Faculty Information - Nishi Kouji

Nishi Kouji

Department / Course FACULTY OF PHARMACEUTICAL SCIENCES Department of Pharmaceutical Sciences

Job

Book and thesis
1.	2022	Papers	Study of the inclusion complexes formed between 4-phenylbutyrate and α-, β- and γ-cyclodextrin in solution and evaluation on their taste-masking properties. J Pharm Pharmacol. (Co-authored)
2.	2022/03	Papers	The Nitrated Form of Nateglinide Induces Apoptosis in Human Pancreatic Cancer Cells Through a Caspase-dependent Mechanism. Anticancer Res. 42 (3),pp.1333-1338 (Co-authored)
3.	2022/03	Papers	In Vitro and In Vivo Assessment of Atemoya Fruit (Annona atemoya) for Food-Drug Interactions. Eur J Drug Metab Pharmacokinet. 47 (2),pp.177-185 (Co-authored)
4.	2022/01	Papers	Effects of Myristate on the Induced Circular Dichroism Spectra of Aripiprazole Bound to Human Serum Albumin: A Structural-Chemical Investigation. ACS Omega. 7 (5),pp.4413-4419 (Co-authored)
5.	2022/01	Papers	An in-vitro comparative study of the binding of caspofungin and micafungin to plasma proteins. J Pharm Pharmacol. 74 (5),pp.88-93 (Co-authored)
6.	2021/11	Papers	The Binding of Aripiprazole to Plasma Proteins in Chronic Renal Failure Patients. Toxins 13 (18),pp.1813 (Co-authored)
7.	2021	Papers	Effects of Uremic Toxins on the Binding of Aripiprazole to Human Serum Albumin Biol Pharm Bull. (Co-authored)
8.	2021	Papers	Possible Role of Electrolytes on the Formation of Precipitates during the Infusion of Nafamostat Mesilate in Hemodialysis. Biol Pharm Bull. (Co-authored)
9.	2021	Papers	Interaction of Benzbromarone with Subdomains IIIA and IB/IIA on Human Serum Albumin as the Primary and Secondary Binding Regions. Mol Pharm (Co-authored)
10.	2021	Papers	Synthesis and In Vitro Assessment of pH-Sensitive Human Serum Albumin Conjugates of Pirarubicin. Pharmaceuticals (Co-authored)
11.	2020	Papers	Characterization of Bovine Lactoferrin Nanoparticle Prepared by Desolvation Technique. Chem Pharm Bull (Co-authored)
12.	2020	Papers	Characterization of the Interaction of Daptomycin With Site II on Human Serum Albumin. J Pharm Sci. (Co-authored)
13.	2020	Papers	Effects of Oxidation of Human Serum Albumin on the Binding of Aripiprazole. Biol Pharm Bull. (Co-authored)
14.	2020/05	Papers	Structural insights into the inhibition mechanism of human sterol O-acyltransferase 1 by a competitive inhibitor. Nat Commun. 11 (18),pp.2478 (Co-authored)
15.	2020	Papers	Serum Albumin, Lipid and Drug Binding Subcell Biochem 94,pp.383-397 (Co-authored)
16.	2019/12	Papers	Processing grapefruit juice with γ-cyclodextrin attenuates its inhibitory effect on cytochrome P450 3A activity. (Co-authored)
17.	2019/12	Papers	Interaction of Aripiprazole With Human α1-Acid Glycoprotein. J Pharm Sci. (Co-authored)
18.	2019/11	Papers	Enhanced dissolution and oral bioavailability of praziquantel by emulsification with human serum albumin followed by spray drying. Eur J Pharm Sci. (Co-authored)
19.	2019/11	Papers	α1-Acid Glycoprotein Has the Potential to Serve as a Biomimetic Drug Delivery Carrier for Anticancer Agents. J Pharm Sci. (Co-authored)
20.	2019/06	Papers	Investigation of anti-tumor effect of doxorubicin-loaded human serum albumin nanoparticles prepared by a desolvation technique. Cancer Chemother Pharmacol. (Co-authored)
21.	2019/05	Papers	Further Evidence Regarding the Important Role of Chlorine Atoms of Aripiprazole on Binding to the Site II Area of Human Albumin. J Pharm Sci. (Co-authored)
22.	2019/02	Papers	Apoptosis Induced by Ultraviolet A Exposure in the Presence of Enoxacin in HL-60 Cells. Anticancer Res. (Co-authored)
