教員情報 - 原武　衛

ハラタケ　マモル Haratake Mamoru
原武　衛

所属薬学部薬学科

職種教授

著書・論文歴
1.	2022/12	論文	Bioavailability of selenium from selenotrisulfides in primary cultured neuronal cells Metallomics Research 2 (3),reg-1-reg-11頁 (共著)
2.	2021/04	論文	Preparation of enzymatically highly active pegylated-D-amino acid oxidase and its application to antitumor therapy Current Drug Delivery 18,1121-1129頁 (共著)
3.	2021/05	論文	Acid-responsive HPMA copolymer-bradykinin conjugate enhances tumor-targeted delivery of nanomedicine Journal of Controlled Release 337,546-556頁 (共著)
4.	2021/10	論文	Peptidyl-prolyl cis-trans isomerase A participates in the selenium transport into the rat brain Journal of Biological Inorganic Chemistry 26,933-945頁 (共著)
5.	2020/02	論文	Highly effective anti-tumor nanomedicines based on HPMA copolymer conjugates with pirarubicin prepared by controlled RAFT polymerization Acta Biomaterialia 106,256-266頁 (共著)
6.	2020/04	論文	Discovery of INCENP-derived small peptides for cancer imaging and treatment targeting survivin Cancer Science 111 (4),1357-1366頁 (共著)
7.	2019/12	論文	Development of radioiodinated benzofuran derivatives for in vivo imaging of prion deposits in the brain ACS Infectious Diseases 5 (12),2003-2013頁 (共著)
8.	2019/08	論文	Superior penetration and cytotoxicity of HPMA copolymer conjugates of pirarubicin in tumor cell spheroid Molecular Pharmaceutics 16 (8),3452-3459頁 (共著)
9.	2018/10	論文	Separation of selenium species in Japanese littleneck clam ‘Asari’ (Ruditapes philippinarum) and in vitro assessment of their bioavailability BPB Reports 1 (2),40-46頁 (共著)
10.	2018/12	論文	In vitro assessment of bioavailability of selenium in Niboshi processed from Japanese anchovy Food Chemistry 269,436-441頁 (共著)
11.	2018/12	論文	Synthesis and characterization of radioiodinated 3-phenethyl-2-indolinone derivatives for SPECT imaging of survivin in tumors Bioorganic and Medicinal Chemistry 26 (12),3111-3116頁 (共著)
12.	2018/04	論文	Cardiac myoglobin participates in the metabolic pathway of selenium in rats Metallomics 10 (4),614-622頁 (共著)
13.	2018/04	論文	Preparation and in vitro analysis of human serum albumin nanoparticles loaded with anthracycline derivatives Chemical and Pharmaceutical Bulletin 66 (4),382-390頁 (共著)
14.	2018/02	論文	Selenoprotein L-inspired nano-vesicular peroxidase mimics based on amphiphilic diselenides Colloids and Surfaces B: Biointerfaces 162,172-178頁 (共著)
15.	2017/11	論文	Characterization of selenium species in the Shijimi clam Chemical and Pharmaceutical Bulletin 65 (11),1045-1050頁 (共著)
16.	2017/05	論文	Amyloid formation characteristics of GNNQQNY from yeast prion protein Sup35 and its seeding with heterogeneous polypeptides Colloids and Surfaces B: Biointerfaces 149,72-79頁 (共著)
17.	2017/04	論文	Development of a ⁶⁸Ge/⁶⁸Ga generator system using polysaccharide polymers and its application in PET imaging of tropical infectious diseases ACS Omega 2 (4),1400-1407頁 (共著)
18.	2017/04	論文	Hyaluronic acid-zinc protoporphyrin IX conjugates for photodynamic antitumor therapy Journal of Nanomedicine & Nanotechnology 8 (2),440 (共著)
19.	2017/02	論文	Development of radioiodinated acridine derivatives for in vivo imaging of prion deposits in the brain Bioorganic & Medicinal Chemistry 25 (3),1085-1093頁 (共著)
20.	2016/12	論文	Pronounced cellular uptake of pirarubicin versus that of other anthracyclines: Comparison of HPMA copolymer conjugates of pirarubicin and oxorubicin Molecular Pharmaceutics 13 (12),4106-4115頁 (共著)
21.	2016/07	論文	Synthesis of nanovesicular glutathione peroxidase mimics with a selenenylsulfide-bearing lipid ACS Omega 1 (1),58-65頁 (共著)
22.	2016/02	論文	Synthesis and evaluation of a radioiodinated 4,6-diaryl-3-cyano-2-pyridinone derivative as a survivin targeting SPECT probe for tumor imaging Bioorganic & Medicinal Chemistry Letters 26 (3),999-1004頁 (共著)
23.	2016/01	論文	A comprehensive analysis of selenium-binding proteins in the brain using its reactive metabolite Chemical & Pharmaceutical Bulletin 64 (1),52-58頁 (共著)
24.	2015/12	論文	Characterisation of radioiodinated flavonoid derivatives for SPECT imaging of cerebral prion deposits Scientific Reports (共著)
25.	2015/08	著書	Chemistry and biochemistry: Selenium species in fish (Chapter 5) Food and Nutritional Components in Focus, No 9, Selenium - Chemistry, Analysis, Function and Effects,81-99頁 (共著)
26.	2015/08	論文	Development of alkoxy styrylchromone derivatives for imaging of cerebral amyloid-β plaques with SPECT Bioorganic & Medicinal Chemistry Letters 25 (16),3363-3367頁 (共著)
27.	2015/06	論文	An effective method for profiling the selenium‑binding proteins using its reactive metabolic intermediate Journal of Biological Inorganic Chemistry 20 (5),781-789頁 (共著)
28.	2014/05	論文	Synthesis and evaluation of ethyleneoxylated and allyloxylated chalcone derivatives for imaging of amyloid β plaques by SPECT Bioorganic & Medicinal Chemistry 22 (9),2622-2628頁 (共著)
29.	2013/12	著書	Selenotrisulfide as a metabolic intermediate in biological systems (Chapter 10) ACS Symposium Series 1152,201-211頁 (共著)
30.	2013/07	論文	Improved membrane fluidity of ionic polysaccharide bead-supported phospholipid bilayer membrane systems Colloids and Surfaces B: Biointerfaces 107,90-96頁 (共著)
31.	2013/05	論文	Elevated amyloid-β plaque deposition in dietary selenium-deficient Tg2576 transgenic mice Metallomics 5 (5),479-483頁 (共著)
32.	2013/02	論文	Synthesis and biological evaluation of radio iodinated quinacrine-based derivatives for SPECT imaging of Aβ plaques European Journal of Medicinal Chemistry 60,469-478頁 (共著)