Ikeda Tsuyoshi
   Department   SOJO UNIVERSITY  Department of Pharmaceutical Sciences, FACULTY OF PHARMACEUTICAL SCIENCES
     /(DC)Division of Pharmaceutical Sciences,
Language English
Publication Date 2013/06
Peer Review Peer reviewed
Title Corosolic acid impairs tumor development and lung metastasis by inhibiting the immunosuppressive activity of myeloid-derived suppressor cells.
Contribution Type
Journal Molecular nutrition & food research
Journal TypeAnother Country
Volume, Issue, Page 57(6),pp.1046-54
Author and coauthor Horlad Hasita, Fujiwara Yukio, Takemura Kenichi, Ohnishi Koji, Ikeda Tsuyoshi, Tsukamoto Hirotake, Mizuta Hiroshi, Nishimura Yasuharu, Takeya Motohiro, Komohara Yoshihiro
Details CONCLUSION:Since Stat3 is associated with tumor progression not only in osteosarcoma, but also in other malignant tumors, our findings indicate that CA might be widely useful in anticancer therapy by targeting the immunosuppressive activity of MDSC and through its synergistic effects with anticancer agents.
DOI 10.1002/mnfr.201200610
ISSN 1613-4133
PMID 23417831