23.	2018/12	Papers	Glutamine Deprivation Enhances Acetyl-CoA Carboxylase Inhibitor-induced Death of Human Pancreatic Cancer Cells. Anticancer Res. (Co-authored)
24.	2018/07	Papers	Metal-catalyzed oxidation of human serum albumin does not alter the interactive binding to the two principal drug binding sites. Biochemistry and biophysics reports 14,pp.155-160 (Co-authored)
25.	2018/03	Papers	Effect of endogenous substances on the binding of sodium 4-phenylbutyrate to human serum albumin. Acta Chim Pharm Indica (Co-authored)
26.	2017/12	Papers	Interaction of Protizinic Acid with Human Serum Albumin: Site-to-Site Displacement of Protizinic Acid by Ibuprofen. Acta Chim Pharm Indica (Co-authored)
27.	2017/11	Papers	Photodynamically-induced Apoptosis Due to Ultraviolet A in the Presence of Lomefloxacin in Human Promyelocytic Leukemia Cells. Anticancer research 37 (11),pp.6407-6413 (Co-authored)
28.	2017/11	Papers	Enoxacin with UVA Irradiation Induces Apoptosis in the AsPC1 Human Pancreatic Cancer Cell Line Through ROS Generation. Anticancer research 37 (11),pp.6211-6214 (Co-authored)
29.	2017/09	Papers	Recombinant Human Serum Albumin Containing 3 Copies of Domain I, Has Significant in Vitro Antioxidative Capacity Compared to the Wild-Type. Biological & pharmaceutical bulletin 40 (10),pp.1813-1817 (Co-authored)
30.	2017/06	Papers	Long chain fatty acids alter the interactive binding of ligands to the two principal drug binding sites of human serum albumin. PloS one 12 (6),pp.e0180404 (Co-authored)
31.	2016/09	Papers	Inhibition of Fatty Acid Synthesis Induces Apoptosis of Human Pancreatic Cancer Cells. Anticancer research 36 (9),pp.4655-60 (Co-authored)
32.	2016/05	Papers	Antitumor effect of sonodynamically activated pyrrolidine tris-acid fullerene. (Co-authored)
33.	2015/06	Papers	Apoptosis induction by aluminum phthalocyanine tetrasulfonate-based sonodynamic therapy in HL-60 cells. Jpn J Appl Phys. (Co-authored)
34.	2014/11	Papers	Involvement of reactive oxygen species in the enhancement of membrane lipid peroxidation by sonodynamic therapy with functionalized fullerenes. Anticancer research 34 (11),pp.6481-7 (Co-authored)
35.	2014/04	Papers	Acyl-coenzyme A:cholesterol acyltransferase 1 - significance of single-nucleotide polymorphism at residue 526 and the role of Pro347 near the fifth transmembrane domain. The FEBS journal 281 (7),pp.1773-83 (Co-authored)
36.	2013/08	Papers	Sonodynamically-induced anticancer effects by functionalized fullerenes. Anticancer research 33 (8),pp.3145-51 (Co-authored)
37.	2013	Papers	Molecular Aspects of Human Alpha-1 Acid Glycoprotein - Structure and Function. Acute Phase Proteins INTECH. Acute phase protein (Co-authored)
38.	2012/09	Papers	Involvement of reactive oxygen species in sonodynamically induced apoptosis using a novel porphyrin derivative. Theranostics 2 (9),pp.880-8 (Co-authored)
39.	2012/04	Papers	Characterization of the hepatic cellular uptake of α(1) -acid glycoprotein (AGP), part 1: a peptide moiety of human AGP is recognized by the hemoglobin β-chain on mouse liver parenchymal cells. Journal of pharmaceutical sciences 101 (4),pp.1599-606 (Co-authored)
40.	2012/04	Papers	Characterization of hepatic cellular uptake of α1-acid glycoprotein (AGP), part 2: involvement of hemoglobin β-chain on plasma membranes in the uptake of human AGP by liver parenchymal cells. Journal of pharmaceutical sciences 101 (4),pp.1607-15 (Co-authored)
41.	2011/04	Papers	Structural insights into differences in drug-binding selectivity between two forms of human alpha1-acid glycoprotein genetic variants, the A and F1*S forms. The Journal of biological chemistry 286 (16),pp.14427-34 (Co-authored)
