スギウラ マサハル   Sugiura Masaharu
  杉浦 正晴
   所属   崇城大学  薬学部 薬学科
   崇城大学大学院  薬学研究科 薬学専攻
   職種   教授
言語種別 英語
発行・発表の年月 2005/12
形態種別 原著論文
査読 査読有り
標題 Cyanation of N-acylhydrazones with trimethylsilyl cyanide promoted by a Brønsted base and a Lewis acid
執筆形態 共著
掲載誌名 Advanced Synthesis and Catalysis
掲載区分国外
巻・号・頁 347,pp.1899-1903
著者・共著者 Hideyuki Konishi, Chikako Ogawa, Masaharu Sugiura, Shu Kobayashi
概要 Cyanation of N-acylhydrazones using trimethylsilyl cyanide (TMSCN) proceeded well in the presence of an amine to afford the corresponding α-hydrazinonitriles in high yields. For less reactive substrates, the combined use of an amine and a catalytic amount of scandium triflate [Sc(OTf)3] was effective to promote the reactions. The mechanistic study suggested that the amine worked as a Brønsted base. © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.
DOI 10.1002/adsc.200505272
ISSN 16154150
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