalosporins with Human Serum Albumin: A Structural Study. J Med Chem 67,pp.14175-14183 (Co-authored)
12.	2024	Papers	The preparation and evaluation of granulated chitosan-catechin tablets with excellent disintegration properties. Carbohydr Res. 547,pp.109308 (Co-authored)
13.	2024	Papers	Qualitative and quantitative status of cytochrome P450s after the administration of a liposomal platelet substitute in rat liver. (Co-authored)
14.	2024	Papers	Ibuprofen‑derived nitric oxide donors with a high affinity to human serum albumin induce cell death in pancreatic cancer cells through a non‑caspase 3/7‑mediated pathway. Biomed Rep 21,pp.159 (Co-authored)
15.	2024	Papers	Novel Diclofenac-NO Donor With High Affinity for Human Serum Albumin Induces Endoplasmic Reticulum Stress-mediated Cell Death in Human Pancreatic Cancer Cells. Anticancer Res 44,pp.3793-3798 (Co-authored)
16.	2024	Papers	7-Phenylheptanoic acid-Hydroxypropyl β-Cyclodextrin Complex Slows the Progression of Renal Failure in Adenine-Induced Chronic Kidney Disease Mice. Toxins 16,pp.316 (Co-authored)
17.	2024	Papers	Possible Involvement of Protein Binding Inhibition in Changes in Dexmedetomidine Concentration in Extracorporeal Circuits during Midazolam Use. Biological & pharmaceutical bulletin 47 (2),pp.389-393 (Co-authored)
18.	2024	Papers	Development of α-Cyclodextrin-Based Orally Disintegrating Tablets for 4-Phenylbutyrate. Pharmaceutics 16,pp.82 (Co-authored)
19.	2024	Papers	Preparation and in vitro characterization of fatty-acid modified pirarubicin nanosuspensions stabilized by albumin. Chem Pharm Bull 72,pp.21-27 (Co-authored)
20.	2023	Papers	Study of the Structural Chemistry of the Inclusion Complexation of 4-Phenylbutyrate and Related Compounds with Cyclodextrins in Solution: Differences in Inclusion Mode with Cavity Size Dependency. Int J Mol Sci 24,pp.15091 (Co-authored)
21.	2023	Papers	Encapsulation of an Antioxidant in Redox-Sensitive Self-Assembled Albumin Nanoparticles for the Treatment of Hepatitis. ACS Nano doi: 10.1021/acsnano.3c02877 (Co-authored)
22.	2023	Papers	Structural basis of the change in the interaction between mycophenolic acid and subdomain IIA of human serum albumin during renal failure. J Med Chem 66,pp.951-961 (Co-authored)
23.	2023	Papers	Study of the Inclusion Complexes Formed Between 4-Phenylbutyrate and α-, β-, and γ-Cyclodextrin in Solution and Evaluation on Their Taste-Masking Properties. J Pharm Pharmacol 75,pp.236-244 (Co-authored)
24.	2022	Papers	The Chlorine Atoms of Aripiprazole Molecule Control the Geometry and Motion of Aripiprazole and Deschloro-aripiprazole in the Subdomain IIIA of Human Serum Albumin. ACS Omega doi.org/10.1021/acsomega.2c02929 (Co-authored)
25.	2022	Papers	An in vitro comparative study of the binding of caspofungin and micafungin to plasma proteins. J Pharm Pharmacol 74,pp.88-93 (Co-authored)
26.	2022	Papers	Novel nitric oxide donor, nitrated phenylbutyrate, induces cell death of human pancreatic cancer cells and suppress tumor growth of cancer xenografts. Oncology Reports 48,pp.178 (Co-authored)
27.	2022/03	Papers	The Nitrated Form of Nateglinide Induces Apoptosis in Human Pancreatic Cancer Cells Through a Caspase-dependent Mechanism. Anticancer research 42 (3),pp.1333-1338 (Co-authored)
28.	2022	Papers	Effect of Fatty Acids and Uremic Toxins on the binding of Nateglinide, an Insulin Secretagogue, to Site II on Human Serum Albumin Biol. Pharm. Bull. 45,pp.803-805 (Co-authored)
29.	2022	Papers	Effects of Myristate on the Induced Circular Dichroism Spectra of Aripiprazole Bound to Human Serum Albumin: A Structural–Chemical Investigation ACS OMEGA 7 (5),pp.4413-4419 (Co-authored)
30.	2022	Papers	In vitro and in vivo assessment of Atemoya fruit (Annona atemoya) for food-drug interaction. Eur J Drug Metab Pharmacokinet 47,pp.177-185 (Co-authored)
