イケダ ツヨシ   Ikeda Tsuyoshi
  池田 剛
   所属   崇城大学  薬学部 薬学科
   崇城大学大学院  薬学研究科 薬学専攻
   職種   教授
言語種別 英語
発行・発表の年月 2008/01
形態種別 原著論文
査読 査読有り
標題 Two new lignan glucosides from the fruit of Vitex cannabifolia.
執筆形態 共著
掲載誌名 Journal of natural medicines
掲載区分国外
巻・号・頁 62(1),pp.47-51
著者・共著者 Yamasaki Toru, Kawabata Tetsuro, Masuoka Chikako, Kinjo Junei, Ikeda Tsuyoshi, Nohara Toshihiro, Ono Masateru
概要 Two new phenyldihydronaphthalene-type lignan glucosides, vitecannasides A (1) and B (2) were isolated from the fruit of Vitex cannabifolia Sieb. et. Zucc. (Verbenaceae) along with the six known lignan derivatives (3-8), four known iridoid glucosides (9-12), three known flavonoids (13-15), and one known phenylbutanone glucoside (16). Their chemical structures were determined on the basis of spectroscopic data as well as chemical evidence. The scavenging effect of 1, 2, and 11-16 on the stable free radical 1,1-diphenyl-2-picrylhydrazyl was examined. Compounds 1, 2, 14, and 15 exhibited stronger activity than that of L: -cysteine. Especially, 14 and 15 showed more potent activity than that of alpha-tocopherol.
DOI 10.1007/s11418-007-0184-1
ISSN 1861-0293
PMID 18404341