Ikeda Tsuyoshi
   Department   SOJO UNIVERSITY  Department of Pharmaceutical Sciences, FACULTY OF PHARMACEUTICAL SCIENCES
     /(DC)Division of Pharmaceutical Sciences,
Language English
Publication Date 2013/08
Peer Review Peer reviewed
Title Identification and biological activity of antifungal saponins from shallot ( Allium cepa L. Aggregatum group).
Contribution Type
Journal Journal of agricultural and food chemistry
Journal TypeAnother Country
Volume, Issue, Page 61(31),pp.7440-5
Author and coauthor Teshima Yoshiki, Ikeda Tsuyoshi, Imada Kiyoshi, Sasaki Kazunori, El-Sayed Magdi A, Shigyo Masayoshi, Tanaka Shuhei, Ito Shin-Ichi
Details Two major antifungal compounds purified were determined to be alliospiroside A (ALA) and alliospiroside B. ALA had prominent antifungal activity against a wide range of fungi. The products of acid hydrolysis of ALA showed a reduced antifungal activity, suggesting that the compound's sugar chain is essential for its antifungal activity. Fungal cells treated with ALA showed rapid production of reactive oxygen species. The fungicidal action of ALA was partially inhibited by a superoxide scavenger, Tiron, suggesting that superoxide anion generation in the fungal cells may be related to the compound's action. Inoculation experiments showed that ALA protected strawberry plants against Colletotrichum gloeosporioides , indicating that ALA has the potential to control anthracnose of the plant.
DOI 10.1021/jf401720q
ISSN 1520-5118
PMID 24138065