31.	2022	Papers	Trimethoxy trityl groups as a potent substituent for anti-cancer cytidine analog prodrugs. J Pharm Sci doi: 10.1016/j.xphs.2022.04.020 (Co-authored)
32.	2021	Papers	The Binding of Aripiprazole to Plasma Proteins in Chronic Renal Failure Patients toxins 13,pp.811 (Co-authored)
33.	2021	Papers	Possible role of electrolytes on the formation of precipitates during the infusion of nafamostat mesilate in hemodialysis Biol Pharm Bull 44 (2),pp.259-265 (Co-authored)
34.	2021	Papers	Interaction of benzbromarone with subdomains IIIA and IB/IIA on human serum albumin as the primary and secondary binding regions. Mol Pharm doi: 10.1021/acs.molpharmaceut.0c01004 (Co-authored)
35.	2021	Papers	Effects of Uremic Toxins on the Binding of Aripiprazole to Human Serum Albumin. Biol Pharm Bull 44 (3),pp.437-441 (Co-authored)
36.	2021	Papers	Possible roles of intestinal P-glycoprotein and cytochrome P450 3A on the limited oral absorption of irinotecan. J Pharm Pharmacol. (Co-authored)
37.	2021	Papers	Pharmacokinetics of 4'-cyano-2'-deoxyguanosine, a novel nucleoside analog inhibitor of the resistant hepatitis B virus, in a rat model of chronic kidney disease. J Infect Chemother 27,pp.702-706 (Co-authored)
38.	2021	Papers	Antipruritic and anti-herpes virus activities of bisabolol oxide A, the main constituent in the essential oil of German chamomile (Matricaria recutita L.) Cur Top Phytochem 17,pp.63-68 (Co-authored)
39.	2020	Papers	Processing grapefruit juice with γ-cyclodextrin attenuates its inhibitory effect on cytochrome P450 3A activity. J Pharm Pharmacol doi: 10.1111/jphp.13212 (Co-authored)
40.	2020	Papers	Characterization of the interaction of daptomycin with site II on human serum albumin. Journal of pharmaceutical sciences https://doi.org/10.1016/j.xphs.2020.06.011 (Co-authored)
41.	2020	Papers	Effects of Oxidation of Human Serum Albumin on the Binding of Aripiprazole. Biol Pharm Bull 43,pp.1023-1026 (Co-authored)
42.	2020	Papers	Characterization of Bovine Lactoferrin Nanoparticle Prepared by Desolvation Technique Chem Pharm Bull (Tokyo) . 68 (8),pp.766-772 (Co-authored)
43.	2020	Papers	Hepatic cytochrome P450 profiles in hemorrhagic shock model rats after transfusion with stored red blood cells. J Pharm Sci doi: 10.1016/j.xphs.2020.08.015. (Co-authored)
44.	2020	Papers	Evaluation of cytochrome P450-based drug metabolism in hemorrhagic shock rats that were transfused with native and an artificial red blood cell preparation, Hemoglobin-vesicles. 35,pp.417-424 (Co-authored)
45.	2020	Papers	Assessing cytochrome P450-based drug-drug interactions with Hemoglobin-vesicles, an artificial red blood cell preparation, in healthy rats. doi.org/10.1016/j.dmpk.2020.06.005 (Co-authored)
46.	2020	Papers	A Safety Evaluation Study in Mice Revealed that Albumin Dimer is Safe for Medical and Pharmaceutical Applications BPB Reports 3 (2),pp.87-91 (Co-authored)
47.	2020	Papers	Serum Albumin, Lipid and Drug Binding,pp.383-397 (Co-authored)
48.	2020	Papers	In Vivo Evaluation of Drug Dialyzability in a Rat Model of Hemodialysis PLoS One 15 (6),pp.e0233925 (Co-authored)
49.	2019	Papers	Investigation of anti-tumor effect of doxorubicin-loaded human serum albumin nanoparticles prepared by a desolvation technique. Cancer Chemother Pharmacol. 83,pp.1113-1120 (Co-authored)
50.	2019	Papers	Enhanced dissolution and oral bioavailability of praziquantel by emulsification with human serum albumin followed by spray drying. European journal of pharmaceutical science 139,pp.105064 (Co-authored)
51.	2019	Papers	Further Evidence Regarding the Important Role of Chlorine Atoms of Aripiprazole on Binding to the Site II Area of Human Albumin. J Pharm Sci. 108,pp.1890-1895 (Co-authored)
