Faculty Information - Kadowaki Daisuke

Kadowaki Daisuke

Department / Course FACULTY OF PHARMACEUTICAL SCIENCES Department of Pharmaceutical Sciences

Job

Book and thesis
1.	2026/08	Papers	5-hydroxy-1-methylhydantoin (NZ-419), an endogenous antioxidant, attenuates mycotoxin-induced oxidative stress in human kidney proximal tubular epithelial cells. Clinical and experimental nephrology (Co-authored)
2.	2026/07	Papers	Pharmaceutical optimization of chitosan tablets is associated with reduced circulating bile acids and fibrosis-related molecular signatures in non-alcoholic steatohepatitis rats. Carbohydrate polymers 383,pp.125333 (Co-authored)
3.	2026/07	Papers	Trends in sodium-glucose transport protein 2 inhibitor prescriptions: application of the ATC/DDD system to NDB open data. Diabetology international 17 (3),pp.40 (Co-authored)
4.	2026/04	Papers	Lactulose, a Disaccharide Prebiotic, Improves the Gut-Kidney Axis via Enhancement of Akkermansia Muciniphila Production. Kidney360 7 (4),pp.754-766 (Co-authored)
5.	2026/02/27	Papers	Prescription Patterns of Calcimimetics and CKD‒MBD‒related Drugs：Analysis Using National Database of Health Insurance Claims and Specific Health Checkups of Japan,pp.1-8 (Co-authored)
6.	2025/12/09	Papers	TrendsinOralAntidiabeticDrugPrescriptionsinJapan(2014 2023):ALongitudinalAnalysisUsing NDBOpenData,pp.28-34 (Co-authored)
7.	2025/01/23	Papers	A Survey of the Actual State of Medication Adherence and Physical Condition Management Among Outpatients with Heart Failure Before and After the Introduction of the Heart Failure Seal,pp.307-317 (Co-authored)
8.	2022/03	Papers	In Vitro and In Vivo Assessment of Atemoya Fruit (Annona atemoya) for Food-Drug Interactions. European journal of drug metabolism and pharmacokinetics 47 (2),pp.177-185 (Co-authored)
9.	2022	Papers	The Effects of Sacran, a Sulfated Polysaccharide, on Gut Microbiota Using Chronic Kidney Disease Model Rats. Biological & pharmaceutical bulletin 45 (5),pp.576-582 (Co-authored)
10.	2022	Papers	New Insight Concerning Therapeutic Drug Monitoring-The Importance of the Concept of Psychonephrology. Biological & pharmaceutical bulletin 45 (7),pp.834-842 (Co-authored)
11.	2020/10	Papers	Effect of Cinacalcet on the Redox Status of Albumin in Secondary Hyperparathyroidism Patients Receiving Hemodialysis. Biol Pharm Bull. 43 (10),pp.1583-1590 (Co-authored)
12.	2021/12	Papers	Evaluation of renal function using cystatin C-based estimated glomerular filtration rate in patients with urothelial carcinoma treated with gemcitabine and cisplatin chemotherapy. Journal of clinical pharmacy and therapeutics 46 (6),pp.1622-1628 (Co-authored)
13.	2020/06	Papers	In vivo evaluation of drug dialyzability in a rat model of hemodialysis. PloS one 15 (6),pp.e0233925 (Co-authored)
14.	2021/06	Papers	Correction to: Awareness and current implementation of drug dosage adjustment by pharmacists in patients with chronic kidney disease in Japan: a web-based survey. BMC health services research 21 (1),pp.617 (Co-authored)
15.	2021/03	Papers	Sacran, a sulfated polysaccharide, suppresses the absorption of lipids and modulates the intestinal flora in non-alcoholic steatohepatitis model rats. Life sciences 268,pp.118991 (Co-authored)
16.	2020/12	Papers	Effects of surface-deacetylated chitin nanofibers on non-alcoholic steatohepatitis model rats and their gut microbiota. Int J Biol Macromol. 164,pp.659-666 (Co-authored)
