スギウラ マサハル   Sugiura Masaharu
  杉浦 正晴
   所属   崇城大学  薬学部 薬学科
   崇城大学大学院  薬学研究科 薬学専攻
   職種   教授
言語種別 英語
発行・発表の年月 2006/01
形態種別 原著論文
標題 Highly selective formation of propargyl- and allenyltrichlorosilanes and their regiospecific addition to various types of aldehydes: Preparation of both allenic and homopropargylic alcohols
執筆形態 共著
掲載誌名 Tetrahedron
掲載区分国外
巻・号・頁 62,pp.496-502
著者・共著者 Uwe Schneider, Masaharu Sugiura, Shu Kobayashi
概要 The highly selective preparation of propargyl- and allenyltrichlorosilanes via metal-catalyzed silylation of propargyl chloride has been developed. These trichlorosilyl nucleophiles were then shown to add to various types of aldehydes to afford the corresponding allenic and homopropargylic alcohols, respectively, in high yields with complete regiospecificity. Remarkably, these carbon-carbon bond-forming reactions simply proceeded in N,N-dimethylformamide (DMF) without using any metal catalysts. © 2005 Elsevier Ltd. All rights reserved.
DOI 10.1016/j.tet.2005.08.114
ISSN 00404020
PermalinkURL https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=28944440168&origin=inward