52.	2019	Papers	Cell uptake and anti-tumor effect of liposomes containing encapsulated paclitaxel-bound albumin against breast cancer cells in 2D and 3D cultured models. Journal of Drug Delivery Science and Technology (Co-authored)
53.	2019/07	Papers	α₁-Acid Glycoprotein Has the Potential to Serve as a Biomimetic Drug Delivery Carrier for Anti-Cancer Agents. Journal of pharmaceutical sciences (Co-authored)
54.	2019	Papers	Preparation, Characterization, and in Vitro/in Vivo Evaluation of Paclitaxel-Bound Albumin-Encapsulated Liposomes for the Treatment of Pancreatic Cancer ACS Omega 4,pp.8693-8700 (Co-authored)
55.	2019/09	Papers	Interaction of Aripiprazole with Human α1-Acid Glycoprotein. Journal of pharmaceutical sciences (Co-authored)
56.	2018	Papers	Preparation and in Vitro Analysis of Human Serum Albumin Nanoparticles Loaded with Anthracycline Derivatives. Chemical & pharmaceutical bulletin 66 (4),pp.382-390 (Co-authored)
57.	2018	Papers	Analysis of the Binding of Aripiprazole to Human Serum Albumin: The Importance of a Chloro-Group in the Chemical Structure. ACS omega 3 (10),pp.13790-13797 (Co-authored)
58.	2018/11	Papers	Biomimetic carbon monoxide delivery based on hemoglobin vesicles ameliorates acute pancreatitis in mice via the regulation of macrophage and neutrophil activity. Drug delivery 25 (1),pp.1266-1274 (Co-authored)
59.	2018/07	Papers	Metal-catalyzed oxidation of human serum albumin does not alter the interactive binding to the two principal drug binding sites. Biochemistry and biophysics reports 14,pp.155-160 (Co-authored)
60.	2018/06	Papers	Pharmacokinetics studies of 4'-cyano-2'-deoxyguanosine, a potent inhibitor of the hepatitis B virus, in rats. The Journal of pharmacy and pharmacology 70 (6),pp.723-731 (Co-authored)
61.	2018/03	Papers	Effect of endogenous substances on the binding of sodium 4-phenylbutyrate to human serum albumin. Acta Chim Pharm Indica 8,pp.124-129 (Co-authored)
62.	2018/03	Papers	Effect of endogenous substances on the binding of sodium 4-phenylbutyrate to human serum albumin. Acta Chim Pharm Indica 8,pp.124-129 (Co-authored)
63.	2018/03	Papers	Crystal structure analysis of human serum albumin complexed with sodium 4-phenylbutyrate. Biochemistry and biophysics reports 13,pp.78-82 (Co-authored)
64.	2018/01	Papers	Albumin-Encapsulated Liposomes: A Novel Drug Delivery Carrier With Hydrophobic Drugs Encapsulated in the Inner Aqueous Core. Journal of pharmaceutical sciences 107 (1),pp.436-445 (Co-authored)
65.	2018	Papers	Pharmacokinetic properties of a novel inosine analog, 4'-cyano-2'-deoxyinosine, after oral administration in rats. PloS one 13 (6),pp.e0198636 (Co-authored)
66.	2018	Papers	In vivo drug delivery eﬃciency of albumin-encapsulated liposomes as hydrophobic drug carriers Journal of Drug Delivery Science and Technology 47,pp.62-66 (Co-authored)
67.	2018	Papers	Glutamine deprivation enhances acetyl-CoA carboxylase inhibitor-induced death of human pancreatic cancer cells. Anticancer Res 38,pp.6683-6689 (Co-authored)
68.	2017/12	Papers	Interaction of Protizinic Acid with Human Serum Albumin: Site-to-Site Displacement of Protizinic Acid by Ibuprofen Acta Chim Pharm Indica 7 (3),pp.115-123 (Co-authored)
69.	2017/09	Papers	The Use of Hemoglobin Vesicles for Delivering Medicinal Gas for the Treatment of Intractable Disorders. Journal of pharmaceutical sciences 106 (9),pp.2392-2400 (Co-authored)
70.	2017/09	Papers	Species Differences in the Binding of Sodium 4-Phenylbutyrate to Serum Albumin. Journal of pharmaceutical sciences 106 (9),pp.2860-2867 (Co-authored)
71.	2017/08	Papers	Crystallographic analysis of the ternary complex of octanoate and N-acetyl-l-methionine with human serum albumin reveals the mode of their stabilizing interactions. Biochimica et biophysica acta. Proteins and proteomics 1865 (8),pp.979-984 (Co-authored)
