Faculty Information - Sugiura Masaharu

Sugiura Masaharu

Department / Course FACULTY OF PHARMACEUTICAL SCIENCES Department of Pharmaceutical Sciences

Job

Book and thesis
1.	2024/01	Papers	Conversion of raltegravir carrying a 1,3,4-oxadiazole ring to a hydrolysis product upon pH changes decreases its antiviral activity. PNAS nexus 3 (1),pp.pgad446 (Co-authored)
2.	2023/07	Papers	Lithium Binaphtholate-Catalyzed Asymmetric Michael Reaction of Acrylamides. Chemical & pharmaceutical bulletin 71 (10),pp.792-797 (Co-authored)
3.	2023/12	Papers	Recruitment of hexahydroquinoline as anticancer scaffold targeting inhibition of wild and mutants EGFR (EGFRWT, EGFRT790M, and EGFRL858R). Journal of enzyme inhibition and medicinal chemistry 38 (1),pp.2241674 (Co-authored)
4.	2023/01	Papers	Synthesis of Selenoesters via Aldol Condensation and/or Conjugate Reduction and Their Antiviral Activities. ACS omega 8 (1),pp.1369-1374 (Co-authored)
5.	2022/10	Papers	Synthesis, crystallographic, DNA binding, and molecular docking/dynamic studies of a privileged chalcone-sulfonamide hybrid scaffold as a promising anticancer agent. Journal of biomolecular structure & dynamics,pp.1-15 (Co-authored)
6.	2021/05	Papers	Aromatic-Turmerone Analogs Protect Dopaminergic Neurons in Midbrain Slice Cultures through Their Neuroprotective Activities. Cells 10 (5) (Co-authored)
7.	2020/10	Books	"Catalysis by Silicon Species (Chapter 11)" In "Catalysis with Earth-abundant Elements",pp.309-333 (Co-authored)
8.	2020/09	Papers	Synthesis of conjugated multiunsaturated thioesters via one-pot TiCl4-promoted aldol condensation Tetrahedron Letters 61 (36),pp.152280 (Co-authored)
9.	2020/05	Papers	O-Monoacyltartaric Acid/(Thio)urea Cooperative Organocatalysis for Enantioselective Conjugate Addition of Boronic Acid. Organic letters 22 (10),pp.3780-3784 (Co-authored)
10.	2019/08	Papers	Lewis Base-Catalyzed Enantioselective Conjugate Reduction of β,β-Disubstituted α,β-Unsaturated Ketones with Trichlorosilane: E/Z-Isomerization, Regioselectivity, and Synthetic Applications. [Highlighted in Organic Chemistry Portal; Featured in Org. Chem. Highlights: Alkylated Stereogenic Centers] The Journal of Organic Chemistry 84 (18),pp.11458-11473 (Co-authored)
11.	2019/06	Papers	Selective Monoacylation of Diols and Asymmetric Desymmetrization of Dialkyl meso-Tartrates Using 2-Pyridyl Esters as Acylating Agents and Metal Carboxylates as Catalysts. The Journal of Organic Chemistry 84 (14),pp.9313-9321 (Co-authored)
12.	2018/11	Papers	Catalytic Enantioselective Aldol Reactions of Unprotected Carboxylic Acids under Phosphine Oxide Catalysis Angewandte Chemie - International Edition 57,pp.15877-15881 (Co-authored)
13.	2018/06	Papers	Activation of Boron Compounds by O-Monoacyltartaric Acid Catalysts,pp.596-603 (Sole-authored)
14.	2017/10	Papers	Stereoselective Synthesis of Nitrogen-Containing Compounds from Enamines. The Journal of organic chemistry 82 (20),pp.10968-10979 (Co-authored)
15.	2017/07	Papers	Sequential Catalysis of Phosphine Oxide for Stereoselective Synthesis of Stereopentads. Organic letters 19 (13),pp.3672-3675 (Co-authored)
16.	2017/01	Papers	Enantioselective chlorinative aldol reaction of α-substituted acroleins catalyzed by chiral phosphine oxides Tetrahedron Asymmetry 28 (2),pp.282-287 (Co-authored)