17.	2021	Papers	Comparison between the Effects of Loxoprofen and Acetaminophen on Postoperative Pain Following Radical Prostatectomy: A Propensity Score Matching Analysis. Biological & pharmaceutical bulletin 44 (10),pp.1427-1432 (Co-authored)
18.	2020/04	Papers	Comparative Study of Constipation Exacerbation by Potassium Binders Using a Loperamide-Induced Constipation Model. International journal of molecular sciences 21 (7) (Co-authored)
19.	2020/08	Papers	Investigation of methods for more accurate estimation of kidney function in people with high muscle mass . Clin Nephrol. 96 (2),pp.86-96 (Co-authored)
20.	2020/03	Papers	Processing grapefruit juice with γ-cyclodextrin attenuates its inhibitory effect on cytochrome P450 3A activity. The Journal of pharmacy and pharmacology 72 (3),pp.356-363 (Co-authored)
21.	2020	Papers	Toxicological Property of Acetaminophen: The Dark Side of a Safe Antipyretic/Analgesic Drug? Biological & pharmaceutical bulletin 43 (2),pp.195-206 (Co-authored)
22.	2019/03	Papers	Effects of lactulose on renal function and gut microbiota in adenine-induced chronic kidney disease rats. Clinical and experimental nephrology (Co-authored)
23.	2019	Papers	Knowledge and awareness of nonpharmacist salespersons regarding over-the-counter drug use in patients with chronic kidney disease in Japan. PloS one 14 (3),pp.e0213763 (Co-authored)
24.	2019/08	Papers	Edoxaban Exerts Antioxidant Effects Through FXa Inhibition and Direct Radical-Scavenging Activity. International journal of molecular sciences 20 (17) (Co-authored)
25.	2019/08	Papers	Coefficient of Determination between Estimated and Measured Renal Function in Japanese Patients with Sarcopenia May Be Improved by Adjusting for Muscle Mass and Sex: A Prospective Study. Biological & pharmaceutical bulletin 42 (8),pp.1350-1357 (Co-authored)
26.	2018/06	Papers	Benzbromarone Attenuates Oxidative Stress in Angiotensin II- and Salt-Induced Hypertensive Model Rats. Oxid Med Cell Longev. 7635274 (Co-authored)
27.	2018/09	Papers	Simple Formula for Predicting Drug Removal Rates During Hemodialysis. Ther Apher Dial. 22 (5),pp.485-493 (Co-authored)
28.	2018/02	Papers	Ethyl pyruvate attenuates acetaminophen-induced liver injury and prevents cellular injury induced byN-acetyl-p-benzoquinone imine. Heliyon 4 (2),pp.e00521 (Co-authored)
29.	2018/02	Papers	Guidelines for treatment of renal injury during cancer chemotherapy 2016. Clinical and experimental nephrology 22 (1),pp.210-244 (Co-authored)
30.	2017/07	Papers	A Comparison of the Phosphorus Content in Prescription Medications for Hemodialysis Patients in Japan. Yakugaku Zasshi 137 (7),pp.903-908 (Co-authored)
31.	2016/02	Papers	Combination therapy with renin-angiotensin-aldosterone system inhibitor telmisartan and serine protease inhibitor camostat mesilate provides further renoprotection in a rat chronic kidney disease model. Journal of pharmacological sciences 130 (2),pp.110-6 (Co-authored)
32.	2016	Papers	Effect of a Ferric Citrate Formulation, a Phosphate Binder, on Oxidative Stress in Chronic Kidney Diseases-Mineral and Bone Disorder Patients Receiving Hemodialysis: A Pilot Study. Biological & pharmaceutical bulletin 39 (6),pp.1000-6 (Co-authored)
33.	2016	Papers	The Effect of Yokukansan, a Traditional Herbal Preparation Used for the Behavioral and Psychological Symptoms of Dementia, on the Drug-Metabolizing Enzyme Activities in Healthy Male Volunteers. Biological & pharmaceutical bulletin 39 (9),pp.1468-74 (Co-authored)
34.	2015/12	Papers	Olmesartan protects endothelial cells against oxidative stress-mediated cellular injury. Clinical and experimental nephrology 19 (6),pp.1007-14 (Co-authored)
