教員情報 - 杉浦　正晴

スギウラ　マサハル Sugiura Masaharu
杉浦　正晴

所属薬学部薬学科

職種教授

著書・論文歴
1.	2024/01	論文	Conversion of raltegravir carrying a 1,3,4-oxadiazole ring to a hydrolysis product upon pH changes decreases its antiviral activity. PNAS nexus 3 (1),pgad446 (共著)
2.	2023/07	論文	Lithium Binaphtholate-Catalyzed Asymmetric Michael Reaction of Acrylamides. Chemical & pharmaceutical bulletin 71 (10),792-797 (共著)
3.	2023/12	論文	Recruitment of hexahydroquinoline as anticancer scaffold targeting inhibition of wild and mutants EGFR (EGFRWT, EGFRT790M, and EGFRL858R). Journal of enzyme inhibition and medicinal chemistry 38 (1),2241674 (共著)
4.	2023/01	論文	Synthesis of Selenoesters via Aldol Condensation and/or Conjugate Reduction and Their Antiviral Activities. ACS omega 8 (1),1369-1374頁 (共著)
5.	2022/10	論文	Synthesis, crystallographic, DNA binding, and molecular docking/dynamic studies of a privileged chalcone-sulfonamide hybrid scaffold as a promising anticancer agent. Journal of biomolecular structure & dynamics,1-15頁 (共著)
6.	2021/05	論文	Aromatic-Turmerone Analogs Protect Dopaminergic Neurons in Midbrain Slice Cultures through Their Neuroprotective Activities. Cells 10 (5) (共著)
7.	2020/10	著書	"Catalysis by Silicon Species (Chapter 11)" In "Catalysis with Earth-abundant Elements",309-333頁 (共著)
8.	2020/09	論文	Synthesis of conjugated multiunsaturated thioesters via one-pot TiCl4-promoted aldol condensation Tetrahedron Letters 61 (36),152280 (共著)
9.	2020/05	論文	O-Monoacyltartaric Acid/(Thio)urea Cooperative Organocatalysis for Enantioselective Conjugate Addition of Boronic Acid. Organic letters 22 (10),3780-3784頁 (共著)
10.	2019/08	論文	Lewis Base-Catalyzed Enantioselective Conjugate Reduction of β,β-Disubstituted α,β-Unsaturated Ketones with Trichlorosilane: E/Z-Isomerization, Regioselectivity, and Synthetic Applications. [Highlighted in Organic Chemistry Portal; Featured in Org. Chem. Highlights: Alkylated Stereogenic Centers] The Journal of Organic Chemistry 84 (18),11458-11473頁 (共著)
11.	2019/06	論文	Selective Monoacylation of Diols and Asymmetric Desymmetrization of Dialkyl meso-Tartrates Using 2-Pyridyl Esters as Acylating Agents and Metal Carboxylates as Catalysts. The Journal of Organic Chemistry 84 (14),9313-9321頁 (共著)
12.	2018/11	論文	Catalytic Enantioselective Aldol Reactions of Unprotected Carboxylic Acids under Phosphine Oxide Catalysis Angewandte Chemie - International Edition 57,15877-15881頁 (共著)
13.	2018/06	論文	Ｏ‐モノアシル酒石酸触媒によるホウ素化合物の活性化有機合成化学協会誌 76 (6),596-603頁 (単著)
14.	2017/10	論文	Stereoselective Synthesis of Nitrogen-Containing Compounds from Enamines. The Journal of organic chemistry 82 (20),10968-10979頁 (共著)
15.	2017/07	論文	Sequential Catalysis of Phosphine Oxide for Stereoselective Synthesis of Stereopentads. Organic letters 19 (13),3672-3675頁 (共著)
16.	2017/01	論文	Enantioselective chlorinative aldol reaction of α-substituted acroleins catalyzed by chiral phosphine oxides Tetrahedron Asymmetry 28 (2),282-287頁 (共著)
17.	2017	論文	Asymmetric Aldol/Vinylogous Aldol/Cyclization Reaction Using Phosphine Oxide Catalysts. Chemical & pharmaceutical bulletin 65 (10),989-993頁 (共著)