42.	2011/02	Papers	Sonodynamically-induced antitumor effect of mono-l-aspartyl chlorin e6 (NPe6). Anticancer research 31 (2),pp.501-6 (Co-authored)
43.	2010/06	Papers	Sonodynamically induced cell damage and membrane lipid peroxidation by novel porphyrin derivative, DCPH-P-Na(I). Anticancer research 30 (6),pp.2241-6 (Co-authored)
44.	2010/02	Papers	Construction of an expression system for human alpha(1)-acid glycoprotein in E. coli: The roles of oligosaccharide moieties in structural and functional properties. Drug metabolism and pharmacokinetics 25 (2),pp.200-7 (Co-authored)
45.	2010/01	Papers	Receptor-mediated uptake of human alpha1-acid glycoprotein into liver parenchymal cells in mice. Drug metabolism and pharmacokinetics 25 (1),pp.101-7 (Co-authored)
46.	2009/11	Papers	A site-directed mutagenesis study of drug-binding selectivity in genetic variants of human alpha(1)-acid glycoprotein. Journal of pharmaceutical sciences 98 (11),pp.4316-26 (Co-authored)
47.	2007/11	Papers	Structural and ligand-binding properties of serum albumin species interacting with a biomembrane interface. Journal of pharmaceutical sciences 96 (11),pp.3117-24 (Co-authored)
48.	2007/07	Papers	Alpha1-acid glycoprotein suppresses rat acute inflammatory paw edema through the inhibition of neutrophils activation and prostaglandin E2 generation. Biological & pharmaceutical bulletin 30 (7),pp.1226-30 (Co-authored)
49.	2006/05	Papers	Involvement of disulfide bonds and histidine 172 in a unique beta-sheet to alpha-helix transition of alpha 1-acid glycoprotein at the biomembrane interface. Proteins 63 (3),pp.611-20 (Co-authored)
50.	2005/10	Papers	Characterization of benzodiazepine binding site on human alpha1-acid glycoprotein using flunitrazepam as a photolabeling agent. Biochimica et biophysica acta 1725 (3),pp.385-93 (Co-authored)
51.	2005/07	Papers	Cooperative effect of hydrophobic and electrostatic forces on alcohol-induced alpha-helix formation of alpha1-acid glycoprotein. FEBS letters 579 (17),pp.3596-600 (Co-authored)
52.	2005/02	Papers	Effect of genetic variation on the thermal stability of human serum albumin. Biochimica et biophysica acta 1747 (1),pp.81-8 (Co-authored)
53.	2005/01	Papers	Use of photoaffinity labeling and site-directed mutagenesis for identification of the key residue responsible for extraordinarily high affinity binding of UCN-01 in human alpha1-acid glycoprotein. The Journal of biological chemistry 280 (2),pp.1384-91 (Co-authored)
54.	2004/10	Papers	Construction of expression system for human alpha 1-acid glycoprotein in Pichia pastoris and evaluation of its drug-binding properties. Drug metabolism and disposition: the biological fate of chemicals 32 (10),pp.1069-74 (Co-authored)
55.	2004/09	Papers	Tryptophan residues play an important role in the extraordinarily high affinity binding interaction of UCN-01 to human alpha-1-acid glycoprotein. Pharmaceutical research 21 (9),pp.1648-55 (Co-authored)
56.	2004/08	Papers	Binding of alpha1-acid glycoprotein to membrane results in a unique structural change and ligand release. Biochemistry 43 (32),pp.10513-9 (Co-authored)
57.	2002/12	Papers	Structural and drug-binding properties of alpha(1)-acid glycoprotein in reverse micelles. Biochimica et biophysica acta 1601 (2),pp.185-91 (Co-authored)
58.	2002/12	Papers	Characterization of ligand binding sites on the alpha1-acid glycoprotein in humans, bovines and dogs. Drug metabolism and pharmacokinetics 17 (4),pp.300-6 (Co-authored)
59.	2000/04	Papers	Characterization of a binding site of UCN-01, a novel anticancer drug on alpha-acid glycoprotein (Co-authored)