Faculty Information - Kuniyasu Akihiko

Kuniyasu Akihiko

Department / Course FACULTY OF PHARMACEUTICAL SCIENCES Department of Pharmaceutical Sciences

Job

Book and thesis
1.	1996	Papers	Identification of binding sites for calcium channel antagonists. Jpn. Heart J. 37,,pp.643-650 (Co-authored)
2.	1998	Papers	Photochemical identification of transmembrane segment IVS6 as the binding region of semotiadil, a new modulator for the L-type voltage-dependent Ca2+ channel. J. Biol. Chem. 273,pp.4635-4641 (Co-authored)
3.	1999	Papers	[³⁵S] S-[5-(4-benzoylphenyl) pentyl] glutathione: a versatile radioligand targeting GS-X pumps with the ability of photoaffinity labeling. Bioorg. Med. Chem. Lett. 9,pp.2661-2666 (Co-authored)
4.	1999	Papers	A new scorpion toxin (BmK-PL) stimulates Ca²⁺-release channel activity of the skeletal-muscle ryanodine receptor by an indirect mechanism. Biochem. J. 339,pp.343-350 (Co-authored)
5.	2000	Papers	Glibenclamide acts as an inhibitor of acyl-CoA:cholesterol acyltransferase enzyme. Biochem. Biophys. Res. Commun. 277,pp.417-422 (Co-authored)
6.	2001	Papers	Asymmetric arrangement of auxiliary subunits of skeletal muscle voltage-gated L-type Ca²⁺ channel. Biochem. Biophys. Res. Commun. 282,pp.284-291 (Co-authored)
7.	2001	Papers	Co-induction of arginino- succinate synthetase, cationic amino acid transporter-2, and nitric oxide synthase in activated murine microglial cells. Brain Res. Mol. Brain Res. 90,pp.165-173 (Co-authored)
8.	2002	Papers	Adipocytes recognize and degrade oxidized low density lipoprotein through CD36. Biochem. Biophys. Res. Commun. 295,pp.319-323 (Co-authored)
9.	2002	Papers	Efficient identification of photolabelled amino acid residues by combining immunoaffinity purification with MS: revealing the semotiadil-binding site and its relevance to binding sites for myristates in domain III of human serum albumin Biochem. J. 363,pp.223-232 (Co-authored)
10.	2003	Papers	Advanced glycation end products (AGE) inhibit scavenger receptor class B type I-mediated reverse cholesterol transport: a new crossroad of AGE to cholesterol metabolism. J. Atheroscler. Thromb. 10,pp.1-6 (Co-authored)
11.	2003	Papers	CD36-mediated endocytic uptake of advanced glycation end products (AGE) in mouse 3T3-L1 and human subcutaneous adipocytes. FEBS Lett. 537,pp.85-90 (Co-authored)
12.	2003	Papers	Cloning, expression and tissue distribution of a tetrameric form of pig carbonyl reductase. Chem. Biol. Interact. 143-144,pp.353-361 (Co-authored)
13.	2003	Papers	Molecular assembly and subcellular distribution of ATP-sensitive potassium channel proteins in rat hearts. FEBS Lett. 552,pp.259-263 (Co-authored)
14.	2003	Papers	Photochemical identification of the binding region for (S)-semotiadil on sodium channels: comparison with that for (R)-semotiadil on skeletal muscle calcium channel. Heterocycles 59,pp.613-622 (Co-authored)
15.	2004	Papers	Advanced glycation end products- modified proteins and oxidized LDL mediate down-regulation of leptin in mouse adipocytes via CD36. Biochem. Biophys. Res. Commun. 325,pp.151-156 (Co-authored)
16.	2005	Papers	Characterization of benzodiazepine binding site on human a1-acid glycoprotein using flunitrazepam as a photolabeling agent. Biochim. Biophys. Acta 1725,pp.385-393 (Co-authored)
17.	2005	Papers	Proteasomal degradation of Kir6.2 channel protein and its inhibition by a Na⁺ channel blocker aprindine. Biochem. Biophys. Res. Commun. 331,pp.1001-1006 (Co-authored)
18.	2005	Papers	Stoichiometry and binding site analysis of ligand-human serum albumin complex by photoaffinity labeling and mass spectrometry. J. Mass Spectrom. Soc. Jpn. 53,pp.18-24 (Co-authored)
19.	2006	Papers	Ligand-directed surface profiling of human cancer cells with combinatorial peptide libraries. Cancer Res. 66,pp.34-40 (Co-authored)
20.	2007	Papers	A previously unrecognized protein-protein interaction between TWEAK and CD163: Potential biological implications. J. Immunol. 178,pp.8183-8194 (Co-authored)
21.	2008	Papers	Combinatorial targeting of the macropinocytotic pathway in leukemia and lymphoma cells. J. Biol. Chem. 283,pp.11752-11762 (Co-authored)
22.	2008	Papers	Constitutive overexpression of P-glycoprotein, rather than breast cancer resistance protein or organic cation transporter 1, contributes to acquisition of imatinib-resistance in K562 cells. Pharm. Res. 25,pp.827-835 (Co-authored)
23.	2009	Papers	A synthetic approach to develop peptide inhibitors selective for brain-type sodium channels on the basis of pompilidotoxin structure. Heterocycles 79,pp.925-933 (Co-authored)