17.	2017	Papers	Asymmetric Aldol/Vinylogous Aldol/Cyclization Reaction Using Phosphine Oxide Catalysts. Chemical & pharmaceutical bulletin 65 (10),pp.989-993 (Co-authored)
18.	2016/02	Papers	Concise Asymmetric Construction of C<inf>2</inf>-symmetric 1,9-Diarylnonanoids Using a Hypervalent Silicon Complex: Total Synthesis of (-)-Ericanone Chemistry - An Asian Journal 11,pp.376-379 (Co-authored)
19.	2016/02	Papers	Stereoselective Synthesis of Highly Functionalized 2,3-Dihydro-4-pyranones Using Phosphine Oxide as Catalyst. Chem. Pharm. Bull. 64 (2),pp.189-192 (Co-authored)
20.	2015/08	Papers	One-Pot Synthesis of β,β-Disubstituted α,β-Unsaturated Carbonyl Compounds. J. Org. Chem. 80,pp.8830-8835 (Co-authored)
21.	2015/08	Papers	Conjugate Addition of Diboron Catalyzed by O-Monoacyltartaric Acids. Synthesis 47,pp.2265-2269 (Co-authored)
22.	2014/10	Papers	O-Monoacyltartaric Acid-Catalyzed Enantioselective Conjugate Addition of a Boronic Acid to Dienones: Application to the Synthesis of Optically Active Cyclopentenones. Org. Lett. 16,pp.5172-5175 (Co-authored)
23.	2014/09	Papers	Phosphine Oxide-Catalyzed Enantioselective Intramolecular Aldol Reaction via Regioselective Enolization of Unsymmetrical Diketones with Tetrachlorosilane. Org. Lett. 16,pp.4802-4805 (Co-authored)
24.	2014/07	Papers	Imino ene-type reaction of enamines with N-sulfonylimines and application to diastereoselective synthesis of N-sulfonyl-1,3-diamines Tetrahedron Letters 55,pp.4082-4085 (Co-authored)
25.	2014/07	Papers	A Hydrogen Bond Rationale for the Enantioselective β-Alkenylboration of Enones Catalyzed by O-Monoacyltartaric Acids. J. Org. Chem. 79,pp.6754-6758 (Co-authored)
26.	2014/03	Papers	Diastereoselective Synthesis of 1,3-Diamines by a Domino Reaction of Imines, Enamines, and Trichlorosilane. Tetrahedron Lett. 55,pp.1924-1926 (Co-authored)
27.	2014/01	Papers	Enantioselective Double Aldol Reactions Involving the Sequential Activation of Silicon Tetrachloride by Chiral Phosphine Oxides. Synlett 25,pp.631-640 (Co-authored)
28.	2013/12	Papers	Atropisomeric chiral dienes in asymmetric catalysis: C<inf>2</inf>- symmetric (Z,Z)-2,3-Bis[1-(diphenylphosphinyl)ethylidene]tetralin as a highly active lewis base organocatalyst Angewandte Chemie - International Edition 52,pp.13798-13802 (Co-authored)
29.	2013/11	Papers	Enantioselective Morita–Baylis–Hillman Reaction Catalyzed by a Chiral Phosphine oxide. Tetrahedron Lett. 54,pp.6430-6433 (Co-authored)
30.	2013/08	Papers	Enantioselective aldol reactions catalyzed by chiral phosphine oxides Chemical Record 13,pp.362-370 (Co-authored)
31.	2013/04	Papers	Facile Synthesis of Chiral 1,2-Chlorohydrins via the Ring-opening of meso-Epoxides Catalyzed by Chiral Phosphine Oxides Tetrahedron 69,pp.3075-3081 (Co-authored)
32.	2013/03	Papers	Stereoselective Synthesis of Multiple Stereocenters by Using a Double Aldol Reaction Angew. Chem. Int. Ed. 52,pp.3461-3464 (Co-authored)
33.	2012/09	Papers	6.8 Allylations of C-O and C-N Double Bonds and Related Reactions Comprehensive Chirality 6,pp.214-233 (Co-authored)
34.	2012/08	Papers	Enantioselective reductive aldol reaction using tertiary amine as hydride donor Tetrahedron Letters 53,pp.4199-4201 (Co-authored)
35.	2012/06	Papers	Synthesis of Aryl Group-modified DIOP Dioxides (Ar-DIOPOs) and Their Application as Modular Lewis Base Catalysts Org. Biomol. Chem. 10,pp.4562-4570 (Co-authored)