72.	2017/03	Papers	Comparison of the Pharmacokinetic Properties of Hemoglobin-Based Oxygen Carriers. Journal of functional biomaterials 8 (1) (Co-authored)
73.	2017	Papers	The Binding of Silibinin, the Main Constituent of Silymarin, to Site I on Human Serum Albumin. Biological & pharmaceutical bulletin 40 (3),pp.310-317 (Co-authored)
74.	2017	Papers	Recombinant Human Serum Albumin Containing 3 Copies of Domain I, Has Significant in Vitro Antioxidative Capacity Compared to the Wild-Type. Biological & pharmaceutical bulletin 40 (10),pp.1813-1817 (Co-authored)
75.	2017	Papers	Long chain fatty acids alter the interactive binding of ligands to the two principal drug binding sites of human serum albumin. PloS one 12 (6),pp.e0180404 (Co-authored)
76.	2017	Papers	Albumin-encapsulated liposomes: A novel drug delivery carrier with hydrophobic drugs encapsulated in the inner aqueous core. J Pharm Sci S0022-3549(17)30567-1. doi: 10 (Co-authored)
77.	2016/10	Papers	Long-Term Stored Hemoglobin-Vesicles, a Cellular Type of Hemoglobin-Based Oxygen Carrier, Has Resuscitative Effects Comparable to That for Fresh Red Blood Cells in a Rat Model with Massive Hemorrhage without Post-Transfusion Lung Injury. PloS one 11 (10),pp.e0165557 (Co-authored)
78.	2016/07	Papers	N-acetyl-L-methionine is a superior protectant of human serum albumin against post-translational oxidation as compared to N-acetyl-L-tryptophan. Biochemistry and biophysics reports 6,pp.266-274 (Co-authored)
79.	2016/07	Papers	Evaluation of a new type of nano-sized carbon monoxide donor on treating mice with experimentally induced colitis. Journal of controlled release : official journal of the Controlled Release Society 234,pp.49-58 (Co-authored)
80.	2016/06	Papers	Tyrosine411 and Arginine410 of Human Serum Albumin Play an Important Role in the Binding of Sodium 4-Phenylbutyrate to Site II. Journal of pharmaceutical sciences 105 (6),pp.1987-1994 (Co-authored)
81.	2016/03	Papers	Comparison of Posttranslational Modification and the Functional Impairment of Human Serum Albumin in Commercial Preparations. Journal of pharmaceutical sciences 105 (3),pp.1043-9 (Co-authored)
82.	2016	Papers	Long-Term Stored Hemoglobin-Vesicles, a Cellular Type of Hemoglobin-Based Oxygen Carrier, Has Resuscitative Effects Comparable to That for Fresh Red Blood Cells in a Rat Model with Massive Hemorrhage without Post-Transfusion Lung Injury. PloS one 11 (10),pp.e0165557 (Co-authored)
83.	2016	Papers	Effect of a Ferric Citrate Formulation, a Phosphate Binder, on Oxidative Stress in Chronic Kidney Diseases-Mineral and Bone Disorder Patients Receiving Hemodialysis: A Pilot Study. Biological & pharmaceutical bulletin 39 (6),pp.1000-6 (Co-authored)
84.	2015/10	Papers	Establishment of a model of acetaminophen-induced hepatotoxicity in different weekly-aged ICR mice. Laboratory animals 49 (4),pp.294-301 (Co-authored)
85.	2015/08	Papers	Potential Use of Biological Proteins for Liver Failure Therapy. Pharmaceutics 7 (3),pp.255-74 (Co-authored)
86.	2015/02	Papers	Cross-linked human serum albumin dimer has the potential for use as a plasma-retaining agent for the fatty acid-conjugated antidiabetic drugs. The Journal of pharmacy and pharmacology 67 (2),pp.255-63 (Co-authored)
87.	2015	Papers	Interactions of Linezolid with Two Major Serum Proteins, Human Serum Albumin and Alpha-1 Acid Glycoprotein. J Pharmacol Clin Toxicol 3,pp.1045 (Co-authored)
88.	2015	Papers	Biological Responsiveness and Metabolic Performance of Liposome-Encapsulated Hemoglobin (Hemoglobin-Vesicles) in Apolipoprotein E-Deficient Mice after Massive Intravenous Injection. Biological & pharmaceutical bulletin 38 (10),pp.1606-16 (Co-authored)
89.	2014/09	Papers	N-acetyl-l-methionine is a superior protectant of human serum albumin against photo-oxidation and reactive oxygen species compared to N-acetyl-L-tryptophan. Biochimica et biophysica acta 1840 (9),pp.2806-12 (Co-authored)
