Faculty Information - Iohara Daisuke

Iohara Daisuke

Department / Course FACULTY OF PHARMACEUTICAL SCIENCES Department of Pharmaceutical Sciences

Job

Book and thesis
1.	2025	Papers	Preparation of a Stable Indomethacin Supersaturated Solution Using Hydrophobically Modified Hydroxypropylmethylcellulose and α-Cyclodextrin Chem. Pharm. Bull. 73,pp.39-45 (Co-authored)
2.	2023	Papers	Zero-waste preparation of supramolecular hydrogels and films comprising tannic acid and ultra-high-molecular-weight polyethylene oxide Results in Materials 19,pp.100425 (Co-authored)
3.	2020	Papers	A Thermoresponsive Hydrophobically Modified Hydroxypropylmethyl Cellulose/Cyclodextrin Injectable Hydrogel for the Sustained Release of Drugs Int. J. Pharm. 575,,pp.118845 (Co-authored)
4.	2019	Papers	Physiologically Stable Hydrophilic C60 Nanoparticles for Photodynamic Therapy ACS Appl. Nano. Mater. 2,pp.716-725 (Co-authored)
5.	2008	Papers	Improved Stability of OPALMON Tablets under Humid Conditions IV:Effect of Polysaccharides and Disintegrants on the Stability and Dissolution Properties of OPALMON Tablets Chem. Pharm. Bull. 56,pp.7-11 (Co-authored)
6.	2008	Papers	Preparation of Amorphous Indomethacin from Aqueous 2,6-Di-O-methyl-β-cyclodextrin Solution Int. J. Pharm. 354,pp.70-76 (Co-authored)
7.	2008	Papers	Prominent Inhibitory Effect of 2-Hydroxybutyl-β-cyclodextrins on Solution-mediated Polymorphic Transition of Chlorpropamide Chem. Lett. 37,pp.816-817 (Co-authored)
8.	2009	Papers	Preparation of Hydrophilic Nanoparticles of C60 with High Resistance to Aggregation during Storage, Using 2-Hydroxypropyl-β-cyclodextrin Chem. Lett. 38,pp.1104-1105 (Co-authored)
9.	2010	Papers	Crystallization and Polymorphic Transition of Chlorpropamide in Aqueous 2-Hydroxybutyl-β-cyclodextrin Solution Eur. J. Pharm. Sci. 39,pp.248-255 (Co-authored)
10.	2010	Papers	Enhancement of the Aqueous Solubility and Masking the Bitter Taste of Famotidine Using Drug/SBE-β-CyD/Povidone K30 Complexation Approach J. Pharm. Sci. 99,pp.4285-4294 (Co-authored)
11.	2010	Papers	Evaluation of carboxymethyl-β-cyclodextrin with acid function: Improvement of chemical stability, oral bioavailability and bitter taste of famotidine Int. J. Pharm. 397,pp.1-8 (Co-authored)
12.	2011	Papers	Formation of Stable Hydrophilic C60 Nanoparticles by 2-Hydroxypropyl-β-cyclodextrin Mol. Pharmaceutics 8,pp.1276-1284 (Co-authored)
13.	2011	Papers	Reduction of Bitterness of Antihistaminic Drugs by Complexation with β-Cyclodextrins J. Pharm. Sci. 100,pp.1935-1943 (Co-authored)
14.	2011	Papers	Some pharmaceutical and inclusion properties of 2-hydroxybutyl-β-cyclodextrin derivative Int. J. Pharm. 419,pp.161-169 (Co-authored)
15.	2012	Papers	Antioxidant and Renoprotective Activity of Chitosan in Nephrectomized Rats Carbohydr. Polym. 89,pp.302-304 (Co-authored)
16.	2012	Papers	Cyclodextrin-induced Change in Crystal Habit of Acetylsalicylic Acid in Aqueous Solution Cryst. Growth Des. 12,pp.1985-1991 (Co-authored)
17.	2012	Papers	Evaluation of photodynamic activity of C60/2-hydroxypropyl-β-cyclodextrin nanoparticles J. Pharm. Sci. 101,pp.3390-3397 (Co-authored)
