教員情報 - 池田　剛

イケダ　ツヨシ Ikeda Tsuyoshi
池田　剛

所属薬学部薬学科

職種教授

著書・論文歴
1.	2025	論文	Guanidinylated Chitosan as a Multifunctional Enhancer for Improved Flurbiprofen Delivery. Biological & pharmaceutical bulletin 48 (8),1246-1254 (共著)
2.	2024/09	論文	Rapid formation of N ε-(carboxymethyl)lysine (CML) from ribose depends on glyoxal production by oxidation. RSC chemical biology 5 (11),1140-6 (共著)
3.	2024/07	論文	Multimodal inhibitory effect of matcha on Porphyromonas gingivalis. Microbiology spectrum 12 (7),e0342623 (共著)
4.	2024	論文	Prenylflavonoids isolated from Epimedii Herba show inhibition activity against advanced glycation end-products. Frontiers in chemistry 12,1407934 (共著)
5.	2023/08	論文	The unique activity of saponin: Induction of cytotoxicity in HTLV-1 infected cells. Bioorganic & medicinal chemistry 91,117408 (共著)
6.	2023/05	論文	Onionin A inhibits small-cell lung cancer proliferation through suppressing STAT3 activation induced by macrophages-derived IL-6 and cell-cell interaction with tumor-associated macrophage. Human cell 36 (3),1068-1080 (共著)
7.	2023/04	論文	Garlicnin B1, an Active Cyclic Sulfide from Garlic, Exhibits Potent Anti-Inflammatory and Anti-Tumor Activities. Antioxidants (Basel, Switzerland) 12 (4) (共著)
8.	2022/01	論文	A new steroidal glycoside from the fruits of Solanum myriacanthum. Natural product research 36 (1),326-333 (共著)
9.	2022	論文	Dual Inhibitory Activity of Petroselinic Acid Enriched in Fennel Against Porphyromonas gingivalis. Frontiers in microbiology 13,816047 (共著)
10.	2021/10	論文	Curry Leaf Triggers Cell Death of P. gingivalis with Membrane Blebbing. Pathogens (Basel, Switzerland) 10 (10) (共著)
11.	2005/05	論文	A new tomato pregnane glycoside from the overripe fruits. Chemical & pharmaceutical bulletin 53 (5),584-5 (共著)
12.	2005/07	論文	Tomato new sapogenols, isoesculeogenin A and esculeogenin B. Chemical & pharmaceutical bulletin 53 (7),839-40 (共著)
13.	2005/09	論文	Anti-herpes virus type 1 activity of oleanane-type triterpenoids. Biological & pharmaceutical bulletin 28 (9),1779-81 (共著)
14.	2005/09	論文	New Bisabolane-Type Sesquiterpenes from the Aerial Parts of Lippia dulcis. Chemical & pharmaceutical bulletin 53 (9),1175-7 (共著)
15.	2005/09	論文	Three unusual 22-beta-O-23-hydroxy-(5 alpha)-spirostanol glycosides from the fruits of Solanum torvum. Chemical & pharmaceutical bulletin 53 (9),1122-5 (共著)
16.	2005/10	論文	Iridoid glucosides from the fruit of Genipa americana. Chemical & pharmaceutical bulletin 53 (10),1342-4 (共著)
17.	2006	論文	Chemical Trans-Glycosylation of Bioactive Glycolinkage: Synthesis of an α-Lycotetraosly Cholesterol. Tetrahedron Lett. 47,4355-4359 (共著)
18.	2006/02	論文	Steroidal alkaloid glycosides, esculeosides C and D, from the ripe fruit of cherry tomato. Chemical & pharmaceutical bulletin 54 (2),237-9 (共著)
19.	2006/02	論文	Steroidal glycosides from the underground parts of Solanum sodomaeum. Chemical & pharmaceutical bulletin 54 (2),230-3 (共著)
20.	2006/09	論文	Metabolism of tomato steroidal glycosides in humans. Chemical & pharmaceutical bulletin 54 (9),1312-4 (共著)
21.	2006/10	論文	Acyclic diterpene glycosides, capsianosides VIII, IX, X, XIII, XV and XVI from the fruits of Paprika Capsicum annuum L. var. grossum BAILEY and Jalapeño Capsicum annuum L. var. annuum. Chemical & pharmaceutical bulletin 54 (10),1365-9 (共著)
