Faculty Information - Nakamura Hideaki

Nakamura Hideaki

Department / Course FACULTY OF PHARMACEUTICAL SCIENCES Department of Pharmaceutical Sciences

Job

Book and thesis
1.	2023/02	Papers	The G protein-coupled receptor ligand apelin-13 ameliorates skeletal muscle atrophy induced by chronic kidney disease. Journal of cachexia, sarcopenia and muscle 14 (1),pp.553-564 (Co-authored)
2.	2022/12	Papers	Recent topics and advanced therapies in chronic granulomatous disease. Human cell (Co-authored)
3.	2022/08	Papers	Treatment with Polyethylene Glycol-Conjugated Fungal D-Amino Acid Oxidase Reduces Lung Inflammation in a Mouse Model of Chronic Granulomatous Disease. Inflammation 45 (4),pp.1668-1679 (Co-authored)
4.	2021/05	Papers	De novo filament formation by human hair keratins K85 and K35 follows a filament development pattern distinct from cytokeratin filament networks. FEBS Open Bio 11 (5),pp.1299-1312 (Co-authored)
5.	2021/09	Papers	Acid-responsive HPMA copolymer-bradykinin conjugate enhances tumor-targeted delivery of nanomedicine J Control Release 337,pp.546-556 (Co-authored)
6.	2021/01	Papers	Preparation of enzymatically highly active pegylated-D-amino acid oxidase and its application to antitumor therapy. Curr Drug Deliv (Co-authored)
7.	2020/05	Papers	Efficient Anticancer Drug Delivery for Pancreatic Cancer Treatment Utilizing Supramolecular Polyethylene-Glycosylated Bromelain ACS Applied Bio Materials 3 (5),pp.3005-3014 (Co-authored)
8.	2020/04	Papers	Highly effective anti-tumor nanomedicines based on HPMA copolymer conjugates with pirarubicin prepared by controlled RAFT polymerization. Acta Biomater 106,pp.256-266 (Co-authored)
9.	2019/07	Papers	Superior Penetration and Cytotoxicity of HPMA Copolymer Conjugates of Pirarubicin in Tumor Cell Spheroid. Molecular Pharmaceutics (Co-authored)
10.	2019/05	Papers	In vivo Efficacy and Safety Evaluation of Lactosyl-β-cyclodextrin as a Therapeutic Agent for Hepatomegaly in Niemann-Pick Type C Disease. Nanomaterials 9 (5) (Co-authored)
11.	2018/05	Papers	The role of vimentin in the tumor marker Nup88-dependent multinucleated phenotype. 18 (1),pp.519 (Co-authored)
12.	2018	Papers	Preparation and in Vitro Analysis of Human Serum Albumin Nanoparticles Loaded with Anthracycline Derivatives. Chem Pharm Bull (Tokyo). 66 (4),pp.382-390 (Co-authored)
13.	2017/10	Papers	Comparison of the pharmacological and biological properties of HPMA copolymer-pirarubicin conjugates: A single-chain copolymer conjugate and its biodegradable tandem-diblock copolymer conjugate. Eur J Pharm Sci. 106,pp.10-19 (Co-authored)
14.	2017/09	Papers	Improved anticancer effects of albumin-bound paclitaxel nanoparticle via augmentation of EPR effect and albumin-protein interactions using S-nitrosated human serum albumin dimer. Biomaterials. 140,pp.162-169 (Co-authored)
15.	2017/04	Papers	Hyaluronic Acid-zinc Protoporphyrin IX Conjugates for Photodynamic Antitumor Therapy Journal of Nanomedicine & Nanotechnology (Co-authored)
16.	2016/12	Papers	Pronounced Cellular Uptake of Pirarubicin versus That of Other Anthracyclines: Comparison of HPMA Copolymer Conjugates of Pirarubicin and Doxorubicin. Mol Pharm. 13 (12),pp.4106-4115 (Co-authored)
17.	2016/05	Papers	Missile-Type Tumor-Targeting Polymer Drug, P-THP, Seeks Tumors via Three Different Steps Based on the EPR Effect,pp.549-557 (Co-authored)
18.	2016/04	Papers	N-acetyl-L-methionine is a superior protectant of human serum albumin against post-translational oxidation as compared to N-acetyl-L-tryptophan. Biochem Biophys Rep. 6,pp.266-274 (Co-authored)
19.	2016/02	Papers	pH-sensitive polymeric cisplatin-ion complex with styrene-maleic acid copolymer exhibits tumor-selective drug delivery and antitumor activity as a result of the enhanced permeability and retention effect Colloids Surf B Biointerfaces 138,pp.128-137 (Co-authored)
20.	2015	Papers	HPMA Copolymer-Conjugated Pirarubicin in Multimodal Treatment of a Patient with Stage IV Prostate Cancer and Extensive Lung and Bone Metastases. Target Oncol (Co-authored)
21.	2015/08	Papers	S-Nitrosated human serum albumin dimer as novel nano-EPR enhancer applied to macromolecular anti-tumor drugs such as micelles and liposomes. J Control Release 217,pp.1-9 (Co-authored)
22.	2015/03	Papers	Synthesis and therapeutic effect of styrene-maleic acid copolymer-conjugated pirarubicin. Cancer Sci 106 (3),pp.270-278 (Co-authored)