18.	2013	Papers	Crystallization of A New Polymorph of Acetohexamide from 2-Hydroxybutyl-β-cyclodextrin Solution: Form VI with A High Aqueous Solubility Int. J. Pharm., 453,pp.315-321 (Co-authored)
19.	2013	Papers	Preparation of soluble stable C60/human serum albumin nanoparticles via cyclodextrin complexation and their reactive oxygen production characteristics Life Sci., 93,pp.277-282 (Co-authored)
20.	2014	Papers	Combined Use of Cyclodextrins and Hydroxypropylmethylcellulose Stearoxy Ether (Sangelose) for the Preparation of Orally Disintegrating Tablets of Type-2 Antidiabetes Agent Glimepiride J. Inclusion Phenom. Macrocyclic Chem. 80,pp.61-67 (Co-authored)
21.	2014	Papers	Effects of chitosan on oxidative stress and related factors in hemodialysis patients Carbohyd. Polym. (Co-authored)
22.	2014	Papers	N-acetyl-L-methionine is a superior protectant of human serum albumin against photo-oxidation and reactive oxygen species compared to N-acetyl-L-tryptophan BBA-General Subjects 1840,pp.2806-2812 (Co-authored)
23.	2014	Papers	Potential Use of C60/2-Hydroxypropyl-β-cyclodextrin Nanoparticles as a New Photosensitizer in the Treatment of Cancer Int. J. Photoenergy. Article ID 570506 (Co-authored)
24.	2014	Papers	Preparation and antioxidant activity of PEGylated chitosans with different particle sizes Int. J. Biol. Macromol. 70,pp.64-69 (Co-authored)
25.	2014	Papers	Stabilizing Effect of β-Cyclodextrin on Limaprost, a PGE1 Derivative, in Limaprost Alfadex Tablets (Opalmon) in Highly Humid Conditions Chem. Pharm. Bull. 62,pp.786-792 (Co-authored)
26.	2015	Papers	Formation of Elastic Gels from Surface-deacetylated Chitin Nanofibers Reinforced with Sulfobutyl Ether β-Cyclodextrin Chem. Lett. 44,pp.285-287 (Co-authored)
27.	2015	Papers	Formation of Ternary Inclusion Complex of Limaprost with α- and β-Cyclodextrins in Aqueous Solution Chem. Phram. Bull. 63,pp.318-325 (Co-authored)
28.	2015	Papers	Preparation of Hydrophilic C60(OH)10/2-Hydroxypropyl-β-cyclodextrin Nanoparticles for the Treatment of a Liver Injury Induced by an Overdose of Acetaminophen Biomaterials (Co-authored)
29.	2015	Papers	Slow-release of famotidine from tablets consisting of chitosan/sulfobutyl ether β-cyclodextrin composites Int. J. Pharm. 487,pp.142-147 (Co-authored)
30.	2015	Papers	Surface-deacetylated Chitin Nano-fiber/hyaluronic Acid Composites as Potential Antioxidative Compounds for Use in Extended-release Matrix Tablets Int. J. Mol. Sci. (Co-authored)
31.	2016	Papers	Antioxidant and renoprotective activity of 2-hydroxypropyl- β-cyclodextrin in nephrectomized rats J. Pharm. Pharmacol. (Co-authored)
32.	2016	Papers	Biomaterials based on freeze dried surface-deacetylated chitin nanofibers reinforced with sulfobutyl ether β-cyclodextrin gel in wound dressing applications Int. J. Pharm., 511, 1080-1087 (2016). (Co-authored)
33.	2016	Papers	In vitro and In vivo Evaluation of Hydrophilic C60OH10/2-Hydroxypropyl-β-cyclodextrin Nanoparticles as an Antioxidant J. Pharm. Sci., 105, 2959-2965 (2016). (Co-authored)
