Faculty Information - Takeya Hiroyuki

Takeya Hiroyuki

Department / Course FACULTY OF BIOTECHNOOLOGY AND LIFE SCIENCE Department of Biotechnology and Life Sciences

Job

Book and thesis
1.	1988	Papers	A new trisaccharide sugar chain linked to a serine residue in blood coagulation factor VII and IX. J Biochem 104: 867-868, 1988 (Co-authored)
2.	1988	Papers	Bovine factor VII. Its purification and complete amino acid sequence. J Biol Chem 263:7494-7502, 1988 (Co-authored)
3.	1988	Papers	Molecular analysis of β-thalassemia in Asia. J Biomed & Lab Sci 1:9-16, 1988 (Co-authored)
4.	1989	Papers	Blood clotting factor IX BM Nagoya. Substitution of arginine 180 by tryptophan and its activation by α-chymotrypsin and rat mast cell chymase. J Biol Chem 264:21257-21265, 1989 (Co-authored)
5.	1989	Papers	Primary structure of H2-proteinase, a non-hemorrhagic metalloproteinase, isolated from the venom of habu Snake, Trimeresurus flavoviridis. J Biochem 106:151-157, 1989 (Co-authored)
6.	1989	Papers	Primary structure of hemorrhagic protein, HR2a, isolated from the venom of Trimeresurus flavoviridis. J Biochem 105:847-853, 1989 (Co-authored)
7.	1989	Papers	Purification of a DNA replication terminus (ter) site-binding protein in Escherichia coli and identification of the structural gene. J Biol Chem 264:21031-21037, 1989 (Co-authored)
8.	1990	Papers	Amino acid sequence of human protein Z, a vitamin K-dependent plasma glycoprotein. Biochem Biophys Res Commun 172:1139-1144, 1990 (Co-authored)
9.	1990	Papers	Blood clotting factor IX Nagoya 3. The molecular defect of zymogen activation caused by an arginine-145 to histidine substitution. Thromb Res 60:311-320, 1990 (Co-authored)
10.	1990	Papers	Primary structure of hemorrhagic metalloproteinase, HT-2, isolated from the venom of Crotalus ruber ruber. J Biochem 108:711-719, 1990 (Co-authored)
11.	1990	Papers	Purification, structure, and biochemical properties of human O6-methylguanine-DNA methyltransferase. J Biol Chem 265:14754-14762, 1990 (Co-authored)
12.	1990	Papers	The complete amino acid sequence of hemorrhagic protein HR1B isolated from the venom of Trimeresurus flavoviridis. J Biol Chem 265:16068-16074, 1990 (Co-authored)
13.	1990	Papers	The Structure and Function Relationships of Hemorrhagic Factors Isolated from the Venoms of Trimeresurus flavoviridis and Crotalus rubber rubber. Jpn J Med Sci Biol 43: 252-253, 1990 (Co-authored)
14.	1992	Papers	Coagulation factor X activating enzyme from Russell's viper venom (RVV-X). A novel metalloproteinase with disintegrin (platelet aggregation inhibitor)-like and C-type lectin-like domains. J Biol Chem 267:14109-14117, 1992 (Co-authored)
15.	1992	Papers	Putative inositole 1,4,5-trisphosphate binding proteins in rat brain cytosol. J Biol Chem 267:6518-6525, 1992 (Co-authored)
16.	1993	Books	Structure and function of snake venom metalloproteinase family. Methods in protein sepuence analysis,pp.107-115 (Co-authored)
17.	1993	Papers	Factor IX Fukuoka. Substitution of Asn92 by His in the second epidermal growth factor-like domain results in defective interaction with factor VIIIa/X. J Biol Chem 268:24041-24046, 1993 (Co-authored)
18.	1993	Papers	Honda S, Morohashi K, Nomura M, Takeya H, Kitajima M, and Omura T: Ad4BP regulating steroidogenic P-450 gene is a member of steroid hormone receptor superfamily. J Biol Chem 268:7494-7502, 1993 (Co-authored)