23.	2015/02	Papers	Comparison between linear and star-like HPMA conjugated pirarubicin (THP) in pharmacokinetics and antitumor activity in tumor bearing mice. Eur J Pharm Biopharm 90,pp.90-96 (Co-authored)
24.	2015/01	Papers	Development of next-generation macromolecular drugs based on the EPR effect: challenges and pitfalls. Expert Opin Drug Deliv 12 (1),pp.53-64 (Co-authored)
25.	2015/03	Papers	Photodynamic therapy and imaging based on tumor-targeted nanoprobe, polymer-conjugated zinc protoporphyrin Future Science OA (Co-authored)
26.	2015/01	Papers	Effect of different chemical bonds in pegylation of zinc protoporphyrin that affects drug release, intracellular uptake, and therapeutic effect in the tumor Eur J Pharm Biopharm 89,pp.259-270 (Co-authored)
27.	2014/10	Papers	Enhanced bacterial tumor delivery by modulating the EPR effect and therapeutic potential of Lactobacillus casei J Pharm Sci 103 (10),pp.3235-3243 (Co-authored)
28.	2014/08	Papers	Styrene-maleic acid copolymer-encapsulated CORM2, a water-soluble carbon monoxide (CO) donor with a constant CO-releasing property, exhibits therapeutic potential for inflammatory bowel disease. J Control Release 187,pp.14-21 (Co-authored)
29.	2014/01	Papers	Two step mechanisms of tumor selective delivery of N-(2-hydroxypropyl)methacrylamide copolymer conjugated with pirarubicin via an acid-cleavable linkage. J Control Release 174,pp.81-87 (Co-authored)
30.	2013/12	Papers	Protection from inflammatory bowel disease and colitis-associated carcinogenesis with 4-vinyl-2,6-dimethoxyphenol (canolol) involve suppression of oxidative stress and inflammatory cytokines. Carcinogenesis 34,pp.2833-2841 (Co-authored)
31.	2013	Papers	Characterization of Carotenoid Fatty Acid Esters from the Peels of the Persimmon Diospyros kaki Chem Pharm Bull (Tokyo) 61,pp.666-669 (Co-authored)
32.	2013	Books	Cancer Chemotherapy Fundamentals of Pharmaceutical Nanoscience,pp.401-427 (Co-authored)
33.	2012	Papers	Protective Role of D -Amino Acid Oxidase Against Staphylococcus aureus Infection. Infect Immun 80,pp.1546-1553 (Co-authored)
34.	2012	Papers	Pegylated D -amino acid oxidase restores bactericidal activity of neutrophils in chronic granulomatous disease via hypochlorite Exp Biol Med 237,pp.703-708 (Co-authored)
35.	2012	Papers	HSP32 (HO-1) inhibitor, copoly(styrene-maleic acid)-zinc protoporphyrin IX, a water-soluble micelle as anticancer agent: In vitro and in vivo anticancer effect. Eur. J. Pharm. Biopharm 81,pp.540-547 (Co-authored)
36.	2012	Papers	Carbon monoxide, generated by heme oxygenase-1, mediates the enhanced permeability and retention effect in solid tumors Cancer Sci 103,pp.535-541 (Co-authored)
37.	2011	Papers	Therapeutic potential of pegylated hemin for reactive oxygen species-related diseases via induction of heme oxygenase-1: results from a rat hepatic ischemia/reperfusion injury model. J Pharmacol Exp Ther 339,pp.779-789 (Co-authored)
38.	2011	Papers	The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect Adv Drug Deliv Rev 63,pp.136-151 (Co-authored)
39.	2011	Papers	Intracellular uptake and behavior of two types zinc protoporphyrin (ZnPP) micelles, SMA-ZnPP and PEG-ZnPP as anticancer agents; unique intracellular disintegration of SMA micelles. J Control Release 155,pp.367-375 (Co-authored)
40.	2011	Papers	4-Amino-6-hydroxypyrazolo [3,4-d]pyrimidine (AHPP) conjugated PEG micelles : water soluble polymeric xanthine oxidase inhibitor. J Drug Target 19,pp.954-966 (Co-authored)
41.	2009	Papers	SMA-copolymer conjugate of AHPP: a polymeric inhibitor of xanthine oxidase with potential antihypertensive effect. J Control Release 135,pp.211-217 (Co-authored)
42.	2008	Papers	Targeting of heat shock protein 32 (Hsp32)/heme oxygenase-1 (HO-1) in leukemic cells in chronic myeloid leukemia: a novel approach to overcome resistance against imatinib. Blood 111,pp.2200-2210 (Co-authored)
43.	2008	Papers	Oxystress inducing antitumor therapeutics via tumor-targeted delivery of PEG-conjugated D-amino acid oxidase. Int J Cancer 122,pp.1135-1144 (Co-authored)
44.	2007	Papers	Tumor-targeted induction of oxystress for cancer therapy. J Drug Target 15,pp.475-486 (Co-authored)
45.	2006	Papers	SUMO down-regulates the activity of Elf4/myeloid Elf-1-like factor. Biochem Biophys Res Commun 348,pp.880-888 (Co-authored)
46.	2005	Papers	Sp1-dependent regulation of Myeloid Elf-1 like factor in human epithelial cells. FEBS Lett 579,pp.2811-2816 (Co-authored)