34.	2016	Papers	N-acetyl-L-methionine is a superior protectant of human serum albumin against post-translational oxidation as compared to N-acetyl-L-tryptophan Biochem. Biophys. Rep., 6, 266-274 (2016). (Co-authored)
35.	2016	Papers	Ternary Inclusion Complex Formation and Stabilization of Limaprost, A Prostaglandin E1 Derivative, in the Presence of α- and β-cyclodextrins in the solid state Int. J. Pharm., 509, 338-347 (2016). (Co-authored)
36.	2016	Papers	The formation of an inclusion complex between a metabolite of ginsenoside, compound K, and γ-cyclodextrin and its dissolution characteristics J. Pharm. Pharmacol. (Co-authored)
37.	2016	Papers	Thermoresponsive Formation of Dimethyl Cyclodextrin Polypseudorotaxanes and Subsequent One-Pot Synthesis of Polyrotaxanes ACS Macro Lett., 5, 158-162 (2016). (Co-authored)
38.	2017	Papers	A Comparison of the Phosphorus Content in Prescription Medications for Hemodialysis Patients in Japan YAKUGAKU ZASSHI, 137, 903-908 (2017). (Co-authored)
39.	2017	Papers	An oral absorbent, surface-deacetylated chitin nano-fiber ameliorates renal injury and oxidative stress in 5/6 nephrectomized rats Carbohyd. Polym.,161, 21-25 (2017). (Co-authored)
40.	2017	Papers	Hydrophobically Modified Polymer/α-Cyclodextrin Thermoresponsive Hydrogels for Use in Ocular Drug Delivery Mol. Pharmaceutics, 14, 2740-2748 (2017). (Co-authored)
41.	2017	Papers	Surface-deacetylated chitin nanofibers reinforced with a sulfobutyl ether β-cyclodextrin gel loaded with prednisolone as potential therapy for inflammatory bowel disease Carbohyd. Polym., 174, 1087-1094 (2017). (Co-authored)
42.	2018	Papers	Antioxidant activities of chitosans and its derivatives in in vitro and in vivo studies Carbohyd. Polym. 199,pp.141-149 (Co-authored)
43.	2018	Papers	Glucose Responsive Rheological Change and Drug Release from a Novel Worm-like Micelle Gel Formed in Cetyltrimethylammonium Bromide/Phenylboronic Acid/Water System Mol. Pharmaceutics, 15, 1097-1104 (2018). (Co-authored)
44.	2018	Papers	Release control of fragrances by complexation with β-cyclodextrin and its derivatives, J. Incl. Phenom. Macrocycl. Chem. 92,pp.147-155 (Co-authored)
45.	2018	Papers	Sacran, a High-molecular Weight Polysaccharide Inhibits Renal Injury and Oxidative Stress in Chronic Renal Failure Model Rats J. Nutri. Bio. 4,pp.267-275 (Co-authored)
46.	2018	Papers	Supramolecular Pharmaceutical Sciences: A Novel Concept Combining Pharmaceutical Sciences and Supramolecular Chemistry with Focus on Cyclodextrin-based Supermolecules Chem. Pharm. Bull., 66, 207-216 (2018). (Co-authored)
47.	2018	Papers	Synthesis, Aggregation Behavior, and Photodynamic Properties of a Water-Soluble Fulleropyrrolidine Bearing an N-PEG Pyridinium Unit Chem. Pharm. Bull. 66,pp.822-825 (Co-authored)
48.	2019	Papers	Design and Evaluation of An Extended-Release Olmesartan Tablet Using Chitosan/Cyclodextrin Composites Pharmaceutics 11 (82) (Co-authored)
49.	2019	Papers	In vitro and in vivo evaluation of 6-O-α-maltosyl-β-cyclodextrin as a potential therapeutic agent against Niemann-Pick disease Type C Int. J. Mol. Sci. 20,pp.1152 (Co-authored)
