教員情報 - 横溝　和美

ヨコミゾ　カズミ Yokomizo Kazumi
横溝　和美

所属薬学部薬学科

職種教授

著書・論文歴
1.	2025/10/30	論文	Bioactivity of pyridine and isoquinoline homodimers Tetrahedron Letters 170,155756 (共著)
2.	2025/08/28	論文	Differentiation-inducing factor-1 inhibits dendritic cell function by attenuating toll-like receptor 4 and phospho-nuclear factor-κB signaling in vitro International Immunopharmacology 161,114961 (共著)
3.	2025/05/21	論文	Nano-drug delivery system of natural products for disease prevention and treatment. Expert Opin Drug Deliv. (共著)
4.	2025/05/13	論文	Eight new resin glycosides, calyhedins XXIV–XXXI, from the rhizomes of Calystegia hederacea Journal of Natural Medicines (共著)
5.	2024/05/28	論文	Saponin Esculeside A and aglycon Esculeogenin A from ripe tomatoes inhibit dendritic cell function by attenuation of toll-like receptor 4 signaling. Nutrients 16 (11),1699 (共著)
6.	2024/03/08	論文	Four new resin glycosides from Ipomoea muricata seeds: muricatins XIV–XVII Journal of Natural Medicines (共著)
7.	2023/09/04	論文	Extract essence of seven Chinese herbs potentially exhibit anti-inflammatory and cancer-preventive effects. Food Materials Research 3 (19) (共著)
8.	2023/04/03	論文	Garlicnin B1, an Active Cyclic Sulfide from Garlic, Exhibits Potent Anti-Inflammatory and Anti-Tumor Activities. Antioxidants 12 (4),868-880頁 (共著)
9.	2023/01	論文	HPMA copolymer conjugated 5-aminolevulinic acid exhibits superior efficacy for photodynamic therapy with tumor-responsive and targeting properties. Nanomedicine 48,102636 (共著)
10.	2022/08	論文	Antiviral activity of some C3-symmetrical N-methyl benzylamine-substituted 1,3,5-triazines and related compounds Heterocycles 104 (10) (共著)
11.	2022/05	論文	Ripe Tomato Saponin Esculeoside A and Sapogenol Esculeogenin A Suppress CD4+ T Lymphocyte Activation by Modulation of Th2/Th1/Treg Differentiation. Nutrients 14 (10),2021 (共著)
12.	2022/04	論文	Tumor Stimulus-Responsive Biodegradable Diblock Copolymer Conjugates as Efficient Anti-Cancer Nanomedicines Journal of personalized medicine 12 (5),698 (共著)
13.	2022/04	論文	Decrease of Hyaluronidase Activity and Suppression of Mouse CD4+ T Lymphocyte Activation by Tomato Juice Saponin Esculeoside B, and Its Sapogenol Esculeogenin B J. Pers. Med. 12,579 (共著)
14.	2022/03	論文	Different effects on the tonus of colon and ileum isolated from mouse by resin glycoside (pharbitin) of Pharbitidis Semen. BMC Complementary Medicine and Therapies 22,82 (共著)
15.	2022/01	論文	Bioactivity of boronic acid derivative homodimers Results in Chemistry 4,10055 (単著)
16.	2021/12	論文	Expression Dynamics of Heme Oxygenase-1 in Tumor Cells and the Host Contributes to the Progression of Tumors 11 (12),1340 (共著)
17.	2021/10	論文	Styrene Maleic Acid Copolymer-Based Micellar Formation of Temoporfin (SMA@ mTHPC) Behaves as A Nanoprobe for Tumor-Targeted Photodynamic Therapy with A Superior Safety 9,1493 (共著)
18.	2021/10	論文	HYBRID LINKER MODE C2-SYMMETRICAL 1,3,5-TRIAZINE DERIVATIVES AND THEIR BIOLOGICAL EVALUATION HETEROCYCLES 102 (12) (共著)
19.	2021/06	論文	Novel acyclic sulfide, garlicnin L-5, from garlic Current Topics in Phytochemistry (17),29-34頁 (共著)
20.	2021/06	論文	Determination of absolute configuration of the most abundant garlic sulfide, garlicnin B1 Current Topics in Phytochemistry (17),55-61頁 (共著)
21.	2021/05	論文	Unraveling the role of Intralipid in suppressing off-target delivery and augmenting the therapeutic effects of anticancer nanomedicines Acta Biomaterialia (共著)
22.	2020/12	論文	Novel bis-thiolane-type sulfide from garlic Current Topics in Phytochemistry (16),116-121頁 (共著)
23.	2020/04	論文	Some Hybrid Linker Mode C2-Symmetrical 1,3,5-Triazine Derivatives and Their Biological Evaluation HETEROCYCLES (共著)
