イケダ ツヨシ   Ikeda Tsuyoshi
  池田 剛
   所属   崇城大学  薬学部 薬学科
   崇城大学大学院  薬学研究科 薬学専攻
   職種   教授
言語種別 英語
発行・発表の年月 2013/08
形態種別 原著論文
査読 査読有り
標題 Identification and biological activity of antifungal saponins from shallot ( Allium cepa L. Aggregatum group).
執筆形態 共著
掲載誌名 Journal of agricultural and food chemistry
掲載区分国外
巻・号・頁 61(31),pp.7440-5
著者・共著者 Teshima Yoshiki, Ikeda Tsuyoshi, Imada Kiyoshi, Sasaki Kazunori, El-Sayed Magdi A, Shigyo Masayoshi, Tanaka Shuhei, Ito Shin-Ichi
概要 Two major antifungal compounds purified were determined to be alliospiroside A (ALA) and alliospiroside B. ALA had prominent antifungal activity against a wide range of fungi. The products of acid hydrolysis of ALA showed a reduced antifungal activity, suggesting that the compound's sugar chain is essential for its antifungal activity. Fungal cells treated with ALA showed rapid production of reactive oxygen species. The fungicidal action of ALA was partially inhibited by a superoxide scavenger, Tiron, suggesting that superoxide anion generation in the fungal cells may be related to the compound's action. Inoculation experiments showed that ALA protected strawberry plants against Colletotrichum gloeosporioides , indicating that ALA has the potential to control anthracnose of the plant.
DOI 10.1021/jf401720q
ISSN 1520-5118
PMID 24138065