22.	2006/10	論文	Bisabolane-type sesquiterpenes from the aerial parts of Lippia dulcis. Journal of natural products 69 (10),1417-20 (共著)
23.	2006/10	論文	Cucurbitane glycosides from unripe fruits of Lo Han Kuo (Siraitia grosvenori). Chemical & pharmaceutical bulletin 54 (10),1425-8 (共著)
24.	2006/10	論文	New iridoid glucosides from the aerial parts of Verbena brasiliensis. Chemical & pharmaceutical bulletin 54 (10),1421-4 (共著)
25.	2006/10	論文	Steroidal glycosides and aromatic compounds from Smilax riparia. Chemical & pharmaceutical bulletin 54 (10),1451-4 (共著)
26.	2007/04	論文	Three new monoterpenoids from the fruit of Genipa americana. Chemical & pharmaceutical bulletin 55 (4),632-4 (共著)
27.	2007/04	論文	Two new steroid glycosides and a new sesquiterpenoid glycoside from the underground parts of Trillium kamtschaticum. Chemical & pharmaceutical bulletin 55 (4),551-6 (共著)
28.	2007/07	論文	alpha-Tomatine, the major saponin in tomato, induces programmed cell death mediated by reactive oxygen species in the fungal pathogen Fusarium oxysporum. FEBS letters 581 (17),3217-22 (共著)
29.	2007/07	論文	Cucurbitane glycosides from unripe fruits of Siraitia grosvenori. Chemical & pharmaceutical bulletin 55 (7),1082-6 (共著)
30.	2007/07	論文	Distinction of absolute configuration at C-22 of C-23-hydroxyspirostane and C-23-hydroxyspirosolane glycosides. Chemical & pharmaceutical bulletin 55 (7),1079-81 (共著)
31.	2007/07	論文	Efficient conversion of tomatidine into neuritogenic pregnane derivative. Chemical & pharmaceutical bulletin 55 (7),1077-8 (共著)
32.	2007/07	論文	Three new steroid glycosides from the underground parts of Trillium kamtschaticum. Chemical & pharmaceutical bulletin 55 (7),1093-6 (単著)
33.	2007/08	論文	Acyclic diterpene glycosides, capsianosides C, D, E, F and III, from the fruits of hot red pepper Capsicum annuum L. used in Kimchi and their revised structures. Chemical & pharmaceutical bulletin 55 (8),1151-6 (共著)
34.	2007/08	論文	Iridoids from the green leaves of Eucommia ulmoides Journal of natural products 70 (8),1312-6 (共著)
35.	2007/11	論文	Esculeogenin A, a new tomato sapogenol, ameliorates hyperlipidemia and atherosclerosis in ApoE-deficient mice by inhibiting ACAT. Arteriosclerosis, thrombosis, and vascular biology 27 (11),2400-6 (共著)
36.	2007/11	論文	Synthesis of neosaponins and neoglycolipids containing a chacotriosyl moiety. Carbohydrate research 342 (15),2182-91 (共著)
37.	2008/01	論文	DPPH radical-scavenging effect on some constituents from the aerial parts of Lippia triphylla. Journal of natural medicines 62 (1),101-6 (共著)
38.	2008/01	論文	Two new lignan glucosides from the fruit of Vitex cannabifolia. Journal of natural medicines 62 (1),47-51 (共著)
39.	2008/04	論文	Some natural compounds enhance N epsilon-(carboxymethyl)lysine formation. Annals of the New York Academy of Sciences 1126,152-4 (共著)
40.	2008/04	論文	Three new acyclic diterpene glycosides from the aerial parts of paprika and pimiento. Chemical & pharmaceutical bulletin 56 (4),582-4 (共著)
41.	2008/04	論文	Usefulness of antibodies for evaluating the biological significance of AGEs. Annals of the New York Academy of Sciences 1126,38-41 (共著)
42.	2008/06	論文	Efficient synthesis of alpha- and beta-chacotriosyl glycosides using appropriate donors, and their cytotoxic activity. Carbohydrate research 343 (8),1309-15 (共著)