35.	2015/02	Papers	p-Cresyl sulfate, a uremic toxin, causes vascular endothelial and smooth muscle cell damages by inducing oxidative stress. Pharmacology research & perspectives 3 (1),pp.e00092 (Co-authored)
36.	2015	Papers	Direct radical scavenging activity of benzbromarone provides beneficial antioxidant properties for hyperuricemia treatment. Biological & pharmaceutical bulletin 38 (3),pp.487-92 (Co-authored)
37.	2015	Papers	The serine protease inhibitor camostat mesilate attenuates the progression of chronic kidney disease through its antioxidant effects. Nephron 129 (3),pp.223-32 (Co-authored)
38.	2014/12	Papers	Awareness and current implementation of drug dosage adjustment by pharmacists in patients with chronic kidney disease in Japan: a web-based survey. BMC health services research 14,pp.615 (Co-authored)
39.	2014/10	Papers	Possible false-negative results on therapeutic drug monitoring of phenytoin using a particle enhanced turbidimetric inhibition immunoassay in a patient with a high level of IgM. Therapeutic drug monitoring 36 (5),pp.553-5 (Co-authored)
40.	2014	Papers	Cys34-cysteinylated human serum albumin is a sensitive plasma marker in oxidative stress-related chronic diseases. PloS one 9 (1),pp.e85216 (Co-authored)
41.	2014	Papers	Differential effects of methoxy group on the interaction of curcuminoids with two major ligand binding sites of human serum albumin. PloS one 9 (2),pp.e87919 (Co-authored)
42.	2013/06	Papers	Comparative effects of respiratory stimulants on hypoxic neuronal cell injury in SH-SY5Y cells and in hippocampal slice cultures from rat pups. Pediatrics international : official journal of the Japan Pediatric Society 55 (3),pp.320-7 (Co-authored)
43.	2013/04	Papers	p-Cresyl sulfate causes renal tubular cell damage by inducing oxidative stress by activation of NADPH oxidase. Kidney international 83 (4),pp.582-92 (Co-authored)
44.	2013/03	Papers	Phosphoenolpyruvate, a glycolytic intermediate, as a cytoprotectant and antioxidant in ex-vivo cold-preserved mouse liver: a potential application for organ preservation. The Journal of pharmacy and pharmacology 65 (3),pp.390-401 (Co-authored)
45.	2013	Papers	Comparative Effects of Phosphoenolpyruvate, a Glycolytic Intermediate, as an Organ Preservation Agent with Glucose and N-Acetylcysteine against Organ Damage during Cold Storage of Mouse Liver and Kidney. ISRN pharmacology 2013,pp.375825 (Co-authored)
46.	2012/12	Papers	Effect of acetaminophen on the progression of renal damage in adenine induced renal failure model rats. Life sciences 91 (25-26),pp.1304-8 (Co-authored)
47.	2012/11	Papers	A uremic toxin, 3-carboxy-4-methyl-5-propyl-2-furanpropionate induces cell damage to proximal tubular cells via the generation of a radical intermediate. Biochemical pharmacology 84 (9),pp.1207-14 (Co-authored)
48.	2012/07	Papers	Interaction between two sulfate-conjugated uremic toxins, p-cresyl sulfate and indoxyl sulfate, during binding with human serum albumin. Drug metabolism and disposition: the biological fate of chemicals 40 (7),pp.1423-8 (Co-authored)
49.	2012	Papers	Appropriate drug dosing in patients receiving peritoneal dialysis. Contributions to nephrology 177,pp.30-7 (Co-authored)
50.	2012	Papers	Phosphoenolpyruvic acid, an intermediary metabolite of glycolysis, as a potential cytoprotectant and anti-oxidant in HeLa cells. Biological & pharmaceutical bulletin 35 (4),pp.606-11 (Co-authored)
