Faculty Information - Komizu Yuuji

Komizu Yuuji

Department / Course FACULTY OF BIOTECHNOOLOGY AND LIFE SCIENCE Department of Biotechnology and Life Sciences

Job

Book and thesis
1.	2024/12	Papers	Enhanced Functionality of Human Hepatocytes using the Oxygen Permeable Culture Plate for Optimized Oxygen Supply in Co-culture Systems with Culture Inserts Alternatives to Animal Testing and Experimentation 29 (2),pp.64-75 (Co-authored)
2.	2024/05	Papers	Formation of functional, extended bile canaliculi, and increased bile acid production in sandwich-cultured human cryopreserved hepatocytes using commercially available culture medium Archives of Toxicology,pp.2605-2617 (Co-authored)
3.	2024/04	Papers	Selective elimination of tumorigenic cells from mixed culture of normal and tumorigenic cells using hybrid liposomes aimed at realizing of cell therapy. Cytotechnology 76 (2),pp.247-258 (Co-authored)
4.	2022/12	Papers	Consideration of Commercially Available Hepatocytes as Cell Sources for Liver-Microphysiological Systems by Comparing Liver Characteristics. Pharmaceutics 15 (1) (Co-authored)
5.	2021/08	Papers	Evaluation for Inhibitory Effects of Hybrid Liposomes on the Growth of Breast Cancer Stem Cells using Soft Agar Colony Formation Assay Alternatives to Animal Testing and Experimentation 26 (1),pp.1-8 (Co-authored)
6.	2020/12	Papers	Development of a New Culture Vessel using Hydrogen-rich Gelatin for Evaluation of Hydrogen Gas Effect on Cellular Toxicity Alternatives to Animal Testing and Experimentation 25 (2),pp.41-47 (Co-authored)
7.	2019/01	Papers	Inhibitory effect of hybrid liposomes on the growth of liver cancer stem cells Biochemical and Biophysical Research Communications 509 (1),pp.268-274 (Co-authored)
8.	2018/09	Papers	Evaluation of an In vitro Approach to the Prediction of In vivo Effects on Multidrug Resistance in Human Hepatoma Cells J Carcinog Mutagen 9 (2),pp.1000318 (Co-authored)
9.	2017/12	Papers	Maintenance of viability and functional expression of cryopreserved human hepatocytes using silicate fiber-based three-dimensional scaffold Alternatives to Animal Testing and Experimentation 22 (1),pp.101-106 (Co-authored)
10.	2017/01	Papers	Induction of drug resistance in human hepatoma cells cultured on a silicate fiber-based 3D scaffold Adv Biochem Biotechnol 112 (Co-authored)
11.	2016/08	Papers	Effects of macroporous hydroxyapatite carriers on the growth and function of human hepatoblasts derived from fetal hepatocytes J. Biosci. Bioeng. 122 (2),pp.240-245 (Co-authored)
12.	2015/12	Papers	Effects of the use of polyacrylnitrile nanofibers as 3D scaffolds on the growth and function of human hepatoblasts derived from fetal hepatocytes Alternatives to Animal Testing and Experimentation 20 (2),pp.66-72 (Co-authored)
13.	2015/07	Papers	Inhibitory Effects of Hybrid Liposomes on the Growth of Non-small Cell Lung Carcinoma Cells and Anti-invasive Activity by Ceramide Generation without any Drugs Journal of Carcinogenesis & Mutagenesis 6 (4),pp.1000230-1-5 (Co-authored)
14.	2015/02	Papers	Inhibition of HIV-1 entry by the tricyclic coumarin GUT-70 through the modification of membrane fluidity Biochem. Biophys. Res. Commun. 457 (3),pp.288-294 (Co-authored)
15.	2014/10	Papers	Hybrid Nanoparticles Inhibit Growth of Human Prostate Cancer Cells by Induction of Apoptosis SOJ Pharmacy & Pharmaceutical Sciences 1 (2),pp.1-4 (Co-authored)
16.	2014/09	Papers	Immunostimulation Effects of Powder from Barely-Shochu Distillation Remnants on a Human Natural Killer Cell Line in Vitro,pp.438-442 (Co-authored)
17.	2014/02	Papers	Cepharanthine inhibited HIV-1 cell-cell transmission and cell-free infection via modification of cell membrane fluidity Bioorg. Med. Chem. Lett. 24 (9),pp.2115-2117 (Co-authored)
18.	2014/01	Papers	Cell cycle arrest by hybrid liposomes for human lung carcinoma cells J. Carcinog. Mutagen. 5 (1),pp.1000157-1-6 (Co-authored)