24.	2009	Papers	Linkage between phosphorylation of the origin recognition complex and its ATP-binding activity in Saccharomyces cerevisiae. J. Biol. Chem. 284,pp.3396-3407 (Co-authored)
25.	2009	Papers	Marked induction of inducible nitric oxide synthase and tumor necrosis factor-α in rat CD40⁺ microglia by comparison to CD40 microglia. J. Neuroimmunol. 208,pp.70-79 (Co-authored)
26.	2009	Papers	Oral administration of synthetic retinoid Am80(Tamibarotene) decreases brain β-amyloid peptides in APP23 mice. Biol. Pharm. Bull. 32,pp.1307-1309 (Co-authored)
27.	2010	Papers	Contribution of BCR-ABL-independent activation of ERK1/2 to acquired imatinib resistance in K562 chronic myeloid leukemia cells. Cancer Sci. 101,pp.137-142 (Co-authored)
28.	2010	Papers	Interconversion between pure chemotactic ligands and chemoattractant/secretagogue ligands of neutrophil C5_a receptor by a single amino acid substitution. J. Leukoc. Biol. 87,pp.965-975 (Co-authored)
29.	2010	Papers	Three-dimensional structure of α1-β complex in skeletal muscle dihydropyridine receptor by single particle electron microscopy. J. Electron Microsc. 59,pp.215-226 (Co-authored)
30.	2010/02	Papers	Notch-1 fragment peptide induces autophagy and caspase-independent cell death in leukemia cell lines An AACR special conference series: Cell Death Mechanisms and Cancer Therapy,pp.71 (Co-authored)
31.	2010/10	Papers	Cell-selective cell penetrating peptide as an intelligent molecular carrier BIT 1st Annual World Congress of NanoMedicine-2010 (Co-authored)
32.	2011	Papers	Oxidized LDL and lysophosphatidylcholine stimulate plasminogen activator inhibitor-1 expression through reactive oxygen species generation and ERK1/2 activation in 3T3-L1 adipocytes. Biochim. Biophys. Acta 1811,pp.153-162 (Co-authored)
33.	2011	Papers	Quantitative analysis of cysteine-34 on the aniti-oxidative properties of human serum albumin in hemodialysis patients J. Pharm. Sci. 100,pp.3968-3976 (Co-authored)
34.	2011	Papers	Targeting neuropilin-1 in human leukemia and lymphoma. Blood 117,pp.920-927 (Co-authored)
35.	2012	Papers	Effects of C4_a on chemoattractant and secretagogue functions of the other anaphylatoxins via Gi protein-adenylyl cyclase inhibition pathway in mast cells. Int. Immunopharmacol. 12,pp.158-68 (Co-authored)
36.	2012/02	Papers	A hybrid peptide-25mer induces a caspase-independent cell death in leukemic cell lines Cell Death in Cancer,pp.21 (Co-authored)
37.	2013	Papers	Crystallization and preliminary X-ray analysis of human MTH1 with a homogeneous N-terminus Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 69,pp.45-48 (Co-authored)
38.	2014	Papers	Cooperative therapeutic action of retinoic Acid receptor and retinoid X receptor agonists in a mouse model of Alzheimer's disease. J. Alzheimers Dis. 42,pp.587-605 (Co-authored)
39.	2014/07	Papers	Hybrid peptide tat-Ram13-induced necrosis-like cell death depends on expression of PTEN in human leukemia cell lines. Eur. J. Cancer 50,pp.23-24 (Co-authored)
40.	2015	Papers	Targeting interleukin-11 receptor in leukemia and lymphoma: A functional ligand-directed study and hematopathology analysis of patient-derived specimens. Clin. Cancer Res. 21 (13),pp.3041-3051 (Co-authored)
41.	2016/11	Papers	The novel monoclonal antibody 9F5 reveals expression of a fragment of GPNMB/osteoactivin processed by furin-like protease(s) in a subpopulation of microglia in neonatal rat brain. Glia 64 (11),pp.1938-1961 (Co-authored)
42.	2017	Books	Combination of Photoaffinity Label and Site-Directed Antibody for Target Proteins Photoaffinity Labeling for Structural Probing Within Protein,pp.93-110 (Co-authored)
43.	2018/05	Papers	Design and tuning of a cell-penetrating albumin derivative as a versatile nanovehicle for intracellular drug delivery. J Control Release 10 (277),pp.23-34 (Co-authored)
44.	2018/05	Papers	The role of vimentin in the tumor marker Nup88-dependent multinucleated phenotype. BMC Cancer 18 (1),pp.519 (Co-authored)
45.	2018/05	Papers	Therapeutic targeting of membrane-associated GRP78 in leukemia and lymphoma: preclinical efficacy in vitro and formal toxicity study of BMTP-78 in rodents and primates Pharmacogenomics J 22 (18),pp.436-443 (Co-authored)
46.	2021/11	Papers	Overexpression of the nucleoporin Nup88 stimulates migration and invasion of HeLa cells. Histochem. Cell. Biol. 156,pp.409-421 (Co-authored)
47.	2021/09	Papers	Acid-responsive HPMA copolymer-bradykinin conjugate enhances tumor-targeted delivery of nanomedicine J Control Release 10 (337),pp.546-556 (Co-authored)