51.	2011/09	Papers	Quantitative analysis of cysteine-34 on the anitioxidative properties of human serum albumin in hemodialysis patients. Journal of pharmaceutical sciences 100 (9),pp.3968-76 (Co-authored)
52.	2011/08	Papers	Loss of functional albumin triggers acceleration of transthyretin amyloid fibril formation in familial amyloidotic polyneuropathy. Laboratory investigation; a journal of technical methods and pathology 91 (8),pp.1219-28 (Co-authored)
53.	2011/08	Papers	Organic anion transporters play an important role in the uptake of p-cresyl sulfate, a uremic toxin, in the kidney. Nephrology, dialysis, transplantation 26 (8),pp.2498-502 (Co-authored)
54.	2011/06	Papers	Removal of doripenem during hemodialysis and the optimum dosing regimen for patients undergoing hemodialysis. Therapeutic apheresis and dialysis 15 (3),pp.327-33 (Co-authored)
55.	2011/04	Papers	Fluid resuscitation with hemoglobin vesicles prevents Escherichia coli growth via complement activation in a hemorrhagic shock rat model. The Journal of pharmacology and experimental therapeutics 337 (1),pp.201-8 (Co-authored)
56.	2011/04	Papers	Vitamin D receptor activator reduces oxidative stress in hemodialysis patients with secondary hyperparathyroidism. Therapeutic apheresis and dialysis 15 (2),pp.161-8 (Co-authored)
57.	2011/03	Papers	Repeated injection of high doses of hemoglobin-encapsulated liposomes (hemoglobin vesicles) induces accelerated blood clearance in a hemorrhagic shock rat model. Drug metabolism and disposition: the biological fate of chemicals 39 (3),pp.484-9 (Co-authored)
58.	2011	Papers	Toxicodynamic evaluation of a cisplatin-chondroitin sulfate complex using a perfused kidney and human proximal tubular cells. Renal failure 33 (6),pp.609-14 (Co-authored)
59.	2010	Papers	Construction of an expression system for human alpha(1)-acid glycoprotein in E. coli: The roles of oligosaccharide moieties in structural and functional properties. Drug metabolism and pharmacokinetics 25 (2),pp.200-7 (Co-authored)
60.	2010	Papers	Receptor-mediated uptake of human alpha1-acid glycoprotein into liver parenchymal cells in mice. Drug metabolism and pharmacokinetics 25 (1),pp.101-7 (Co-authored)
61.	2009/12	Papers	Evaluation for antioxidant and renoprotective activity of olmesartan using nephrectomy rats. Biological & pharmaceutical bulletin 32 (12),pp.2041-5 (Co-authored)
62.	2009/11	Papers	A site-directed mutagenesis study of drug-binding selectivity in genetic variants of human alpha(1)-acid glycoprotein. Journal of pharmaceutical sciences 98 (11),pp.4316-26 (Co-authored)
63.	2009/11	Papers	Hemoglobin vesicles, polyethylene glycol (PEG)ylated liposomes developed as a red blood cell substitute, do not induce the accelerated blood clearance phenomenon in mice. Drug metabolism and disposition: the biological fate of chemicals 37 (11),pp.2197-203 (Co-authored)
64.	2009/01	Papers	Antioxidant effects of a dietary supplement: reduction of indices of oxidative stress in normal subjects by water-soluble chitosan. Food and chemical toxicology 47 (1),pp.104-9 (Co-authored)
65.	2007/07	Papers	Alpha1-acid glycoprotein suppresses rat acute inflammatory paw edema through the inhibition of neutrophils activation and prostaglandin E2 generation. Biological & pharmaceutical bulletin 30 (7),pp.1226-30 (Co-authored)
66.	2007/05	Papers	Effect of olmesartan on oxidative stress in hemodialysis patients. Hypertension research : official journal of the Japanese Society of Hypertension 30 (5),pp.395-402 (Co-authored)