19.	1993	Papers	Primary structures of platelet aggregation inhibitors (disintegrins). Autoproteolytically released from snake venom hemorrhagic metalloproteinases and new fluorogenic peptide substrates for these enzymes. J Biochem 113:473-483, 1993 (Co-authored)
20.	1993	Papers	Snake venom hemorrhagic and non-hemorrhagic metalloproteinases. In: Methods in enzymology Vol 223,pp.365-378 (Co-authored)
21.	1993	Papers	Snake venom hemorrhagic and non-hemorrhagic metalloproteinases. Methods Enzymol 223:365-378, 1993 (Co-authored)
22.	1993	Papers	The region Ser333-Arg356 of the α-chain of human C4b-binding protein is involved in the binding of complement C4b. FEBS Lett 317:228-232, 1993 (Co-authored)
23.	1994	Books	Snake venom hemorrhagic and non-hemorrhagic metalloproteinases. Their structure and function relationships. In: Biological functions of proteases and inhibitors,pp.231-252 (Co-authored)
24.	1994	Papers	Blood coagulation factor Xa interacts with a linear sequence of the kringle 2 domain of prothrombin. J Biochem 116:589-597, 1994 (Co-authored)
25.	1994	Papers	Receptor-mediated endocytosis of thrombin-antithrombin III complex by the human monocytoid cell line U937. Biochem Biophys Res Commun 200:1334-1340, 1994 (Co-authored)
26.	1994	Papers	The role of human factor X activation peptide in activation of factor X by factor IXa. J Biochem 116:335-340, 1994 (Co-authored)
27.	1994	Papers	The thrombin receptor transmits signals through a 33-kDa protein kinase in human platelets. Biochem Biophys Res Commun 203:907-913, 1994 (Co-authored)
28.	1995	Papers	cDNA cloning and deduced amino acid sequence of prothrombin activator (ecarin) from Kenyan Echis carinatus venom. Biochemistry 34:1771-1778, 1995 (Co-authored)
29.	1995	Papers	Characterization of the binding of factor Xa to fibrinogen/fibrin deribatives and localization of the factor Xa binding site on fibrinogen. Eur J Biochem 232:90-97, 1995 (Co-authored)
30.	1995	Papers	Crystallization and preliminary X-ray study of H2-proteinase from the venom of Trimeresurus flavoviridis. J Biochem 117:929-930, 1995 (Co-authored)
31.	1995	Papers	Identification of the Oligosaccharide Structures of Human Coagulation Factor X Activation Peptide at Each Glycosylation Site. Glycoconjugate J 12:173-181, 1995 (Co-authored)
32.	1996	Books	Binding sites of factor Xa on fibrinogen, fibrin and fibrin degradation products. In: Blood coagulation,fibrinolysis, and platelets,pp.33-36 (Co-authored)
33.	1996	Papers	Protein C activation in patients with non-insulin-dependent diabetes mellitus. Diabetologia 39:1455-1461, 1996 (Co-authored)
34.	1996	Papers	Purification, characterization and cDNA cloning of a novel anticoagulant of the intrinsic pathway (prolixin-S), from salivary glands of the blood sucking bug, Rhodnius prolixus. Thromb Haemost 75:573-577, 1996 (Co-authored)
35.	1996	Papers	β2-Glycoprotein I Modulates the anticoagulant activity of activated protein C on the phospholipid surface. Thromb Haemost 75:49-55, 1996 (Co-authored)
36.	1997	Books	Dilazep, an antiplatelet agent, inhibits tissue factor expression in endothelial cells. In: Recent progress in blood coagulation and fibrinolysis,pp.19-28 (Co-authored)
37.	1997	Papers	Anti-β2-glycoprotein I (β2GP1) monoclonal antibodies with lupus anticoagulant-like activity enhance the β2GPI binding to phospholipids. J Clin Invest 99:2260-2268, 1997 (Co-authored)
