教員情報 - 山口　幸輝

ヤマグチ　コウキ Yamaguchi Kouki
山口　幸輝

所属薬学部薬学科

職種教授

著書・論文歴
1.	2023	論文	Study of the Structural Chemistry of the Inclusion Complexation of 4-Phenylbutyrate and Related Compounds with Cyclodextrins in Solution: Differences in Inclusion Mode with Cavity Size Dependency Int. J. Mol. Sci. 24 (20),15091 (共著)
2.	2023	論文	Recruitment of Hexahydroquinoline as Anticancer Scaffold Targeting Inhibition of Wild and Mutants EGFR (EGFR^WT, EGFR^T790M, and EGFR^L858R) J Enzyme Inhib Med Chem 38 (1),2241674 (共著)
3.	2023	論文	Organic Base-Catalyzed Cascade Reaction of Electron-Deficient Cyclopentadienone with Prop-2-yn-1-ols: Formation of 3-Methylenetetrahydrofuran Ring Condensed with Cyclopentenone Heterocycles 106 (3),465-478頁 (単著)
4.	2023	論文	Study of the Inclusion Complexes Formed Between 4-Phenylbutyrate and α-, β-, and γ-Cyclodextrin in Solution and Evaluation on Their Taste-Masking Properties J Pharm Pharmacol 75 (2),236-244頁 (共著)
5.	2022	論文	Synthesis, crystallographic, DNA binding, and molecular docking/dynamic studies of a privileged chalcone-sulfonamide hybrid scaffold as a promising anticancer agent JOURNAL OF BIOMOLECULAR STRUCTURE AND DYNAMICS (共著)
6.	2021	論文	STEPWISE REACTIONS BETWEEN CYCLIC 1,4-DIAZADIENES AND KETENES: CHARACTERISTICS AND MECHANISM Heterocycles 102 (3),534-545頁 (共著)
7.	2020	論文	Reactivity of the Enamine Tautomer of a Cyclic 1,4-Diazadiene with a Diketone Heterocycles 100 (9),1463-1472頁 (共著)
8.	2020	論文	平成30年度ベストティーチング賞受賞教員の授業について―更なる授業改善を目指して（第3報）― 崇城大学紀要 45,97-110頁 (共著)
9.	2019	論文	Lewis Base-Catalyzed Enantioselective Conjugate Reduction of β,β-Disubstituted α,β-Unsaturated Ketones with Trichlorosilane: E/Z-Isomerization, Regioselectivity, and Synthetic Applications. [Highlighted in Organic Chemistry Portal; Featured in Org. Chem. Highlights: Alkylated Stereogenic Centers] The Journal of Organic Chemistry 84 (18),11458-11473頁 (共著)
10.	2019	論文	Selective Monoacylation of Diols and Asymmetric Desymmetrization of Dialkyl meso-Tartrates Using 2-Pyridyl Esters as Acylating Agents and Metal Carboxylates as Catalysts The Journal of Organic Chemistry 84 (14),9313-9321頁 (共著)
11.	2019	論文	Reaction of 2,3,5,6,7,8-Hexahydroquinoxaline with Thiourea Derivatives: Analysis of the Structure and Conformational State of [4.4.3]Propellane Heterocycles 98 (1),88-95頁 (共著)
12.	2017	論文	N-HETEROCYCLIC CARBENE-PROMOTED [3+2] CYCLOADDITION OF ALLENYL SULFONE AND ARYLIDENEMALONONITRILES HETEROCYCLES 95 (1),232-242頁 (共著)
13.	2015	論文	Cyclic Sulfoxides-Garlicnins K1, K2, and H1-Extracted from Allium sativum Chem. Pharm. Bull 63 (2),117-121頁 (共著)
14.	2014	論文	Acyclic Sulfides, Garlicnins L-1-L-4, E, and F, from Allium sativum Chem. Pharm. Bull. 62 (5),477-482頁 (共著)
15.	2014	論文	Isolable Atropisomers of 2-Aryl Indoline Derivatives: Determination of Rotational Barrier by Density Functional Theory Approach Tetrahedron 70 (9),1811-1817 (共著)
16.	2014	論文	Isolation and Characterization of New Onionins A2 and A3 from Allium cepa, and of Onionins A1, A2, and A3 from Allium fistulosum Chem. Pharm. Bull. 62 (11),1141-1145頁 (共著)
17.	2013	論文	A new diterpenoid from the leaves of Clerodendron trichotomum J. Nat. Med. 67,404-409 (共著)
18.	2013	論文	Formation Mechanism of Triketo Cage Compounds from Reaction of Phencyclone with Benzoquinones: Cascade Reaction of Intermolecular [4+2]π and Intramolecular [2+2]π Cycloadditions Chem. Pharm. Bull. 61 (10),1065-1070 (共著)
19.	2013	論文	Role of CH/O and CH/P interactions in structural stability. Effect on endo selectivity in 1,3-dipolar reaction of electron-deficient 4-Oxo-4H-pyrazole 1,2-dioxides with N-substituted maleimides Heterocycles 87 (2),319-328 (共著)