43.	2008/07	論文	A new homostilbene and two new homoisoflavones from the bulbs of Scilla scilloides. Chemical & pharmaceutical bulletin 56 (7),1022-5 (共著)
44.	2008/07	論文	A pregnane glycoside from overripe tomato. Chemical & pharmaceutical bulletin 56 (7),1013-4 (共著)
45.	2008/07	論文	Conversion of esculeoside A into esculeogenin B. Chemical & pharmaceutical bulletin 56 (7),926-9 (共著)
46.	2008/07	論文	Mechanism for conversion of spirosolane derivative into pregnane. Chemical & pharmaceutical bulletin 56 (7),1015-7 (共著)
47.	2008/07	論文	New C(28) steroidal glycosides from Tubocapsicum anomalum. Chemical & pharmaceutical bulletin 56 (7),1038-40 (共著)
48.	2008/08	論文	Studies on the constituents of Gueldenstaedtia multiflora. Chemical & pharmaceutical bulletin 56 (8),1138-42 (共著)
49.	2008/10	論文	A new steroidal glycoside and a new phenyl glycoside from a ripe cherry tomato. Chemical & pharmaceutical bulletin 56 (10),1499-501 (共著)
50.	2008/11	論文	Five new diterpenoids, viteagnusins A--E, from the fruit of Vitex agnus-castus. Chemical & pharmaceutical bulletin 56 (11),1621-4 (共著)
51.	2009	著書	生薬学へのいざない─生薬学は今日の医療にどう役立つのか─
52.	2009/01	論文	A new lignan glucoside from the stems of Callicarpa japonica Thunb. var. luxurians Rehd. Journal of natural medicines 63 (1),86-90 (共著)
53.	2009/04	論文	Involvement of ethylene in the accumulation of esculeoside A during fruit ripening of tomato (Solanum lycopersicum). Journal of agricultural and food chemistry 57 (8),3247-52 (共著)
54.	2009/06	論文	Steroidal glycosides from the fruits of Solanum viarum. Chemical & pharmaceutical bulletin 57 (6),632-5 (共著)
55.	2009/07	論文	A new diterpenoid and a new triterpenoid glucosyl ester from the leaves of Callicarpa japonica Thunb. var. luxurians Rehd. Journal of natural medicines 63 (3),318-22 (共著)
56.	2009/07	論文	A new spirostanol glycoside from fruits of Solanum indicum L. Chemical & pharmaceutical bulletin 57 (7),747-8 (共著)
57.	2009/07	論文	Five new steroidal glycosides from the stems of Solanum sodomaeum. Chemical & pharmaceutical bulletin 57 (7),759-63 (共著)
58.	2009/07	論文	Studies on the constituents of whole plants of Youngia japonica. Chemical & pharmaceutical bulletin 57 (7),719-23 (共著)
59.	2009/07	論文	Two new acyclic diterpene glycosides from fruits of Habanero, Capsicum chinense. Chemical & pharmaceutical bulletin 57 (7),730-3 (共著)
60.	2009/08	論文	Two new cucurbitane-type glycosides obtained from roots of Siraitia grosvenori SWINGLE. Chemical & pharmaceutical bulletin 57 (8),870-2 (共著)
61.	2009/09	論文	Astragalosides isolated from the root of astragalus radix inhibit the formation of advanced glycation end products. Journal of agricultural and food chemistry 57 (17),7666-72 (共著)
62.	2009/10	論文	Three new diterpenoids from the fruit of Vitex agnus-castus. Chemical & pharmaceutical bulletin 57 (10),1132-5 (共著)
63.	2010/05	論文	[Fascination with natural glycosides]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 130 (5),679-86 (共著)
64.	2010/06	論文	Aaptamine, an alkaloid from the sponge Aaptos suberitoides, functions as a proteasome inhibitor. Bioorganic & medicinal chemistry letters 20 (11),3341-3 (共著)
65.	2010/07	論文	Onionin A from Allium cepa inhibits macrophage activation. Journal of natural products 73 (7),1306-8 (共著)
66.	2010/08	論文	HSP70 inducers from Chinese herbs and their effect on melanin production. Experimental dermatology 19 (8),e340-2 (共著)
