■ Book and thesis
1.
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1996
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Article
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Identification of binding sites for calcium channel antagonists. Jpn. Heart J. 37,,pp.643-650 (Collaboration)
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2.
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1998
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Article
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Photochemical identification of transmembrane segment IVS6 as the binding region of semotiadil, a new modulator for the L-type voltage-dependent Ca2+ channel. J. Biol. Chem. 273,pp.4635-4641 (Collaboration)
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3.
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1999
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Article
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[35S] S-[5-(4-benzoylphenyl) pentyl] glutathione: a versatile radioligand targeting GS-X pumps with the ability of photoaffinity labeling. Bioorg. Med. Chem. Lett. 9,pp.2661-2666 (Collaboration)
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4.
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1999
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Article
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A new scorpion toxin (BmK-PL) stimulates Ca2+-release channel activity of the skeletal-muscle ryanodine receptor by an indirect mechanism. Biochem. J. 339,pp.343-350 (Collaboration)
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5.
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2000
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Article
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Glibenclamide acts as an inhibitor of acyl-CoA:cholesterol acyltransferase enzyme. Biochem. Biophys. Res. Commun. 277,pp.417-422 (Collaboration)
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6.
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2001
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Article
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Asymmetric arrangement of auxiliary subunits of skeletal muscle voltage-gated L-type Ca2+ channel. Biochem. Biophys. Res. Commun. 282,pp.284-291 (Collaboration)
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7.
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2001
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Article
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Co-induction of arginino- succinate synthetase, cationic amino acid transporter-2, and nitric oxide synthase in activated murine microglial cells. Brain Res. Mol. Brain Res. 90,pp.165-173 (Collaboration)
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8.
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2002
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Article
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Adipocytes recognize and degrade oxidized low density lipoprotein through CD36. Biochem. Biophys. Res. Commun. 295,pp.319-323 (Collaboration)
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9.
|
2002
|
Article
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Efficient identification of photolabelled amino acid residues by combining immunoaffinity purification with MS: revealing the semotiadil-binding site and its relevance to binding sites for myristates in domain III of human serum albumin Biochem. J. 363,pp.223-232 (Collaboration)
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10.
|
2003
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Article
|
Advanced glycation end products (AGE) inhibit scavenger receptor class B type I-mediated reverse cholesterol transport: a new crossroad of AGE to cholesterol metabolism. J. Atheroscler. Thromb. 10,pp.1-6 (Collaboration)
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11.
|
2003
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Article
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CD36-mediated endocytic uptake of advanced glycation end products (AGE) in mouse 3T3-L1 and human subcutaneous adipocytes. FEBS Lett. 537,pp.85-90 (Collaboration)
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12.
|
2003
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Article
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Cloning, expression and tissue distribution of a tetrameric form of pig carbonyl reductase. Chem. Biol. Interact. 143-144,pp.353-361 (Collaboration)
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13.
|
2003
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Article
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Molecular assembly and subcellular distribution of ATP-sensitive potassium channel proteins in rat hearts. FEBS Lett. 552,pp.259-263 (Collaboration)
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14.
|
2003
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Article
|
Photochemical identification of the binding region for (S)-semotiadil on sodium channels: comparison with that for (R)-semotiadil on skeletal muscle calcium channel. Heterocycles 59,pp.613-622 (Collaboration)
|
15.
|
2004
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Article
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Advanced glycation end products- modified proteins and oxidized LDL mediate down-regulation of leptin in mouse adipocytes via CD36. Biochem. Biophys. Res. Commun. 325,pp.151-156 (Collaboration)
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16.
|
2005
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Article
|
Characterization of benzodiazepine binding site on human a1-acid glycoprotein using flunitrazepam as a photolabeling agent. Biochim. Biophys. Acta 1725,pp.385-393 (Collaboration)
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17.
|
2005
|
Article
|
Proteasomal degradation of Kir6.2 channel protein and its inhibition by a Na+ channel blocker aprindine. Biochem. Biophys. Res. Commun. 331,pp.1001-1006 (Collaboration)
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18.
|
2005
|
Article
|
Stoichiometry and binding site analysis of ligand-human serum albumin complex by photoaffinity labeling and mass spectrometry. J. Mass Spectrom. Soc. Jpn. 53,pp.18-24 (Collaboration)
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19.
|
2006
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Article
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Ligand-directed surface profiling of human cancer cells with combinatorial peptide libraries. Cancer Res. 66,pp.34-40 (Collaboration)
|
20.
|
2007
|
Article
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A previously unrecognized protein-protein interaction between TWEAK and CD163: Potential biological implications. J. Immunol. 178,pp.8183-8194 (Collaboration)
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21.
|
2008
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Article
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Combinatorial targeting of the macropinocytotic pathway in leukemia and lymphoma cells. J. Biol. Chem. 283,pp.11752-11762 (Collaboration)
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22.
|
2008
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Article
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Constitutive overexpression of P-glycoprotein, rather than breast cancer resistance protein or organic cation transporter 1, contributes to acquisition of imatinib-resistance in K562 cells. Pharm. Res. 25,pp.827-835 (Collaboration)
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23.
|
2009
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Article
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A synthetic approach to develop peptide inhibitors selective for brain-type sodium channels on the basis of pompilidotoxin structure. Heterocycles 79,pp.925-933 (Collaboration)
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24.
|
2009
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Article
|
Linkage between phosphorylation of the origin recognition complex and its ATP-binding activity in Saccharomyces cerevisiae. J. Biol. Chem. 284,pp.3396-3407 (Collaboration)
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25.
|
2009
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Article
|
Marked induction of inducible nitric oxide synthase and tumor necrosis factor-α in rat CD40+ microglia by comparison to CD40 microglia. J. Neuroimmunol. 208,pp.70-79 (Collaboration)
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26.