18.	2016/02	論文	Concise Asymmetric Construction of C<inf>2</inf>-symmetric 1,9-Diarylnonanoids Using a Hypervalent Silicon Complex: Total Synthesis of (-)-Ericanone Chemistry - An Asian Journal 11,376-379頁 (共著)
19.	2016/02	論文	Stereoselective Synthesis of Highly Functionalized 2,3-Dihydro-4-pyranones Using Phosphine Oxide as Catalyst. Chem. Pharm. Bull. 64 (2),189-192頁 (共著)
20.	2015/08	論文	One-Pot Synthesis of β,β-Disubstituted α,β-Unsaturated Carbonyl Compounds. J. Org. Chem. 80,8830-8835頁 (共著)
21.	2015/08	論文	Conjugate Addition of Diboron Catalyzed by O-Monoacyltartaric Acids. Synthesis 47,2265-2269頁 (共著)
22.	2014/10	論文	O-Monoacyltartaric Acid-Catalyzed Enantioselective Conjugate Addition of a Boronic Acid to Dienones: Application to the Synthesis of Optically Active Cyclopentenones. Org. Lett. 16,5172-5175頁 (共著)
23.	2014/09	論文	Phosphine Oxide-Catalyzed Enantioselective Intramolecular Aldol Reaction via Regioselective Enolization of Unsymmetrical Diketones with Tetrachlorosilane. Org. Lett. 16,4802-4805頁 (共著)
24.	2014/07	論文	Imino ene-type reaction of enamines with N-sulfonylimines and application to diastereoselective synthesis of N-sulfonyl-1,3-diamines Tetrahedron Letters 55,4082-4085頁 (共著)
25.	2014/07	論文	A Hydrogen Bond Rationale for the Enantioselective β-Alkenylboration of Enones Catalyzed by O-Monoacyltartaric Acids. J. Org. Chem. 79,6754-6758頁 (共著)
26.	2014/03	論文	Diastereoselective Synthesis of 1,3-Diamines by a Domino Reaction of Imines, Enamines, and Trichlorosilane. Tetrahedron Lett. 55,1924-1926頁 (共著)
27.	2014/01	論文	Enantioselective Double Aldol Reactions Involving the Sequential Activation of Silicon Tetrachloride by Chiral Phosphine Oxides. Synlett 25,631-640頁 (共著)
28.	2013/12	論文	Atropisomeric chiral dienes in asymmetric catalysis: C<inf>2</inf>- symmetric (Z,Z)-2,3-Bis[1-(diphenylphosphinyl)ethylidene]tetralin as a highly active lewis base organocatalyst Angewandte Chemie - International Edition 52,13798-13802頁 (共著)
29.	2013/11	論文	Enantioselective Morita–Baylis–Hillman Reaction Catalyzed by a Chiral Phosphine oxide. Tetrahedron Lett. 54,6430-6433頁 (共著)
30.	2013/08	論文	Enantioselective aldol reactions catalyzed by chiral phosphine oxides Chemical Record 13,362-370頁 (共著)
31.	2013/04	論文	Facile Synthesis of Chiral 1,2-Chlorohydrins via the Ring-opening of meso-Epoxides Catalyzed by Chiral Phosphine Oxides Tetrahedron 69,3075-3081頁 (共著)
32.	2013/03	論文	Stereoselective Synthesis of Multiple Stereocenters by Using a Double Aldol Reaction Angew. Chem. Int. Ed. 52,3461-3464頁 (共著)
33.	2012/09	論文	6.8 Allylations of C-O and C-N Double Bonds and Related Reactions Comprehensive Chirality 6,214-233頁 (共著)
34.	2012/08	論文	Enantioselective reductive aldol reaction using tertiary amine as hydride donor Tetrahedron Letters 53,4199-4201頁 (共著)
35.	2012/06	論文	Synthesis of Aryl Group-modified DIOP Dioxides (Ar-DIOPOs) and Their Application as Modular Lewis Base Catalysts Org. Biomol. Chem. 10,4562-4570頁 (共著)
36.	2012/06	論文	Trichlorosilyl triflate-mediated enantioselective directed cross-aldol reaction between ketones using a chiral phosphine oxide as an organocatalyst Chemical Communications 48,5524-5526頁 (共著)
