Faculty Information - LIU Xiaohui

LIU Xiaohui

Department / Course FACULTY OF BIOTECHNOOLOGY AND LIFE SCIENCE Department of Biotechnology and Life Sciences

Job

Book and thesis
1.	2025/12/27	Papers	Evolution of Sitophilus zeamais (Coleoptera: Curculionidae) in artificial rearing and field conditions. The Journal of Basic and Applied Zoology 86 (116) (Co-authored)
2.	2024/10/21	Papers	The N-terminal activation function AF-1 domain of ERα interacts directly with the C-terminal AF-2-holding ligand-binding domain to recruit the coactivator proteins. PLOS ONE 19 (10),pp.e0312276 (Co-authored)
3.	2021/11	Papers	Direct evidence of edge-to-face CH/π interaction for PAR-1 thrombin receptor activation Bioorganic & Medicinal Chemistry 51,pp.116498 (Co-authored)
4.	2021/04	Papers	ERα-agonist and ERβ-antagonist bifunctional next-generation bisphenols with no halogens: BPAP, BPB, and BPZ. Toxicology Letters 345,pp.24-33 (Co-authored)
5.	2021/02	Papers	Bisphenol-C is the strongest bifunctional ERα-agonist and ERβ-antagonist due to magnified halogen bonding. PLOS ONE 16 (2),pp.e0246583 (Co-authored)
6.	2020/02	Papers	Evaluation of the influence of halogenation on the binding of bisphenol A to the estrogen-related receptor γ. Chemical Research in Toxicology 33 (4),pp.889-902 (Co-authored)
7.	2019/12	Papers	Bisphenol AF: Halogen bonding is a major driving force for the dual ERα-agonist and ERβ-antagonist activities. Bioorganic & Medicinal Chemistry 28 (3),pp.115274 (Co-authored)
8.	2019/07	Papers	Discovery of novel oestrogen receptor α agonists and antagonists by screening a revisited privileged structure moiety for nuclear receptors. Scientific reports 9 (1),pp.9954 (Co-authored)
9.	2019/06	Papers	Receptor-binding affinities of bisphenol A and its next-generation analogs for human nuclear receptors. Toxicology and applied pharmacology 377,pp.114610 (Co-authored)
10.	2019/03	Other	Evaluation of the binding ability of an orphan nuclear receptor nurr1 to synthetic peptides. Peptide Science 2018 2018,pp.133 (Co-authored)
11.	2018/03	Other	Homodimer function of human nuclear receptor ERRγ evidenced using α-helix peptides in the dimer interface. Peptide Science 2017,pp.190-191 (Co-authored)
12.	2018/03	Other	Mutual co-work between nuclear receptor ERα and ERRα requires their homodimerization. Peptide Science 2017,pp.198-199 (Co-authored)
13.	2018/03	Other	Phe271^5.39 of thrombin receptor PAR-1 is a specific target of Phe-2-phenyl group of its tethered ligand. Peptide Science 2017,pp.94-95 (Co-authored)
14.	2017/10	Papers	Design and synthesis of benzoacridines as estrogenic and anti-estrogenic agents. Bioorganic & medicinal chemistry 25 (20),pp.5216-5237 (Co-authored)
15.	2017/08	Papers	α-Helix-peptides composing the human nuclear receptor ERRγ competitively provoke inhibition of functional homomeric dimerization. — Bisphenol A receptor ERRγ physiologically functions as homodimer. Biomedical Advances,pp.ep-20178-10 (Co-authored)
16.	2017/03	Other	Docking simulation to elucidated the labeled cysteine residue of the nociception receptor ORL1 using a Cys(Npys)-containing peptide ligand. Peptide Science 2016,pp.87-88 (Co-authored)
17.	2016/11	Papers	Specific affinity-labeling of the nociceptin ORL1 receptor using a thiol-activated Cys(Npys)-containing peptide ligand. Biopolymers: Peptide Science 106 (4),pp.460-469 (Co-authored)
18.	2016/11	Papers	α-Helix-peptides comprising the human nuclear receptor ERRγ competitively provoke inhibition of functional homomeric dimerization. Biopolymers: Peptide Science 106 (4),pp.547-554 (Co-authored)
