スギウラ マサハル   Sugiura Masaharu
  杉浦 正晴
   所属   崇城大学  薬学部 薬学科
   崇城大学大学院  薬学研究科 薬学専攻
   職種   教授
言語種別 英語
発行・発表の年月 2008/10
形態種別 原著論文
査読 査読有り
標題 Lewis Base-catalyzed Conjugate Reduction and Reductive Aldol Reaction of α,β-Unsaturated Ketones Using Trichlorosilane
執筆形態 共著
掲載誌名 Chem. Commun.
掲載区分国外
巻・号・頁 pp.4309-4311
著者・共著者 M. Sugiura, N. Sato, S. Kotani, M. Nakajima
概要 Lewis bases such as Ph3P=O and HMPA catalyze the 1,4-reduction of α,β-unsaturated ketones with trichlorosilane, and because the 1,2-reduction of aldehydes scarcely proceeded under the conditions, one-pot reductive aldol reactions with aldehydes were successfully achieved; preliminary studies using a chiral Lewis base revealed a high potential for enantioselective catalysis. © The Royal Society of Chemistry.
DOI 10.1039/b807529h
ISSN 13597345
PMID 18802553
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