67.	2010/08	論文	Notoamide O, a structurally unprecedented prenylated indole alkaloid, and notoamides P-R from a marine-derived fungus, Aspergillus sp. Journal of natural products 73 (8),1438-40 (共著)
68.	2010/10	論文	Study of constituents of Veronicastrum villosulum. Journal of natural medicines 64 (4),510-3 (共著)
69.	2010/10	論文	The tomato saponin, esculeoside A. Journal of natural products 73 (10),1734-41 (共著)
70.	2010/10	論文	Three new aromatic glycosides from the ripe fruit of cherry tomato. Journal of natural medicines 64 (4),500-5 (共著)
71.	2010/11	論文	Acylated glycosides of hydroxy fatty acid methyl esters generated from the crude resin glycoside (pharbitin) of seeds of Pharbitis nil by treatment with indium(III) chloride in methanol. Journal of natural products 73 (11),1846-52 (共著)
72.	2010/11	論文	Effect of natural compounds on human macrophage activation 炎症・再生 : 日本炎症・再生医学会雑誌 = Inflammation and regeneration 30 (6),520-523頁 (共著)
73.	2011	論文	A new diterpenoid glucoside and two new diterpenoids from the fruit of Vitex agnus-castus. Chemical & pharmaceutical bulletin 59 (3),392-6 (共著)
74.	2011	論文	Anti-obesity compounds in green leaves of Eucommia ulmoides. Bioorg. Med. Chem. Lett. 21,1786-1791
75.	2011	論文	Four new iridoid glucosides from Ajuga reptans. Chemical & pharmaceutical bulletin 59 (8),1065-8 (共著)
76.	2011	論文	Garlicnin A from the fraction regulating macrophage activation of Allium sativum. Chemical & pharmaceutical bulletin 59 (11),1340-3 (共著)
77.	2011	論文	Isolation of salsolinol, a tetrahydroisoquinoline alkaloid, from the marine sponge Xestospongia cf. vansoesti as a proteasome inhibitor. Chemical & pharmaceutical bulletin 59 (2),287-90 (共著)
78.	2011/01	論文	Content variations of the tomato saponin esculeoside A in various processed tomatoes. Journal of natural medicines 65 (1),176-9 (共著)
79.	2011/01	論文	Corosolic acid inhibits glioblastoma cell proliferation by suppressing the activation of signal transducer and activator of transcription-3 and nuclear factor-kappa B in tumor cells and tumor-associated macrophages. Cancer science 102 (1),206-11 (共著)
80.	2011/01	論文	Study of the chemical constituents of Pruni Cortex and its related parts. Journal of natural medicines 65 (1),166-71 (共著)
81.	2011/04	論文	Changes in esculeoside A content in different regions of the tomato fruit during maturation and heat processing. Journal of agricultural and food chemistry 59 (8),4104-10 (共著)
82.	2011/04	論文	Lucidenic acids-rich extract from antlered form of Ganoderma lucidenhances TNFα induction in THP-1 monocytic cells possibly via its modulation of MAP kinases p38 and JNK. Biochemical and biophysical research communications 408 (1),18-24 (共著)
83.	2011/04	論文	Natural compounds containing a catechol group enhance the formation of Nε-(carboxymethyl)lysine of the Maillard reaction. Free radical biology & medicine 50 (7),883-91 (共著)
84.	2011/05	論文	Triterpenoids isolated from Zizyphus jujuba inhibit foam cell formation in macrophages. Journal of agricultural and food chemistry 59 (9),4544-52 (共著)
85.	2011/12	論文	Oleanolic acid inhibits macrophage differentiation into the M2 phenotype and glioblastoma cell proliferation by suppressing the activation of STAT3. Oncology reports 26 (6),1533-7 (共著)