19.	2016/03	Other	Comparative analysis of the ligand binding domain secondary structures of human nuclear receptors. Peptide Science 2015,pp.337-338 (Co-authored)
20.	2016/03	Other	Comprehensive structural analysis of the nociception ORL1 receptor by means of virtual and experimental Ala-scanning combinated methods. Peptide Science 2015,pp.149-150 (Co-authored)
21.	2016/03	Other	Do the estrogen receptors function as a homodimer? Experimental validation of homodimerization by inhibitory peptides. Peptide Science 2015,pp.335-336 (Co-authored)
22.	2016/03	Other	Expression analysis of neuropeptide pdf mRNA in the hypoactive and hyperactive fruit flies Drosophila melanogaster. Peptide Science 2015,pp.317-318 (Co-authored)
23.	2016/03	Other	Functional role of the Phe-Phe stacking microswitch in the ORL1 nociceptin receptor activation. Peptide Science 2015,pp.147-148 (Co-authored)
24.	2016/03	Other	ORL1 nociceptin receptor response of opioid peptides derived from proenkephalin precursor protein. Peptide Science 2015,pp.181-182 (Co-authored)
25.	2016/03	Other	Protein constitutive peptide fragments to inhibit protein-protein interaction: Inhibitory peptides as molecular probe for clarification of human nuclear receptor activation mechanism. Peptide Science 2015,pp.319-320 (Co-authored)
26.	2015/03	Other	A novel method to identify and quantify the coactivator proteins that couple with human nuclear receptor: The use of interacting interface α-helix peptide for quantitative inhibition. Peptide Science 2014,pp.349-350 (Co-authored)
27.	2015/03	Other	Bisphenol A-induced substantial peak decay of Drosophila circadian neuropeptide hugin mRNA expression. Peptide Science 2014,pp.41-42 (Co-authored)
28.	2015/03	Other	GPCR functional role of Phe-269 and Phe-221 in the molecular switching of ORL1 nociceptin receptor activation. Peptide Science 2014,pp.203-204 (Co-authored)
29.	2015/03	Other	Structural and molecular evolutionary analysis of the ligand-binding domain of forty-eight human nuclear receptors. Peptide Science 2014,pp.347-348 (Co-authored)
30.	2015/03	Other	The molecular switching of ORL1 nociceptin receptor in activation/ inactivation. Peptide Science 2014,pp.201-202 (Co-authored)
31.	2014/06	Papers	A characteristic back support structure in the bisphenol A-binding pocket in the human nuclear receptor ERRγ. PloS one 9 (6),pp.e101252 (Co-authored)
32.	2014/03	Other	Bisphenol A- induced epigenetic mutations in circadian pacemaker neuropeptide mRNAs of hyperactive Drosophila fruit flies. Peptide Science 2013,pp.457-458 (Co-authored)
33.	2014/03	Other	Constitutive α-helix-peptides required for functional dimerization of estrogen-related receptor γ (ERRγ). Peptide Science 2013,pp.429-430 (Co-authored)
34.	2014/03	Other	Expression and mutation analyses of brain neuropeptide genes of endocrine-disrupting bisphenol A-exposed hypoactive mouse. Peptide Science 2013,pp.453-454 (Co-authored)
35.	2014/03	Other	Influence analysis of the circadian evening pacemaker neuropeptide hugγ gene in the bisphenol A-exposed fruit fly Drosophila brain. Peptide Science 2013,pp.455-456 (Co-authored)
36.	2014/03	Other	Three-dimensional docking modeling to human nuclear receptors for exploration of bisphenol-A targeting receptors. Peptide Science 2013,pp.459-460 (Co-authored)
37.	2013/03	Other	Bisphenol-binding pocket of constitutively active nuclear receptor CAR: Docking modeling for close-packing. Peptide Science 2012,pp.401-402 (Co-authored)