24.	2019/11	論文	Anti-proliferative Activities of Some Bivalent Symmetrical 5-Substituted Hydantoin Derivatives Towards Human Brain Glioma U251 Cells (U251) and Human Carcinoma Cells (KB3-1) Biol Pharm Bull. 42 (11),1953-1956頁 (共著)
25.	2019/06	論文	漢方健康飲料による総合的美容効果皮膚と美容 51 (2),42-48頁 (共著)
26.	2019/04	論文	PREPARATION OF SOME NOVEL TRISUBSTITUTED 1,3,5-TRIAZINES AND HYBRID LINKER MODE 1,3,5-TRIAZINE DERIVATIVES AND THEIR BIOLOGICAL EVALUATION HETEROCYCLES 98 (4),489-508頁 (共著)
27.	2019	論文	Anti-proliferative Activities towards Human Brain Glioma U251 Cells and Human Carcinoma Cells (KB3-1) of Some Twin-Drug Type Bivalent C₂-Symmetrical Phenylboronic Acid Derivatives. Biological & pharmaceutical bulletin 42 (5),830-838頁 (共著)
28.	2018/09	論文	Novel C₂-Symmetrical Phenylboronic Acid Pinacol Esters with a Few Types of Linkers and Their Biological Activities. Heterocycles (共著)
29.	2018/06	論文	Carbohydrate recognition of C₃-symmetrical tripodal receptor-type 2,4,6-trisubstituted 1,3,5-triazine derivatives with antiviral activities. Journal of Thermal Analysis and Calorimetry 135 (5) (共著)
30.	2018/03	論文	Hyaluronic Acid-zinc Protoporphyrin IX Conjugates for Photodynamic Antitumor Therapy. (共著)
31.	2018/01	論文	Preparation and Biological Activity of Novel Twin-drug Type C₂-Symmetrical Cyclic Phenylboronic Acid Derivatives. Heterocycles (共著)
32.	2002/06	論文	Recent Research Developments in Antibiotics Transworld Research Network Vol.1,35-53 (共著)
33.	2007	論文	A broad anti-viral neutral glycolipid, fattiviracin FV-8,is a membrane fluidity modulator. Cell. Microbiol. 9,196-203 (共著)
34.	2007	論文	N-long-chain monoacylated derivatives of 2,6-diaminopyridine with antiviral activity. Chem. Pharm. Bull. 55,111-114 (共著)
35.	2007	論文	N-Monocarbamoyl Derivatives of Symmetrical Diamines with Antiviral Activity. Chem. Pharm. Bull. 55,1406-1411 (共著)
36.	2007	論文	伝統医薬品と健康補助食品の薬理未病と抗老化 16,36-41 (共著)
37.	2008	論文	Antiviral activities against herpes simplex virus type 1 by HPH derivatives and their structure-activity relationships. Bioorg. Med. Chem. Lett. 18,371-374 (共著)
38.	2008	論文	Glycyrrhizin inhibits interleukin-8 production and nuclear factor-kappaB activity in lung epithelial cells,but not through glucocorticoid receptors. J. Pharmacol.Sci. 106,460-468 (共著)
39.	2008	論文	Synthesis and antiviral activities of N-mono- and /or N,N ’-di-carbamoyl and acyl derivatives of symmetrical diamines. Chem. Pharm. Bull. 56,1052-1058 (共著)
40.	2008	論文	伝統医薬学教育・研究に求められるもの－グローバル保健医療の視点から－日本未病システム学会雑誌 14 (1),1-5 (共著)
41.	2009	論文	アガリクス培養物の老化マウス自発的掻破行動抑制作用と抗酸化作用について日本未病システム学会雑誌 15,292-295 (共著)
42.	2010	論文	Glycyrrhizin attenuates mucus production by inhibition of MUC5AC mRNA expression in vivo and in vitro. J. Pharmacol. Sci. 113,76-83 (共著)
43.	2010	論文	HSP70 inducers from Chinese herbs and their effect on melanin production.melanin production. Exp Dermatol. 19,340-342 (共著)
44.	2010	論文	Low direct cytotoxicity of loxoprofen on gastric mucosal cells. Biol Pharm Bull 33,398-403 (共著)
45.	2010	論文	Synthesis and Antiviral Activities of Some Heteroaryl-substituted Triarylmethanes J. Heterocycl.Chem 47,1434-1438 (共著)
46.	2011	論文	Identification and characterization of component organic and glycosidic acids of crude resin glycoside fraction from Calystegia soldanella. Chem. Pharm. Bull. 59,1163-1168 (共著)
47.	2011	論文	Synthesis and biological activities of some N-acyl-2,6-diaminopyridines and related linker mode identical twin drugs. Heterocycles 83,385-393 (共著)
48.	2011	論文	未病とくすり日本未病システム学会雑誌 17 (1),60-65 (共著)
49.	2012	論文	Ergogenic Capacity of a 7-Chinese Traditional Medicine Extract in Aged Mice Chiese Medicine (共著)
50.	2012	論文	Evaluation of safety and beneficial effects of healthy drink composed of seven chinese herb extract essences 医学検査 (共著)