86.	2012	論文	Garlicnins B(1), C(1), and D, from the fraction regulating macrophage activation of Allium sativum. Chemical & pharmaceutical bulletin 60 (6),747-51 (共著)
87.	2012/03	論文	Tomatidine, a tomato sapogenol, ameliorates hyperlipidemia and atherosclerosis in apoE-deficient mice by inhibiting acyl-CoA:cholesterol acyl-transferase (ACAT). Journal of agricultural and food chemistry 60 (10),2472-9 (共著)
88.	2012/04	論文	Purification and characterization of HSP-inducers from Eupatorium lindleyanum. Biochemical pharmacology 83 (7),909-22 (共著)
89.	2013	著書	機能性配糖体の合成と応用,147-158頁 (単著)
90.	2013	論文	Identification and Biological Activity of Antifungal Saponins from Shallot (Allium cepa L. Aggregatum Group) Journal of Agricultural and Food Chemistry 61 (31),7440-7445頁 (共著)
91.	2013	論文	The Chemistry and Bioactivity of Eucommia ulmoides Oliver Leaves Study in Natural Product Chemistry (共著)
92.	2013	その他	トマトサポニンの機能性と反応天然有機化合物討論会講演要旨集 55 (0),PosterP-4頁 (共著)
93.	2013/04	論文	Aginoside saponin, a potent antifungal compound, and secondary metabolite analyses from Allium nigrum L. Phytochemistry Letters 6 (2),274-280頁 (共著)
94.	2013/04	論文	Screening of promising chemotherapeutic candidates from plants against human adult T-cell leukemia/lymphoma (II): apoptosis of antiproliferactive principle (24,25-dihydrowithanolide D) against ATL cell lines and structure-activity relationships with withanolides isolated from solanaceous plants. Journal of natural medicines 67 (2),415-20 (共著)
95.	2013/06	論文	Corosolic acid impairs tumor development and lung metastasis by inhibiting the immunosuppressive activity of myeloid-derived suppressor cells. Molecular nutrition & food research 57 (6),1046-54 (共著)
96.	2013/07	論文	Cyclic sulfoxides garlicnins B2, B3, B4, C2, and C3 from Allium sativum. Chemical & pharmaceutical bulletin 61 (7),695-9 (共著)
97.	2013/07	論文	Saponins esculeosides B-1 and B-2 in Italian canned tomatoes. Chemical & pharmaceutical bulletin 61 (7),764-7 (共著)
98.	2013/08	論文	Identification and biological activity of antifungal saponins from shallot ( Allium cepa L. Aggregatum group). Journal of agricultural and food chemistry 61 (31),7440-5 (共著)
99.	2013/12	論文	Corosolic acid enhances the antitumor effects of chemotherapy on epithelial ovarian cancer by inhibiting signal transducer and activator of transcription 3 signaling. Oncology letters 6 (6),1619-1623 (共著)
100.	2014	論文	Acyclic sulfides, garlicnins L-1-L-4, E, and F, from Allium sativum. Chemical & pharmaceutical bulletin 62 (5),477-82 (共著)
101.	2014/05	論文	Conversion of tomato saponins to pregnane derivatives. Chemical & pharmaceutical bulletin 62 (5),483-7 (共著)
102.	2014/11	論文	Isolation and characterization of new onionins A2 and A3 from Allium cepa, and of onionins A1, A2, and A3 from Allium fistulosum. Chemical & pharmaceutical bulletin 62 (11),1141-5 (共著)
103.	2015	論文	Saponins, Esculeosides B-1 and B-2, in Tomato Juice and Sapogenol, Esculeogenin B1. Chemical & pharmaceutical bulletin 63 (10),848-50 (共著)
104.	2015/02	論文	A new hemiterpene glycoside from the ripe tomatoes. Natural product research 29 (3),262-7 (共著)
105.	2015/04	論文	Identification of HSP70-inducing activity in Arnica montana extract and purification and characterization of HSP70-inducers. Journal of dermatological science 78 (1),67-75 (共著)
106.	2016/04	論文	Two new bicyclic sulfoxides from Welsh onion. Journal of natural medicines 70 (2),260-5 (共著)
