スギウラ マサハル   Sugiura Masaharu
  杉浦 正晴
   所属   崇城大学  薬学部 薬学科
   崇城大学大学院  薬学研究科 薬学専攻
   職種   教授
言語種別 英語
発行・発表の年月 2012/08
形態種別 原著論文
査読 査読有り
標題 Enantioselective reductive aldol reaction using tertiary amine as hydride donor
執筆形態 共著
掲載誌名 Tetrahedron Letters
掲載区分国外
巻・号・頁 53,pp.4199-4201
著者・共著者 Kazuki Osakama, Masaharu Sugiura, Makoto Nakajima, Shunsuke Kotani
概要 An efficient method was developed for the enantioselective reductive aldol reaction of α,β-unsaturated ketones with aldehydes in the presence of a Lewis base catalyst; conjugate reduction using a tertiary amine and trichlorosilyl triflate, followed by an aldol reaction with BINAP dioxide (BINAPO) as an organocatalyst, gave the corresponding product in high yield with high stereoselectivity. © 2012 Elsevier Ltd. All rights reserved.
DOI 10.1016/j.tetlet.2012.05.147
ISSN 00404039
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