37.	2011/08	論文	A Tertiary Amine as A Hydride Donor: Trichlorosilyl Triflate-mediated Conjugate Reduction of Unsaturated Ketones Org. Lett. 13,3968-3971頁 (共著)
38.	2011/07	論文	Enantioselective Double Aldol Reaction Catalyzed by Chiral Phosphine Oxide Chem. Eur. J. 17,7992-7995頁 (共著)
39.	2011/06	論文	Trichlorosilyl Triflate for Enantioselective Direct-type Aldol Reaction with Chiral Phosphine Oxide Tetrahedron Lett. 52,2834-2836頁 (共著)
40.	2011/01	論文	Synthesis of γ-amino alcohols from aldehydes, enamines, and trichlorosilane using Lewis base catalysts Tetrahedron 67,531-539頁 (共著)
41.	2010/11	論文	Enantioselective Conjugate Addition of Boronic Acids to Enones Catalyzed by O-Monoacyltartaric Acids Chem. Commun. 46,7799-7800頁 (共著)
42.	2010/08	論文	Development of Chiral Dinitrones as Modular Lewis Base Catalysts: Asymmetric Allylation of Aldehydes with Allyltrichlorosilanes Tetrahedron: Asymmetry 21,1833-1835頁 (共著)
43.	2010/07	論文	DMAP-catalyzed Cyanation of Aldehydes and Ketones with Ethyl Cyanoformate Tetrahedron Lett. 51,3547-3549頁 (共著)
44.	2010/03	論文	Diastereo- and enantioselective reductive aldol reaction with trichlorosilane using Chiral Lewis bases as organocatalysts Chemistry - An Asian Journal 5,478-481頁 (共著)
45.	2010	論文	「使える！有機合成反応241実践ガイド」 (共著)
46.	2009/08	論文	Novel enantioselective direct aldol-type reaction promoted by a chiral phosphine oxide as an organocatalyst Tetrahedron Letters 50,4602-4605頁 (共著)
47.	2009/07	論文	Asymmetric synthesis of 4H-1,3-oxazines: Enantioselective reductive cyclization of N-acylated β-amino enones with trichlorosilane catalyzed by chiral Lewis bases Chemical Communications,3585-3587頁 (共著)
48.	2009/07	論文	Enantioselective Aldol Reaction of Silyl Ketene Acetals Promoted by a Lewis Base-activated Lewis Acid Catalyst Tetrahedron: Asymmetry 20,1369-1370頁 (共著)
49.	2008/10	論文	Lewis Base-catalyzed Conjugate Reduction and Reductive Aldol Reaction of α,β-Unsaturated Ketones Using Trichlorosilane Chem. Commun.,4309-4311頁 (共著)
50.	2008/06	論文	First Asymmetric Abramov-type Phosphonylation of Aldehydes with Trialkyl Phosphites Catalyzed by Chiral Lewis Bases Tetrahedron 64,6415-6419頁 (共著)
51.	2007/12	論文	C-C Bond formation through addition of C-M to C=O, C=N, and C=N bonds Comprehensive Organometallic Chemistry III 10,403-491頁 (共著)
52.	2007/08	論文	Preparation of phosphinated polymer-incarcerated palladium and its application to C-N and C-C bond-forming reactions Chem. Asian J. 2 (8),983-995頁 (共著)
53.	2006/12	論文	Allylboronation of imines: 1-Phenylhex-5-en-3-amine Organic Syntheses 83,170-176頁 (共著)
54.	2006/12	論文	Development of efficient methods for synthesis of nitrogen-containing compounds using carbamates, acylhydrazines, and ammonia Yakugaku Zasshi 126,1319-1340頁 (単著)
55.	2006/08	論文	Enantioselective Transfer Aminoallylation: Synthesis of Optically Active Homoallylic Primary Amines. J. Am. Chem. Soc. 128,11038-11039頁 (共著)
56.	2006/08	論文	Immobilization of osmium catalysts for asymmetric dihydroxylation of olefins Advanced Synthesis and Catalysis 348,1496-1504頁 (共著)
57.	2006/07	論文	Synthesis of acridone derivatives using polymer-supported palladium and scandium catalysts Journal of Combinatorial Chemistry 8,459-461頁 (共著)