107.	2016/04	論文	Two new prenylflavonoids from Epimedii Herba and their inhibitory effects on advanced glycation end-products. Journal of natural medicines 70 (2),290-5 (共著)
108.	2016/06	論文	Eucommia ulmoides extracts prevent the formation of advanced glycation end products. Food & Function 7 (6),2566-2573頁 (共著)
109.	2016/07	論文	Onionin A inhibits ovarian cancer progression by suppressing cancer cell proliferation and the protumour function of macrophages. Scientific reports 6,29588 (共著)
110.	2016/10	論文	Antimicrobial and immunomodulatory activities of flavonol glycosides isolated from Atriplex halimus L. herb Journal of Pharmaceutical Sciences and Research 8 (10),1159-1168頁 (共著)
111.	2016/11	論文	Onionin A, a sulfur-containing compound isolated from onions, impairs tumor development and lung metastasis by inhibiting the protumoral and immunosuppressive functions of myeloid cells. Molecular nutrition & food research 60 (11),2467-2480 (共著)
112.	2017	論文	Atypical Cyclic Sulfides, Garlicnins G, I, and J, Extracted from Allium sativum. Chemical & pharmaceutical bulletin 65 (1),102-106 (共著)
113.	2017/02	論文	Inhibition of gingipains and Porphyromonas gingivalis growth and biofilm formation by prenylated flavonoids J. Periodontal Res. 52 (1),89-96頁 (共著)
114.	2017/03	論文	Antitumor Allium sulfides Chemical & Pharmaceutical Bulletin 65 (3),209-217頁 (共著)
115.	2017/09	論文	Apoptosis induction of poly-S-nitrosated human serum albumin in resistant solid tumor under hypoxia can be restored by phosphodiesterase 5 inhibition. Nitric oxide : biology and chemistry 69,28-34 (共著)
116.	2018/01	論文	Natural compounds that regulate lymph node sinus macrophages: Inducing an anti-tumor effect by regulating macrophage activation. Journal of clinical and experimental hematopathology : JCEH 58 (1),17-23 (共著)
117.	2018/01	論文	New cyclic sulfides extracted from Allium sativum: garlicnins P, J2, and Q. Journal of natural medicines 72 (1),335-341 (共著)
118.	2018/01	論文	New cyclic sulfides, garlicnins I2, M, N, and O, from Allium sativum. Journal of natural medicines 72 (1),326-331 (共著)
119.	2018/08	論文	Rapid bactericidal action of propolis on Porphyromonas gingivalis Journal of Dental Research 97 (8),928-936頁 (共著)
120.	2018/08	論文	Self-assembly of [Au(CN)2]- complexes with tomato (Solanum lycopersicum) steroidal alkaloid glycosides to form sheet or tubular structures Chemistry Letters 47 (8),1010-1013頁 (共著)
121.	2019/07	論文	A natural anti-periodontitis agent, epimedokoreanin B, inhibits virulence activities of gingipains from Porphyromonas gingivalis. Bioscience, biotechnology, and biochemistry 83 (7),1382-1384 (共著)
122.	2020	論文	Flavonoid Compounds Contained in Epimedii Herba Inhibit Tumor Progression by Suppressing STAT3 Activation in the Tumor Microenvironment Front Pharmacol. 11 (262),1-15頁 (共著)
123.	2020/10	論文	Drosera tokaiensis extract containing multiple phenolic compounds inhibits the formation of advanced glycation end-products. Archives of biochemistry and biophysics 693,108586 (共著)
124.	2021/05	論文	Supramolecular Assembly of Hybrid Pt(II) Porphyrin/Tomatine Analogues with Different Nanostructures and Cytotoxic Activities. ACS omega 6 (20),13284-13292 (共著)
125.	2021/09	論文	Thiolane-type sulfides from garlic, onion, and Welsh onion. Journal of natural medicines 75 (4),741-751 (共著)