スギウラ マサハル   Sugiura Masaharu
  杉浦 正晴
   所属   崇城大学  薬学部 薬学科
   崇城大学大学院  薬学研究科 薬学専攻
   職種   教授
言語種別 英語
発行・発表の年月 2004/08
形態種別 総説
査読 査読有り
標題 Neutral Coordinate-organocatalysts in Organic Synthesis. Allylation of Acylhydrazones with Allyltrichlorosilanes
執筆形態 共著
掲載誌名 Adv. Synth. Cat.
掲載区分国外
巻・号・頁 346,pp.1023-1023
著者・共著者 S. Kobayashi, M. Sugiura, C. Ogawa
概要 N,N-Dimethylformamide (DMF), sulfoxides, and phosphine oxides, etc., which are neutral, uncharged molecules and coordinate to silicon atoms of organosilicon reagents to activate nucleophilic addition, are defined as neutral coordinate-organocatalysts (NCOs). In the presence of NCOs, allylation reactions of acylhydrazones, useful imine surrogates, using allyltrichlorosilanes proceed smoothly to afford the synthetically useful racemic and non-racemic homoallylic amine derivatives in high yields with high diastereoselectivities.
DOI 10.1002/adsc.200404101
ISSN 16154150
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