36.	2012/06	Papers	Trichlorosilyl triflate-mediated enantioselective directed cross-aldol reaction between ketones using a chiral phosphine oxide as an organocatalyst Chemical Communications 48,pp.5524-5526 (Co-authored)
37.	2011/08	Papers	A Tertiary Amine as A Hydride Donor: Trichlorosilyl Triflate-mediated Conjugate Reduction of Unsaturated Ketones Org. Lett. 13,pp.3968-3971 (Co-authored)
38.	2011/07	Papers	Enantioselective Double Aldol Reaction Catalyzed by Chiral Phosphine Oxide Chem. Eur. J. 17,pp.7992-7995 (Co-authored)
39.	2011/06	Papers	Trichlorosilyl Triflate for Enantioselective Direct-type Aldol Reaction with Chiral Phosphine Oxide Tetrahedron Lett. 52,pp.2834-2836 (Co-authored)
40.	2011/01	Papers	Synthesis of γ-amino alcohols from aldehydes, enamines, and trichlorosilane using Lewis base catalysts Tetrahedron 67,pp.531-539 (Co-authored)
41.	2010/11	Papers	Enantioselective Conjugate Addition of Boronic Acids to Enones Catalyzed by O-Monoacyltartaric Acids Chem. Commun. 46,pp.7799-7800 (Co-authored)
42.	2010/08	Papers	Development of Chiral Dinitrones as Modular Lewis Base Catalysts: Asymmetric Allylation of Aldehydes with Allyltrichlorosilanes Tetrahedron: Asymmetry 21,pp.1833-1835 (Co-authored)
43.	2010/07	Papers	DMAP-catalyzed Cyanation of Aldehydes and Ketones with Ethyl Cyanoformate Tetrahedron Lett. 51,pp.3547-3549 (Co-authored)
44.	2010/03	Papers	Diastereo- and enantioselective reductive aldol reaction with trichlorosilane using Chiral Lewis bases as organocatalysts Chemistry - An Asian Journal 5,pp.478-481 (Co-authored)
45.	2009/08	Papers	Novel enantioselective direct aldol-type reaction promoted by a chiral phosphine oxide as an organocatalyst Tetrahedron Letters 50,pp.4602-4605 (Co-authored)
46.	2009/07	Papers	Asymmetric synthesis of 4H-1,3-oxazines: Enantioselective reductive cyclization of N-acylated β-amino enones with trichlorosilane catalyzed by chiral Lewis bases Chemical Communications,pp.3585-3587 (Co-authored)
47.	2009/07	Papers	Enantioselective Aldol Reaction of Silyl Ketene Acetals Promoted by a Lewis Base-activated Lewis Acid Catalyst Tetrahedron: Asymmetry 20,pp.1369-1370 (Co-authored)
48.	2008/10	Papers	Lewis Base-catalyzed Conjugate Reduction and Reductive Aldol Reaction of α,β-Unsaturated Ketones Using Trichlorosilane Chem. Commun.,pp.4309-4311 (Co-authored)
49.	2008/06	Papers	First Asymmetric Abramov-type Phosphonylation of Aldehydes with Trialkyl Phosphites Catalyzed by Chiral Lewis Bases Tetrahedron 64,pp.6415-6419 (Co-authored)
50.	2007/12	Papers	C-C Bond formation through addition of C-M to C=O, C=N, and C=N bonds Comprehensive Organometallic Chemistry III 10,pp.403-491 (Co-authored)
51.	2007/08	Papers	Preparation of phosphinated polymer-incarcerated palladium and its application to C-N and C-C bond-forming reactions Chem. Asian J. 2 (8),pp.983-995 (Co-authored)
52.	2006/12	Papers	Allylboronation of imines: 1-Phenylhex-5-en-3-amine Organic Syntheses 83,pp.170-176 (Co-authored)
53.	2006/08	Papers	Enantioselective Transfer Aminoallylation: Synthesis of Optically Active Homoallylic Primary Amines. J. Am. Chem. Soc. 128,pp.11038-11039 (Co-authored)
54.	2006/08	Papers	Immobilization of osmium catalysts for asymmetric dihydroxylation of olefins Advanced Synthesis and Catalysis 348,pp.1496-1504 (Co-authored)
55.	2006/07	Papers	Synthesis of acridone derivatives using polymer-supported palladium and scandium catalysts Journal of Combinatorial Chemistry 8,pp.459-461 (Co-authored)