51.	2012	論文	Molecular symmetry and biological activities of new symmetrical tris(2-aminoethyl) amine derivatives. Chem. Pharm. Bull. 60,408-414 (共著)
52.	2012/08	論文	Carbohydrate recognition of symmetrical tripodal receptor type tris (2-aminoethyl) amine derivatives J. Thermal. Anal. Calorim. (共著)
53.	2013	論文	Saponins esculeosides B-1 and B-2 in Italian canned tomatoes. Chem. Pharm. Bull.(Tokyo) (共著)
54.	2013	論文	Synthesis and biological evaluation of symmetrical 2,4,6-trisubstituted 1,3,5-triazine derivatives. Chem. Pharm. Bull.(Tokyo) (共著)
55.	2014/01	論文	Calysolins V-IX, resin glycosides from Calystegia soldanella and their antiviral activity toward herpes. Chem. Pharm. Bull.(Tokyo) (共著)
56.	2014/08	論文	7種漢方健康飲料の抗アレルギー剤としての可能性アレルギーの臨床 34 (8),47-52頁 (共著)
57.	2014/08	論文	Calysolins X-XIII, resin glycosides from Calystegia soldanella, and their antiviral activity toward herpes simplex virus. Chem Pharm Bull (Tokyo). (共著)
58.	2014/10	論文	Synthesis and antiviral activities of some 2,4,6-trisubstituted 1,3,5-triazines. Chem Pharm Bull (Tokyo). (共著)
59.	2015	論文	Effects of Lemon balm essential oil application on atopic dermatitis-like immune alteration in mice. International Journal of Phytomedicine 7 (1),46-54頁 (共著)
60.	2015	論文	Synthesis and Antiviral Evaluation of some C₃-Symmetrical Trialkoxy-substituted 1,3,5-Triazines and their Molecular Geometry Chem. Pharm. Bull. (共著)
61.	2015/05	論文	Antiviral Activity of Four New Resin Glycosides Calysolins XIV-XVII from Calystegia soldanella against Herpes Simplex Virus. Chem Pharm Bull. 63,641-648頁 (共著)
62.	2015/12	論文	7種漢方健康飲料の未病改善効果日本未病システム学会雑誌 21 (3) (共著)
63.	2016	論文	Novel Twin-drug Type C2-Symmetrical Phenylboronic Acid Pinacol Esters. Heterocycles 92,925-935頁 (共著)
64.	2016	論文	Preparation and Biological activity of Novel Twin-drug Type C2-Symmetrical Cyclic Phenylboronic Acid Derivatives. Heterocycles 95 (共著)
65.	2016/08	論文	Effects of lycium and lycium-composed formula on the peripheral coldness induced by local cooling in mice. Int. J. Phytomed. 8,353-359頁 (共著)
66.	2016/09	論文	Antiviral Activity and Molecular Geometry of Some New Symmetrical Tris(aminoalkyl)amine Derivatives Chem Pharm Bull (Tokyo) (共著)
67.	2017/01	論文	A new resin glycoside from Calystegia soldanella and its antiviral activity towards herpes. Nat Prod Res (共著)
68.	2017/01	論文	Anti-hyaluronidase Activity in Vitro and Amelioration of Mouse Experimental Dermatitis by Tomato Saponin, Esculeoside A. J Agric Food Chem 64 (2),403-408頁 (共著)
69.	2017/01	論文	Antiviral Activities of Some New 2,4,6-Trisubstituted 1,3,5-Triazines Having Alkoxy and/or Alkylamino Groups. Heterocycles (共著)
70.	2018	論文	Competitive Inhibition of Mammalian Hyaluronidase by Tomato Saponin, Esculeoside A. Nat Prod Comm 13 (11),1461-1463頁 (共著)
71.	2018	論文	Direct potentiation of capsaicin current by histamine and its effect by suplatast on rat trigeminal ganglia neurons. Pharmacology 102,37-41頁 (共著)
72.	2018	論文	Direct Potentiation of Capsaicin Current by Histamine and Its Effect by Suplatast on Rat Trigeminal Ganglia Neurons. Pharmacology 102,37-41頁 (共著)
73.	2018	論文	Preparation and Antiviral Activity of Some New C₃- and C_S-Symmetrical Tri-Substituted Triazine Derivatives Having Benzylamine Chemical & pharmaceutical bulletin 66 (8),830-838頁 (共著)
74.	2018	論文	Preparation　of　novel bivalent linker mode phenylboronic acid derivative　and their biological evaluation. Heterocycles. 96 (6),1088-1100頁 (共著)
75.	2018	論文	Tomato juice saponin, esculeoside B ameliorates mice experimental dermatitis. Functional Foods in Health and Disease. 8 (4),228-241頁 (共著)
76.	2018/01	論文	A new resin glycoside from Calystegia soldanella and its antiviral activity towards herpes. Nat Prod Res 31 (22),2660-2664頁 (共著)