58.	2006/03	論文	Semi-hydrogenation of alkynes using phosphinated polymer incarcerated (PI) palladium catalysts Organic and Biomolecular Chemistry 4,992-995頁 (共著)
59.	2006/02	論文	Practical preparation method of polymer-incarcerated (PI) palladium catalysts using Pd(II) salts Organic Letters 8,375-378頁 (共著)
60.	2006/02	論文	Highly selective preparation of allenic and homopropargylic hydrazides through regiospecific addition of propargyltrichlorosilane and allenyltrichlorosilane to various types of N-acylhydrazones Advanced Synthesis and Catalysis 348,323-329頁 (共著)
61.	2006/01	論文	Highly selective formation of propargyl- and allenyltrichlorosilanes and their regiospecific addition to various types of aldehydes: Preparation of both allenic and homopropargylic alcohols Tetrahedron 62,496-502頁 (共著)
62.	2006	論文	カルバメート、アシルヒドラジン、アンモニアを用いる含窒素化合物の効率的合成法の開発薬学雑誌 126 (12),1319-1340頁 (単著)
63.	2005/12	論文	Cyanation of N-acylhydrazones with trimethylsilyl cyanide promoted by a Brønsted base and a Lewis acid Advanced Synthesis and Catalysis 347,1899-1903頁 (共著)
64.	2005/10	論文	Novel Polymer Incarcerated Palladium with Phosphinated Polymers: Active Catalyst for Suzuki-Miyaura Coupling without External Phosphines Org. Lett. 7,4831-4834頁 (共著)
65.	2005/08	論文	N-Acylhydrazones as Versatile Electrophiles for the Synthesis of Nitrogen-containing Compounds Angew. Chem. Int. Ed. 44,5176-5186頁 (共著)
66.	2005/06	論文	Direct synthesis of unprotected α-amino acids via allylation of hydroxyglycine Canadian Journal of Chemistry 83,937-942頁 (共著)
67.	2005/03	論文	Immobilization of a Platinum Catalyst Using the Polymer Incarcerated (PI) Method and Application to Catalytic Reactions Synlett,813-816頁 (共著)
68.	2005/01	論文	α-aminoallylation of aldehydes in aqueous ammonia Chemical Communications,104-106頁 (共著)
69.	2004/12	論文	Stereospecific, enantioselective allylation of α-hydrazono esters by using allyltrichlorosilanes with BINAP dioxides as neutral-coordinate organocatalysts Angewandte Chemie - International Edition 43,6491-6493頁 (共著)
70.	2004/11	論文	Efficient synthesis of N-acyl-α-amino acids via polymer incarcerated palladium-catalyzed amidocarbonylation Journal of Organometallic Chemistry 689,3806-3809頁 (共著)
71.	2004/08	論文	Neutral Coordinate-organocatalysts in Organic Synthesis. Allylation of Acylhydrazones with Allyltrichlorosilanes Adv. Synth. Cat. 346,1023-1023頁 (共著)
72.	2004/06	論文	α-aminoallylation of aldehydes with ammonia: Stereoselective synthesis of homoallylic primary amines Journal of the American Chemical Society 126,7182-7183頁 (共著)
73.	2004/02	論文	Phosphine Oxides as Efficient Neutral Coordinate-Organocatalysts for Stereoselective Allylation of N-Acylhydrazones Org. Bio. Chem. 2,446-446頁 (共著)
74.	2003/10	論文	Radical-mediated Carbonylation of Alkyl Iodides in Aqueous Media Chem. Lett. 32,898-898頁 (共著)
75.	2003/09	論文	The First Allylation of Imines with Allyltrichlorosilanes Using Neutral Coordinate-Organocatalysts Synlett,1749-1749頁 (共著)
76.	2003/06	論文	Chiral Sulfoxides as Neutral Coordinate-Organocatalysts in Asymmetric Allylation of N-Acylhydrazones Using Allyltrichlorosilanes J. Am. Chem. Soc. 125,6610-6610頁 (共著)