56.	2006/03	Papers	Semi-hydrogenation of alkynes using phosphinated polymer incarcerated (PI) palladium catalysts Organic and Biomolecular Chemistry 4,pp.992-995 (Co-authored)
57.	2006/02	Papers	Practical preparation method of polymer-incarcerated (PI) palladium catalysts using Pd(II) salts Organic Letters 8,pp.375-378 (Co-authored)
58.	2006/02	Papers	Highly selective preparation of allenic and homopropargylic hydrazides through regiospecific addition of propargyltrichlorosilane and allenyltrichlorosilane to various types of N-acylhydrazones Advanced Synthesis and Catalysis 348,pp.323-329 (Co-authored)
59.	2006/01	Papers	Highly selective formation of propargyl- and allenyltrichlorosilanes and their regiospecific addition to various types of aldehydes: Preparation of both allenic and homopropargylic alcohols Tetrahedron 62,pp.496-502 (Co-authored)
60.	2005/12	Papers	Cyanation of N-acylhydrazones with trimethylsilyl cyanide promoted by a Brønsted base and a Lewis acid Advanced Synthesis and Catalysis 347,pp.1899-1903 (Co-authored)
61.	2005/10	Papers	Novel Polymer Incarcerated Palladium with Phosphinated Polymers: Active Catalyst for Suzuki-Miyaura Coupling without External Phosphines Org. Lett. 7,pp.4831-4834 (Co-authored)
62.	2005/08	Papers	N-Acylhydrazones as Versatile Electrophiles for the Synthesis of Nitrogen-containing Compounds Angew. Chem. Int. Ed. 44,pp.5176-5186 (Co-authored)
63.	2005/06	Papers	Direct synthesis of unprotected α-amino acids via allylation of hydroxyglycine Canadian Journal of Chemistry 83,pp.937-942 (Co-authored)
64.	2005/03	Papers	Immobilization of a Platinum Catalyst Using the Polymer Incarcerated (PI) Method and Application to Catalytic Reactions Synlett,pp.813-816 (Co-authored)
65.	2005/01	Papers	α-aminoallylation of aldehydes in aqueous ammonia Chemical Communications,pp.104-106 (Co-authored)
66.	2004/12	Papers	Stereospecific, enantioselective allylation of α-hydrazono esters by using allyltrichlorosilanes with BINAP dioxides as neutral-coordinate organocatalysts Angewandte Chemie - International Edition 43,pp.6491-6493 (Co-authored)
67.	2004/11	Papers	Efficient synthesis of N-acyl-α-amino acids via polymer incarcerated palladium-catalyzed amidocarbonylation Journal of Organometallic Chemistry 689,pp.3806-3809 (Co-authored)
68.	2004/08	Papers	Neutral Coordinate-organocatalysts in Organic Synthesis. Allylation of Acylhydrazones with Allyltrichlorosilanes Adv. Synth. Cat. 346,pp.1023-1023 (Co-authored)
69.	2004/06	Papers	α-aminoallylation of aldehydes with ammonia: Stereoselective synthesis of homoallylic primary amines Journal of the American Chemical Society 126,pp.7182-7183 (Co-authored)
70.	2004/02	Papers	Phosphine Oxides as Efficient Neutral Coordinate-Organocatalysts for Stereoselective Allylation of N-Acylhydrazones Org. Bio. Chem. 2,pp.446-446 (Co-authored)
71.	2003/10	Papers	Radical-mediated Carbonylation of Alkyl Iodides in Aqueous Media Chem. Lett. 32,pp.898-898 (Co-authored)
72.	2003/09	Papers	The First Allylation of Imines with Allyltrichlorosilanes Using Neutral Coordinate-Organocatalysts Synlett,pp.1749-1749 (Co-authored)
73.	2003/06	Papers	Chiral Sulfoxides as Neutral Coordinate-Organocatalysts in Asymmetric Allylation of N-Acylhydrazones Using Allyltrichlorosilanes J. Am. Chem. Soc. 125,pp.6610-6610 (Co-authored)