|
2009
|
Article
|
Oral administration of synthetic retinoid Am80(Tamibarotene) decreases brain β-amyloid peptides in APP23 mice. Biol. Pharm. Bull. 32,pp.1307-1309 (Collaboration)
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27.
|
2010
|
Article
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Contribution of BCR-ABL-independent activation of ERK1/2 to acquired imatinib resistance in K562 chronic myeloid leukemia cells. Cancer Sci. 101,pp.137-142 (Collaboration)
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28.
|
2010
|
Article
|
Interconversion between pure chemotactic ligands and chemoattractant/secretagogue ligands of neutrophil C5a receptor by a single amino acid substitution. J. Leukoc. Biol. 87,pp.965-975 (Collaboration)
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29.
|
2010
|
Article
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Three-dimensional structure of α1-β complex in skeletal muscle dihydropyridine receptor by single particle electron microscopy. J. Electron Microsc. 59,pp.215-226 (Collaboration)
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30.
|
2010/02
|
Article
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Notch-1 fragment peptide induces autophagy and caspase-independent cell death in leukemia cell lines An AACR special conference series: Cell Death Mechanisms and Cancer Therapy pp.71 (Collaboration)
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31.
|
2010/10
|
Article
|
Cell-selective cell penetrating peptide as an intelligent molecular carrier BIT 1st Annual World Congress of NanoMedicine-2010 (Collaboration)
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32.
|
2011
|
Article
|
Oxidized LDL and lysophosphatidylcholine stimulate plasminogen activator inhibitor-1 expression through reactive oxygen species generation and ERK1/2 activation in 3T3-L1 adipocytes. Biochim. Biophys. Acta 1811,pp.153-162 (Collaboration)
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33.
|
2011
|
Article
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Quantitative analysis of cysteine-34 on the aniti-oxidative properties of human serum albumin in hemodialysis patients J. Pharm. Sci. 100,pp.3968-3976 (Collaboration)
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34.
|
2011
|
Article
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Targeting neuropilin-1 in human leukemia and lymphoma. Blood 117,pp.920-927 (Collaboration)
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35.
|
2012
|
Article
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Effects of C4a on chemoattractant and secretagogue functions of the other anaphylatoxins via Gi protein-adenylyl cyclase inhibition pathway in mast cells. Int. Immunopharmacol. 12,pp.158-68 (Collaboration)
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36.
|
2012/02
|
Article
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A hybrid peptide-25mer induces a caspase-independent cell death in leukemic cell lines Cell Death in Cancer pp.21 (Collaboration)
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37.
|
2013
|
Article
|
Crystallization and preliminary X-ray analysis of human MTH1 with a homogeneous N-terminus Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 69,pp.45-48 (Collaboration)
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38.
|
2014
|
Article
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Cooperative therapeutic action of retinoic Acid receptor and retinoid X receptor agonists in a mouse model of Alzheimer's disease. J. Alzheimers Dis. 42,pp.587-605 (Collaboration)
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39.
|
2014/07
|
Article
|
Hybrid peptide tat-Ram13-induced necrosis-like cell death depends on expression of PTEN in human leukemia cell lines. Eur. J. Cancer 50,pp.23-24 (Collaboration)
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40.
|
2015
|
Article
|
Targeting interleukin-11 receptor in leukemia and lymphoma: A functional ligand-directed study and hematopathology analysis of patient-derived specimens. Clin. Cancer Res. 21(13),pp.3041-3051 (Collaboration)
|
41.
|
2016/11
|
Article
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The novel monoclonal antibody 9F5 reveals expression of a fragment of GPNMB/osteoactivin processed by furin-like protease(s) in a subpopulation of microglia in neonatal rat brain. Glia 64(11),pp.1938-1961 (Collaboration)
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42.
|
2017
|
Book
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Combination of Photoaffinity Label and Site-Directed Antibody for Target Proteins Photoaffinity Labeling for Structural Probing Within Protein pp.93-110 (Collaboration)
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43.
|
2018/05
|
Article
|
Design and tuning of a cell-penetrating albumin derivative as a versatile nanovehicle for intracellular drug delivery. J Control Release 10(277),pp.23-34 (Collaboration)
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44.
|
2018/05
|
Article
|
The role of vimentin in the tumor marker Nup88-dependent multinucleated phenotype. BMC Cancer 18(1),pp.519 (Collaboration)
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45.
|
2018/05
|
Article
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Therapeutic targeting of membrane-associated GRP78 in leukemia and lymphoma: preclinical efficacy in vitro and formal toxicity study of BMTP-78 in rodents and primates. Pharmacogenomics J. 18(3),pp.436-443 (Collaboration)
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Display 5 items
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Display all(45)
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■ Academic conference presentation
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■ Academic background
1. |
1983/04~1987/03
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Faculty of Pharmaceutical Science, Hokkaido University, Graduated,
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2. |
1987/04~1989/03
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〔Master Course〕, Graduate School, Division of Pharmaceutical Sciences, Hokkaido University, Completed,
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3. |
1990/04~1993/03
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〔Doctorial Course〕, Graduate School of Pharmaceutical Sciences, Hokkaido University, Accomplished credits for doctoral program, Ph.D.
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■ Business career
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■ Belonging society
1.
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2013/10~
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European Association for Cancer Research
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2.
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2018/07~
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American Chemical Society
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3.
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American Association for Cancer Research
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4.
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Society for Neuroscience
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■ Research topic, funded research, and department laboratory expense
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■ E-Mail Address
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■ Present specialized field
Others, Bio chemistry, Pathological biochemistry
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■ Department laboratory expense researcher number
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