77.	2003/03	論文	Catalytic, Asymmetric Mannich-type Reactions of N-Acylimino Esters: Reactivity, Diastereo- and Enantioselectivity, and Application to Synthesis of N-Acylated Amino Acid Derivatives J. Am. Chem. Soc. 125,2507-2507頁 (共著)
78.	2003/02	論文	Platinum-catalyzed amidocarbonylation Chemistry Letters 32,160-161頁 (共著)
79.	2003/02	論文	Polymer-supported Formamides as Reusable Organocatalysts for Allylation of Aldehydes with Allyltrichlorosilane Chem. Commun. 9,192-192頁 (共著)
80.	2003	論文	有機金属反応剤ハンドブック-3Liから83Biまで (共著)
81.	2002/12	論文	Lewis acid catalyzed ring-opening reactions of sugar-derived semicyclic N,O-acetals Helvetica Chimica Acta 85,3678-3691頁 (共著)
82.	2002/07	論文	Stereoselective synthesis of both syn- and anti-N-tert-alkylamines using highly stereospecific crotylation of ketone-derived acylhydrazones with crotyltrichlorosilanes Journal of Organic Chemistry 67,5359-5364頁 (共著)
83.	2002/06	論文	Rare-earth metal triflates in organic synthesis Chemical Reviews 102,2227-2302頁 (共著)
84.	2002/04	論文	Transition Metal Salts-Catalyzed Aza-Michael Reactions of Enones with Carbamates Organic Letters 4,1319-1322頁 (共著)
85.	2002/01	論文	Palladium-catalyzed direct transformation of carboxylic acids to aldehydes and ketones Chemtracts 15,90-98頁 (共著)
86.	2001/12	論文	Lewis acid-catalyzed ring-opening reactions of semicyclic N,O-acetals possessing an exocyclic nitrogen atom: Mechanistic aspect and application to piperidine alkaloid synthesis Journal of the American Chemical Society 123,12510-12517頁 (共著)
87.	2001/10	論文	Highly stereoselective synthesis of homoallylic amines based on addition of allyltrichlorosilanes to benzoylhydrazones Journal of the American Chemical Society 123,9493-9499頁 (共著)
88.	2001/09	論文	Novel use of ring strain to control regioselectivity: Alkene-directed, palladium-catalyzed allylation [2] Journal of the American Chemical Society 123,9174-9175頁 (共著)
89.	2001/06	論文	A ligand-accelerated chiral Lewis acid catalyst in asymmetric Michael addition of thiols to α,β-unsaturated carbonyls Synlett,983-985頁 (共著)
90.	2001/02	論文	Lewis Acid-Catalyzed Ring-Opening Reactions of Semicyclic N,O-Acetals Organic Letters 3,477-480頁 (共著)
91.	2001/01	論文	Ring-opening allylation of semicyclic N,O-acetals catalyzed by a Lewis acid Synlett,1225-1228頁 (共著)
92.	1998/06	論文	Chiral dienolate-based remote asymmetric induction: The asymmetric α- oxylation/Pd(0)-catalyzed allylic substitution sequence leading to γ-chiral α,β-unsaturated acid derivatives Tetrahedron Letters 39,4351-4354頁 (共著)
93.	1997/01	論文	Asymmetric catalytic protonation of silyl enol ethers with chiral palladium complexes Angewandte Chemie - International Edition in English 36,2366-2368頁 (共著)
94.	1996/10	論文	Regiochemical control in the Pd(II)-catalyzed Claisen rearrangement via in situ enol ether exchange Tetrahedron Letters 37,7991-7994頁 (共著)
95.	1993/12	論文	A novel and stereodefined synthesis of (E)-β- ethoxycarbonylvinylsilanes: Regio- and stereo-controlled hydroethoxycarbonylation of silylacetylenes by palladium(II) catalysis Journal of the Chemical Society, Perkin Transactions 1,1031-1037頁 (共著)
96.	1992/12	論文	The highly regioselective carbonylation of vinylsilanes Journal of Organic Chemistry 57,4189-4194頁 (共著)