38.	2013/03	Other	The impact of bisphenol A-feeding on the Drosophila neuropeptide PDF mRNA structure. Peptide Science 2012,pp.75-76 (Co-authored)
39.	2012/04	Papers	Fine spatial assembly for construction of the phenol-binding pocket to capture bisphenol A in the human nuclear receptor estrogen-related receptor γ. Journal of biochemistry 151 (4),pp.403-415 (Co-authored)
40.	2010/09	Papers	Bisphenol AF is a full agonist for the estrogen receptor ERalpha but a highly specific antagonist for ERbeta. Environmental health perspectives 118 (9),pp.1267-1272 (Co-authored)
41.	2010/08	Papers	Distinction of the binding modes for human nuclear receptor ERRgamma between bisphenol A and 4-hydroxytamoxifen. Journal of biochemistry 148 (2),pp.247-254 (Co-authored)
42.	2010/03	Other	Functional role of the C-terminal helix 12 peptide in the receptor activation mechanism of estrogen-related receptor γ (ERRγ). Peptide Science 2009,pp.435-436 (Co-authored)
43.	2009/07	Papers	Placenta expressing the greatest quantity of bisphenol A receptor ERR{gamma} among the human reproductive tissues: Predominant expression of type-1 ERRgamma isoform. Journal of biochemistry 146 (1),pp.113-122 (Co-authored)
44.	2009/03	Other	Bisphenol A-specific nuclear receptor ERRγ: Structure-function analysis of the two novel isoforms lacking vital peptide fragment in the ligand binding domain. Peptide Science 2008,pp.517-518 (Co-authored)
45.	2009/03	Other	Induced-fit type ligand binding guided by free-rotatory Leu residue present in the 7th α-helix peptide in the estrogen-related receptor γ (ERRγ). Peptide Science 2008,pp.521-522 (Co-authored)
46.	2008/08	Papers	ERRgamma tethers strongly bisphenol A and 4-alpha-cumylphenol in an induced-fit manner. Biochemical and biophysical research communications 373 (3),pp.408-413 (Co-authored)
47.	2008/03	Other	The conformation change-sensing antibodies for retinoid-related orphan receptor family. Peptide Science 2007,pp.491-492 (Co-authored)
48.	2008/01	Papers	Direct evidence revealing structural elements essential for the high binding ability of bisphenol A to human estrogen-related receptor-gamma. Environmental health perspectives 116 (1),pp.32-38 (Co-authored)
49.	2007/12	Papers	Receptor binding characteristics of the endocrine disruptor bisphenol A for the human nuclear estrogen-related receptor gamma. Chief and corroborative hydrogen bonds of the bisphenol A phenol-hydroxyl group with Arg316 and Glu275 residues. The FEBS journal 274 (24),pp.6340-6351 (Co-authored)
50.	2007/10	Papers	Structural evidence for endocrine disruptor bisphenol A binding to human nuclear receptor ERR gamma. Journal of biochemistry 142 (4),pp.517-524 (Co-authored)
51.	2007/03	Other	Conformation change of α-helix peptide for sensing of deactivation of nuclear receptor: Immunoassay using polyclonal antibody specific for the C-terminal α-helix 12 of estrogen-related receptor γ (ERRγ). Peptide Science 2006,pp.176 (Co-authored)
52.	2006/12	Papers	Endocrine disruptor bisphenol A strongly binds to human estrogen-related receptor gamma (ERRgamma) with high constitutive activity. Toxicology letters 167 (2),pp.95-105 (Co-authored)
53.	2005/03	Other	Structural characteristics of Drosophila estrogen-related receptor ligand binding domain to capture the peptide and non-peptide ligands. Peptide Science 2004,pp.303-304 (Co-authored)
54.	2004/04/26	Papers	Molecular cloning and circadian expression profile of insect neuropeptide PDF in black blowfly, Phormia regina. Letter in Peptide Science 10,pp.419-430 (Co-authored)