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    (Last updated : 2022-06-27 15:37:27)
  LIU Xiaohui
   Department   SOJO UNIVERSITY  Department of Biotechnology and Life Sciences, FACULTY OF BIOTECHNOOLOGY AND LIFE SCIENCE
   SOJO UNIVERSITY  Department of Applied Microbial Technology, FACULTY OF BIOTECHNOOLOGY AND LIFE SCIENCE
   Position  
■ Book and thesis
1. 2021/11 Article Direct evidence of edge-to-face CH/π interaction for PAR-1 thrombin receptor activation Bioorganic & Medicinal Chemistry 51,pp.116498 (Collaboration)  Link
2. 2021/04 Article ERα-agonist and ERβ-antagonist bifunctional next-generation bisphenols with no halogens: BPAP, BPB, and BPZ Toxicology Letters 345,pp.24-33 (Collaboration)  Link
3. 2021/02 Article Bisphenol-C is the strongest bifunctional ERα-agonist and ERβ-antagonist due to magnified halogen bonding PLoS ONE 16(2),pp.e0246583 (Collaboration)  Link
4. 2020/02 Article Evaluation of the influence of halogenation on the binding of bisphenol A to the estrogen-related receptor γ Chemical Research in Toxicology 33(4),pp.889-902 (Collaboration)  Link
5. 2019/12 Article Bisphenol AF: Halogen bonding is a major driving force for the dual ERα-agonist and ERβ-antagonist activities Bioorganic & Medicinal Chemistry 28(3),pp.115274 (Collaboration)  Link
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■ Academic conference presentation
1. 2022/06/14 London dispersion forces as driving force for the ERβ antagonist activity of ERα-agonist next-generation bisphenols
2. 2021/11/04 Halogen-bonding is not necessarily the reason of ERα-agonist and ERβ-antagonist bifunctional activities: ERα/ERβ-heterobifunctionality of hydrocarbon-group-containing next-generation bisphenols
3. 2020/09/14 London dispersion force acting between bisphenol-halogen atoms and estrogen receptors causes a strong functional ERα-agonist / ERβ-antagonist activities
4. 2019/12/12 Evaluation of binding affinity of next generation bisphenols for 21 human nuclear receptors
5. 2019/09/19 Binding affinity of next generation bisphenols for human nuclear receptors
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■ Academic background
1. 2003/04~2005/03 〔Master Course〕, Graduate School, Division of Natural Science, Kyushu University, Completed,
2. 2005/04~2008/03 〔Doctorial Course〕, Graduate School, Division of Natural Science, Kyushu University, Completed,
■ Business career
1. 2013/04~2019/03 Assistant Professor
2. 2019/04~ Graduate School of Engineering /(DC)Division of Applied Microbial Technology
3. 2019/04~ Graduate School of Engineering /Division of Applied Microbial Technology
4. 2019/04~ SOJO UNIVERSITY FACULTY OF BIOTECHNOOLOGY AND LIFE SCIENCE Department of Applied Microbial Technology
■ researchmap Researcher code
B000321189
■ E-Mail Address
  kyoin_mail
■ Research Field
1. 2013/11 日本ペプチド学会 APIPS2013[第4回アジア-太平洋国際ペプチドシンポジウム4th APIPS/第50回ペプチド討論会]優秀ポスター賞 (Constitutive α-helix-peptides required for functional dimerization of estrogen-related receptor γ (ERRγ))
2. 2011/07 日本生化学会 平成23年度日本生化学会-欧文誌JB (Journal of Biochemistry) 論文賞 (istinction of the binding modes for human nuclear receptor ERRγ between bisphenol A and 4-hydroxytamoxifen.)
■ Present specialized field
Chemical substance influence on environment, Others, Molecular biology, Functional biochemistry 
■ Department laboratory expense researcher number
60596849