38.	1997	Papers	Aquired activated protein C resistance in patients with lupus anticoagulant and essential thrombocythemia. Clin Appl Thromb Hemostas 3:119-123, 1997 (Co-authored)
39.	1997	Papers	Dilazep, an antiplatelet agent, inhibits tissue factor expression in endothelial cells stimulated with tumor necrosis factor-α, thrombin, and phorbol 12-myristate 13-acetate. Blood 90:2345-2356, 1997 (Co-authored)
40.	1997	Papers	Kringle 1 domain of prothrombin interacts with factor Va during the assembly of the prothrombinase complex. Biochem J 321:729-735, 1997 (Co-authored)
41.	1998	Books	Protease that induce hemorrhage. In: The enzymes from snake venom,pp.11-38 (Co-authored)
42.	1998	Papers	Adenosine Regulates Tissue factor expression on endothelial cells. Thromb Res 91:57-64, 1998 (Co-authored)
43.	1998	Papers	Protein C anticoagulant system in patients with interstitial lung disease. Am J Respir Crit Care Med 157:1850-1854, 1998 (Co-authored)
44.	1998	Papers	Prothrombin and its derivatives stimulate motility of melanoma cells. Thromb Haemost 80:407-412, 1998 (Co-authored)
45.	1999	Papers	Changes of plasma hemostatic markers during percutaneous transluminal coronary angioplasty in patients with chronic coronary artery disease. Am J Hematol 61:238-242, 1999 (Co-authored)
46.	1999	Papers	The zymogen prothrombin stimulates cell locomotion and calcium influx in murine osteosarcoma cells by different mechanism from thrombin. Int J Oncol 15:1197-1203, 1999 (Co-authored)
47.	1999	Papers	Thrombin in the airways of asthmatic patients. Lung 177:253-262, 1999 (Co-authored)
48.	2000	Papers	Coagulation and fibrinolytic activities in 2 siblings with β2-glycoprotein I deficiency. Blood 96: 1594-1595, 2000 (Co-authored)
49.	2003	Papers	Synergistic effect of sphingosine 1-phosphate on thrombin-induced tissue factor expression in endothelial cells. Blood 102:1693-1700, 2003 (Co-authored)
50.	2006	Papers	Intratracheal gene transfer of tissue factor pathway inhibitor attenuates pulmonary fibrosis. Biochem Biophys Res Commun 339:1113-1119, 2006 (Co-authored)
51.	2008	Books	Lipid mediators and tissue factor expression. In:Recent advances in thrombosis and hemostasis,pp.133-146 (Co-authored)
52.	2008	Papers	Self-interaction of soluble and surface-bound β2-glycoprotein I and its enhancement by lupus anticoagulants. FEBS Lett 582:3308-3312, 2008 (Co-authored)
53.	2011	Papers	Effect of dibutyryl cyclic adenosine monophosphate on the gene expression of plasminogen activator inhibitor-1 and tissue factor in adipocytes. Thromb Res 128,pp.375-380 (Co-authored)
54.	2011	Papers	Sphingomyelin synthase 1-generated sphingomyelin plays an important role in transferrin trafficking and cell proliferation. J Biol Chem 286,pp.36053-36062 (Co-authored)
55.	2012	Papers	Regulation of autophagy and its associated cell death by sphingolipid rheostat J Biol Chem 287,pp.39898-39910 (Co-authored)
56.	2012	Papers	Snake venom metalloproteinases : structure, function and relevance to the mammalian ADAM/AMAMTS family proteins. Biochim Biophis Acta 1824,pp.164-176 (Co-authored)
57.	2013	Papers	An induced pluripotent stem cell-mediated and integration-free factor VIII expression system Biochem Biophys Res Commun 431,pp.336-341 (Co-authored)
58.	2021	Papers	A novel mechanism of thrombocytopenia by PS exposure through TMEM16F in sphingomyelin synthase 1 deficiency 5 (20),pp.:4265-4277 (Co-authored)