90.	2014	Papers	Differential effects of methoxy group on the interaction of curcuminoids with two major ligand binding sites of human serum albumin. PloS one 9 (2),pp.e87919 (Co-authored)
91.	2014	Papers	An evaluation of novel biological activity in a crude extract from Hemerocallis fulva L. var. sempervirens M. Hotta. Natural product research 28 (23),pp.2211-3 (Co-authored)
92.	2013/12	Papers	Effect of albumin on transthyretin and amyloidogenic transthyretin Val30Met disposition and tissue deposition in familial amyloidotic polyneuropathy. Life sciences 93 (25-26),pp.1017-22 (Co-authored)
93.	2013/12	Papers	Albumin-drug interaction and its clinical implication. Biochimica et biophysica acta 1830 (12),pp.5435-43 (Co-authored)
94.	2013/04	Papers	Pharmacokinetic alteration of (99m)Tc-MAG3 using serum protein binding displacement method. Nuclear medicine and biology 40 (3),pp.366-70 (Co-authored)
95.	2011/11	Papers	Enhanced dissolution of inhalable cyclosporine nano-matrix particles with mannitol as matrix former. International journal of pharmaceutics 420 (1),pp.34-42 (Co-authored)
96.	2011/04	Papers	Histidine146 of human serum albumin plays a prominent role at the interface of subdomains IA and IIA in allosteric ligand binding. IUBMB life 63 (4),pp.277-85 (Co-authored)
97.	2010/10	Papers	Enhancement of the aqueous solubility and masking the bitter taste of famotidine using drug/SBE-beta-CyD/povidone K30 complexation approach. Journal of pharmaceutical sciences 99 (10),pp.4285-94 (Co-authored)
98.	2010/09	Papers	Evaluation of carboxymethyl-beta-cyclodextrin with acid function: improvement of chemical stability, oral bioavailability and bitter taste of famotidine. International journal of pharmaceutics 397 (1-2),pp.1-8 (Co-authored)
99.	2010/07	Papers	Enhancement of dissolution and bioavailability of flurbiprofen by low molecular weight chitosans. Die Pharmazie 65 (7),pp.461-6 (Co-authored)
100.	2009/08	Papers	Competitive displacement of serum protein binding of radiopharmaceuticals with amino acid infusion investigated with N-isopropyl-p-123I-iodoamphetamine. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 50 (8),pp.1378-83 (Co-authored)
101.	2008/02	Papers	Inhibitory effects of fruit juices on cytochrome P450 2C9 activity in vitro. Bioscience, biotechnology, and biochemistry 72 (2),pp.406-11 (Co-authored)
102.	2008/01	Papers	Subdomain IIIA of dog albumin contains a binding site similar to site II of human albumin. Drug metabolism and disposition: the biological fate of chemicals 36 (1),pp.81-6 (Co-authored)
103.	2007/02	Papers	The role of N-acetyl-methioninate as a new stabilizer for albumin products. Int J Pharm 329 (1-2),pp.19-24 (Co-authored)
104.	2007/02	Papers	Effects of pomegranate juice on human cytochrome P450 2C9 and tolbutamide pharmacokinetics in rats. Drug metabolism and disposition: the biological fate of chemicals 35 (2),pp.302-5 (Co-authored)
105.	2007/02	Papers	Adsorption of irinotecan onto oral adsorbent AST-120 (Kremezin) for preventing delayed diarrhea. Cancer chemotherapy and pharmacology 59 (3),pp.321-8 (Co-authored)
106.	2007	Papers	The role of N-acetyl-methioninate as a new stabilizer for albumin products. Int J Pharm 329,pp.19-24 (Co-authored)
107.	2006/04	Papers	Oxidation of Arg-410 promotes the elimination of human serum albumin. Biochimica et biophysica acta 1764 (4),pp.743-9 (Co-authored)
108.	2006/03	Papers	Transient inhibition of cyp3a in rats by star fruit juice. Drug metabolism and disposition: the biological fate of chemicals 34 (3),pp.343-5 (Co-authored)
109.	2005/12	Papers	Hydrolysis of angiotensin II receptor blocker prodrug olmesartan medoxomil by human serum albumin and identification of its catalytic active sites. Drug metabolism and disposition: the biological fate of chemicals 33 (12),pp.1911-9 (Co-authored)