74.	2003/03	Papers	Catalytic, Asymmetric Mannich-type Reactions of N-Acylimino Esters: Reactivity, Diastereo- and Enantioselectivity, and Application to Synthesis of N-Acylated Amino Acid Derivatives J. Am. Chem. Soc. 125,pp.2507-2507 (Co-authored)
75.	2003/02	Papers	Platinum-catalyzed amidocarbonylation Chemistry Letters 32,pp.160-161 (Co-authored)
76.	2003/02	Papers	Polymer-supported Formamides as Reusable Organocatalysts for Allylation of Aldehydes with Allyltrichlorosilane Chem. Commun. 9,pp.192-192 (Co-authored)
77.	2002/12	Papers	Lewis acid catalyzed ring-opening reactions of sugar-derived semicyclic N,O-acetals Helvetica Chimica Acta 85,pp.3678-3691 (Co-authored)
78.	2002/07	Papers	Stereoselective synthesis of both syn- and anti-N-tert-alkylamines using highly stereospecific crotylation of ketone-derived acylhydrazones with crotyltrichlorosilanes Journal of Organic Chemistry 67,pp.5359-5364 (Co-authored)
79.	2002/06	Papers	Rare-earth metal triflates in organic synthesis Chemical Reviews 102,pp.2227-2302 (Co-authored)
80.	2002/04	Papers	Transition Metal Salts-Catalyzed Aza-Michael Reactions of Enones with Carbamates Organic Letters 4,pp.1319-1322 (Co-authored)
81.	2002/01	Papers	Palladium-catalyzed direct transformation of carboxylic acids to aldehydes and ketones Chemtracts 15,pp.90-98 (Co-authored)
82.	2001/12	Papers	Lewis acid-catalyzed ring-opening reactions of semicyclic N,O-acetals possessing an exocyclic nitrogen atom: Mechanistic aspect and application to piperidine alkaloid synthesis Journal of the American Chemical Society 123,pp.12510-12517 (Co-authored)
83.	2001/10	Papers	Highly stereoselective synthesis of homoallylic amines based on addition of allyltrichlorosilanes to benzoylhydrazones Journal of the American Chemical Society 123,pp.9493-9499 (Co-authored)
84.	2001/09	Papers	Novel use of ring strain to control regioselectivity: Alkene-directed, palladium-catalyzed allylation [2] Journal of the American Chemical Society 123,pp.9174-9175 (Co-authored)
85.	2001/06	Papers	A ligand-accelerated chiral Lewis acid catalyst in asymmetric Michael addition of thiols to α,β-unsaturated carbonyls Synlett,pp.983-985 (Co-authored)
86.	2001/02	Papers	Lewis Acid-Catalyzed Ring-Opening Reactions of Semicyclic N,O-Acetals Organic Letters 3,pp.477-480 (Co-authored)
87.	2001/01	Papers	Ring-opening allylation of semicyclic N,O-acetals catalyzed by a Lewis acid Synlett,pp.1225-1228 (Co-authored)
88.	1998/06	Papers	Chiral dienolate-based remote asymmetric induction: The asymmetric α- oxylation/Pd(0)-catalyzed allylic substitution sequence leading to γ-chiral α,β-unsaturated acid derivatives Tetrahedron Letters 39,pp.4351-4354 (Co-authored)
89.	1997/01	Papers	Asymmetric catalytic protonation of silyl enol ethers with chiral palladium complexes Angewandte Chemie - International Edition in English 36,pp.2366-2368 (Co-authored)
90.	1996/10	Papers	Regiochemical control in the Pd(II)-catalyzed Claisen rearrangement via in situ enol ether exchange Tetrahedron Letters 37,pp.7991-7994 (Co-authored)
91.	1993/12	Papers	A novel and stereodefined synthesis of (E)-β- ethoxycarbonylvinylsilanes: Regio- and stereo-controlled hydroethoxycarbonylation of silylacetylenes by palladium(II) catalysis Journal of the Chemical Society, Perkin Transactions 1,pp.1031-1037 (Co-authored)
92.	1992/12	Papers	The highly regioselective carbonylation of vinylsilanes Journal of Organic Chemistry 57,pp.4189-4194 (Co-authored)