20.	2013	論文	Thermal Reaction of Electron Deficient 4-Oxo-4H-pyrazole 1,2-Dioxide with Cycloheptatriene: The First Examples of the Formation of an Endo-[4π+6π]-cycloadduct and an Intramolecular 1,3-Dipolar Reaction Leading to a Heterocage J. Phys. Org. Chem. 26,64-69 (共著)
21.	2012	論文	Clathrate formation of DielseAlder adduct of phencyclone and acenaphthylene. Key role of CH/p and bidentate CH/O interactions of the phenanthrene ring in construction of host framework Tetrahedron 68,3566-3576 (共著)
22.	2012	論文	Cyclodextrin-Induced Change in Crystal Habit of Acetylsalicylic Acid in Aqueous Solution Cryst. Growth Des 12,1985-1991 (共著)
23.	2011	論文	DABCO-Triggered mild cascade reaction of electron-deficient cyclopentadienone: facile and efficient synthesis of condensed carbocycles Tetrahedron Lett. 52 (46),6082-6085 (共著)
24.	2011	論文	Formation Mechanism of Furfuryl Sulfides from O-Furfuryl Dithiocarbonates: Density Functional Theory Study for Aromatic [3,3]-Sigmatropic Rearrangement Chem. Pharm. Bull. 59 (6),681-685 (共著)
25.	2011	論文	Role of edge-to-face interaction between aromatic rings in clathrate formation of 1-benzoyl -2-hydroxyindoline derivatives with benzene. X-ray crystal and PM6 analyses of the interaction Tetrahedron 67 (38),7400-7405 (共著)
26.	2010	論文	Conformation of aromatic rings in isolable atropisomers of 2-arylindoline derivatives and kinetic evidences for π-π interaction Tetrahedron 66,898-903 (共著)
27.	2010	論文	New Formation Mechanism of Allylic Trithiocarbonates from Sodium O-(2-Alkenyl) Dithiocarbonates via Sequential Pericyclic Reactions: Density Functional Theory Study Chem. Pharm. Bull. 58,1517-1520 (共著)
28.	2009	論文	Chemical Reactivity of Dihydrohyrazine Derivatives. Cylcoaddition Behavior toward Ketenes. Chem. Pharm. Bull. 57 (4),846-852 (共著)
29.	2009	論文	Crystallographic Evidence for Cyclopropane Ring Formation in Isotwistenes Obtained by Thermal Cascade Reactions of Cyclopentadienone with Acyclic Conjugated Dienes. Chem. Pharm. Bull. 57 (7),749-751 (共著)
30.	2009	論文	Formation pathway of novel cycloadduct obtained by reaction of 3,5-disubstituted 4-oxo-4H-pyrazole 1,2-dioxide with dimethyl acetylenedicarboxylate. Heterocycles 78 (11),2777-2785 (共著)
31.	2009	論文	Role of 2-Naphthyl Ether Intermediate in Formation of Isolable Atropisomers Derived from the Coupling Reaction of (2-Hydroxy-3,3-dimethylindolin-1-yl) (Substituted phenyl) methanones with 2-Naphthol. Heterocycles 78 (6),1485-1496 (共著)
32.	2009	論文	Tetraazaindenes derived from dihydropyrazines with DNA strand-breaking activity Chem. Pharm. Bull. 57 (12),1371-1375 (共著)
33.	2008	論文	A new homostilbene and two new homoisoflavones from the bulbs of Scilla scilloides. Chem. Pharm. Bull. 56 (7),1022-1025 (共著)
34.	2008	論文	New C(28) steroidal glycosides from Tubocapsicum anomalum. Chem. Pharm. Bull. 56 (7),1038-1040 (共著)
35.	2007	論文	New C_28 Steroidal Glycosides from /Tubocapsicum anomalum/ Chem. Pharm. Bull. 55 (1),34-36 (共著)
36.	2007	論文	Reaction of 1-acyl and aroyl-2-hydroxy-3,3-dimethylindoline with arylamines catalyzed by bf3-etherate. formation of 12,12a-dihydroindolo[1,2-c]quinazoline Heterocycle 71 (2),343-359 (共著)
37.	2006	論文	Cyclization reaction of cyclopentadienone with prop-2-yn-1-ol in priority to Diels-Alder reaction Tetrahedron Lett. 47 (25),4235-4239 (共著)
38.	2005	論文	A Novel clathrate host allowing structural adjustment during the inclusion of 1,2-diaminoethanes Tetrahedron Lett. 46 (7),1087-1090 (共著)
39.	2004	論文	Another Aspect of the Reaction Behavior of Cyclopentadienones. 1,5-Sigmatropic Rearrangement of the 1,4-Addition Products of Amines Eur. J. Org. Chem. 2004 (4),826-834 (共著)
40.	2001	論文	Cyclization of Electron-Deficient Cyclopentadienone with 2-Alkenyl and 2-Alkynylamines via Sequential Pericyclic Reaction Pathway J. Org. Chem. 66 (26),8902-8911 (共著)