110.	2005/05	Papers	Effects of pomegranate juice on human cytochrome p450 3A (CYP3A) and carbamazepine pharmacokinetics in rats. Drug metabolism and disposition: the biological fate of chemicals 33 (5),pp.644-8 (Co-authored)
111.	2005/04	Papers	Bucolome, a potent binding inhibitor for furosemide, alters the pharmacokinetics and diuretic effect of furosemide: potential for use of bucolome to restore diuretic response in nephrotic syndrome. Drug metabolism and disposition: the biological fate of chemicals 33 (4),pp.596-602 (Co-authored)
112.	2005/03	Papers	Inhibitory effects of amino-acid fluids on drug binding to site II of human serum albumin in vitro. Biological & pharmaceutical bulletin 28 (3),pp.549-52 (Co-authored)
113.	2004/12	Papers	Characterization of site I of human serum albumin using spectroscopic analyses: locational relations between regions Ib and Ic of site I. Journal of pharmaceutical sciences 93 (12),pp.3004-12 (Co-authored)
114.	2004/06	Papers	Potent inhibition by star fruit of human cytochrome P450 3A (CYP3A) activity. Drug metabolism and disposition: the biological fate of chemicals 32 (6),pp.581-3 (Co-authored)
115.	2003/09	Papers	Inhibitory effects of citrus fruits on cytochrome P450 3A (CYP3A) activity in humans. Biological & pharmaceutical bulletin 26 (9),pp.1371-3 (Co-authored)
116.	2003	Papers	Effect of P-glycoprotein modulator, cyclosporin A, on the gastrointestinal excretion of irinotecan and its metabolite SN-38 in rats. Pharm Res. 20,pp.910-917 (Co-authored)
117.	2001/12	Papers	In vitro and in vivo properties of recombinant human serum albumin from Pichia pastoris purified by a method of short processing time. Pharmaceutical research 18 (12),pp.1775-81 (Co-authored)
118.	2001/05	Papers	Effect of oxidative stress on the structure and function of human serum albumin. Pharmaceutical research 18 (5),pp.632-9 (Co-authored)
119.	2001/04	Papers	Interaction mechanism between indoxyl sulfate, a typical uremic toxin bound to site II, and ligands bound to site I of human serum albumin. Pharmaceutical research 18 (4),pp.520-4 (Co-authored)
120.	2000/05	Papers	Circular dichroism simulation shows a site-II-to-site-I displacement of human serum albumin-bound diclofenac by ibuprofen. AAPS PharmSciTech 1 (2),pp.E12 (Co-authored)
121.	1999/07	Papers	Interactive binding to the two principal ligand binding sites of human serum albumin: effect of the neutral-to-base transition. Biochimica et biophysica acta 1432 (2),pp.313-23 (Co-authored)
122.	1996/07	Papers	Mode of interaction of loop diuretics with human serum albumin and characterization of binding site. Pharmaceutical research 13 (7),pp.1015-9 (Co-authored)
123.	1996/07	Papers	Characterization of site I on human serum albumin: concept about the structure of a drug binding site. Biochimica et biophysica acta 1295 (2),pp.147-57 (Co-authored)
124.	1994/12	Papers	Characterization of region Ic in site I on human serum albumin. Microenvironmental analysis using fluorescence spectroscopy. Biological & pharmaceutical bulletin 17 (12),pp.1656-62 (Co-authored)
125.	1994/10	Papers	Interaction of benzothiadiazides with human serum albumin studied by dialysis and spectroscopic methods. Pharmaceutical research 11 (10),pp.1452-7 (Co-authored)
126.	1993/11	Papers	Study of interaction of carprofen and its enantiomers with human serum albumin--I. Mechanism of binding studied by dialysis and spectroscopic methods. Biochemical pharmacology 46 (10),pp.1721-31 (Co-authored)
127.	1993/11	Papers	Characterization of high affinity binding sites of non-steroidal anti-inflammatory drugs with respect to site-specific probes on human serum albumin. Biological & pharmaceutical bulletin 16 (11),pp.1169-74 (Co-authored)