50.	2019	Papers	Modification of Drug Crystallization by Cyclodextrins in Pre-Formulation Study Chem. Pharm. Bull. 67,pp.915-920 (Co-authored)
51.	2019	Papers	Preparation and evaluation of freeze dried surface-deacetylated chitin nanofiber/sacran pellets for use as an extended-release excipient Int. J. Biol. Macromol. 124,pp.888-894 (Co-authored)
52.	2019	Papers	The Use of Enteric Capsules for Releasing a Fragrance over an Extended Period of Time Chem. Pharm. Bull. (Co-authored)
53.	2020	Papers	Effects of surface-deacetylated chitin nanofibers on non-alcoholic steatohepatitis model rats and their gut microbiota Int. J. Biol. Macromol. 164,pp.659-666 (Co-authored)
54.	2020	Papers	In vitro transdermal permeation of isosorbide dinitrate in the absence and presence of 2-hydroxypropyl-β-cyclodextrin:solutions and suspensions J. Incl. Phenom. Macrocycl. Chem. 96,pp.137-143 (Co-authored)
55.	2020	Papers	Morphometric analysis of paramylon particles produced by Euglena gracilis EOD-1 using FIB/SEM tomography Chem. Pharm. Bull. 68,pp.100-102 (Co-authored)
56.	2020	Papers	Polypseudorotaxane-based supramolecular hydrogels consisting of cyclodextrins and Pluronics as stabilizing agents for antibody drugs Carbohyd. Polym. 256,pp.117419 (Co-authored)
57.	2020	Papers	Processing grapefruit juice with γ-cyclodextrin attenuates its inhibitory effect on cytochrome P450 3A activity J. Pharm. Pharmacol. 72,pp.356-363 (Co-authored)
58.	2020	Papers	The preparation and validation of chitosan tablets that rapidly disperse and disintegrate as an oral adsorbent in the treatment of lifestyle-related diseases Carbohyd. Polym. 253,pp.117246 (Co-authored)
59.	2021	Papers	Sacran, a sulfated polysaccharide, suppresses the absorption of lipids and modulates the intestinal flora in non-alcoholic steatohepatitis model rats Life Sci. 5,pp.118991 (Co-authored)
60.	2021	Papers	Supramolecular Assembly of Hybrid Pt(II) Porphyrin/Tomatine Analogues with Different Nanostructures and Cytotoxic Activities ACS Omega 6,pp.13284-13292 (Co-authored)
61.	2022	Papers	Study of the Inclusion Complexes Formed Between 4-Phenylbutyrate and α-, β-, and γ-Cyclodextrin in Solution and Evaluation on Their Taste-Masking Properties J. Pharm. Pharmacol 75 (2),pp.236-244 (Co-authored)
62.	2022	Papers	Development of carbon nanoparticles for use in medical applications,pp.153-158 (Sole-authored)
63.	2023	Papers	Study of the Structural Chemistry of the Inclusion Complexation of 4-Phenylbutyrate and Related Compounds with Cyclodextrins in Solution: Differences in Inclusion Mode with Cavity Size Dependency Int. J. Mol. Sci. 24,pp.15091 (Co-authored)
64.	2023	Papers	Zero-waste preparation of supramolecular hydrogels and films comprising tannic acid and ultra-high-molecular-weight polyethylene oxide Results in Materials 19,pp.100425 (Co-authored)
65.	2024	Papers	Development of α-Cyclodextrin-Based Orally Disintegrating Tablets for 4-Phenylbutyrate Pharmaceutics 16,pp.82 (Co-authored)
66.	2024	Papers	Effect of Acetaminophen on Poloxamer 407 Micelles and Hydrogels: The Relationship between Structural and Physical Properties Langmuir 40,pp.15610-15620 (Co-authored)