19.	2013/07	Papers	Immunostimulatory effects of extract from nori (Porphyra yezoensis) in vitro and in vivo,pp.359-362 (Co-authored)
20.	2013/06	Papers	Hybrid liposomes inhibit tumor growth and lung metastasis of murine osteosarcoma cells Cancer Med. 2 (3),pp.267-276 (Co-authored)
21.	2012/11	Papers	Therapeutic effects of hybrid liposomes for mouse models of adult T-cell leukemia/ lymphoma in vivo Nano Bull. 1 (1),pp.120105-1-4 (Co-authored)
22.	2012/07	Papers	Residual powders from Shochu distillation remnants induce apoptosis in human hepatoma cells via the caspase-independent pathway J. Biosci. Bioeng. 114 (1),pp.104-109 (Co-authored)
23.	2012/06	Papers	Antimelanogenic and antioxidative effects of residual powders from Shochu distillation remnants Food Chem. 132 (4),pp.2140-2143 (Co-authored)
24.	2012/02	Papers	Selective accumulation and growth inhibition of hybrid liposomes to human hepatocellular carcinoma cells in relation to fluidity of plasma membranes Biochem. Biophys. Res. Commun. 418 (1),pp.81-86 (Co-authored)
25.	2012/02	Papers	Hybrid liposomes inhibit growth and invasion of human osteosarcoma cells leading to apoptosis Bioorg. Med. Chem. Lett. 22 (4),pp.1784-1787 (Co-authored)
26.	2012/02	Papers	Hybrid liposomes affect cellular lipid constituents and caveolae structures Bioorg. Med. Chem. Lett. 22 (4),pp.1731-1733 (Co-authored)
27.	2011/09	Papers	Remarkable inhibitory effects of hybrid liposomes on growth of human colon cancer cells through induction of cell cycle arrest along with apoptosis Int. J. Nanomed. 2011 (6),pp.1913-1920 (Co-authored)
28.	2011/07	Papers	Selective accumulation of hybrid liposomes into adult T-cell leukemia cells along with induction of apoptosis Bioorg. Med. Chem. Lett. 21 (13),pp.3962-3965 (Co-authored)
29.	2011/06	Papers	Therapeutic effects of hybrid liposomes composed of phosphatidylcholine and docosahexaenoic acid on the hepatic metastasis of colon carcinoma along with apoptosis in vivo Biol. Pharm. Bull. 34 (6),pp.901-905 (Co-authored)
30.	2011/05	Papers	Inhibitory effects of extracts from Citrus unshiu Marc. encapsulated in hybrid liposomes on the growth of tumor cells in vitro,pp.271-276 (Co-authored)
31.	2011/04	Papers	Experimental therapeutic effects of hybrid liposomes on the alzheimer's disease in vitro,pp.775-782 (Co-authored)
32.	2011/04	Papers	Therapeutic effects of Ca²⁺ on peritoneal dissemination of gastric carcinoma in vivo J. Health Sci. 57 (2),pp.210-214 (Co-authored)
33.	2011/04	Papers	Membrane-targeted nanotherapy with hybrid liposomes for tumor cells leading to apoptosis ACS Med. Chem. Lett. 2 (4),pp.275-279 (Co-authored)
34.	2011/03	Papers	Specific interaction between Ca²⁺and anionic lipids in cancer cells along with apoptosis Biol. Pharm. Bull. 34 (3),pp.439-442 (Co-authored)
35.	2011/01	Papers	Inhibitory effects of hybrid liposomes composed of phosphatidylcholine and docosahexaenoic acid on the growth of colon cancer cells along with apoptosis and differentiation Chem. Lett. 40 (1),pp.90-92 (Co-authored)
36.	2010/12	Papers	Clustering of lipid rafts in plasma membranes by hybrid liposomes for leukemia cells along with apoptosis Chem. Lett. 39 (12),pp.1291-1293 (Co-authored)
37.	2010/11	Papers	Specific accumulation and antitumor effects of hybrid liposomes on the growth of lung tumor cells,pp.1581-1587 (Co-authored)
38.	2010/06	Papers	Hybrid liposomes inhibit the growth of primary effusion lymphoma in vitro and in vivo Leuk. Res. 34 (7),pp.906-911 (Co-authored)
39.	2010/06	Papers	Hybrid liposomes inhibit the growth of Cholangiocarcinoma by induction of cell cycle arrest in G1 phase Bioorg. Med. Chem. Lett. 20 (12),pp.3680-3682 (Co-authored)
40.	2008/08	Papers	Selective inhibitory effects of hybrid liposomes on the growth of HIV type 1-infected cells in vitro Bioorg. Med. Chem. Lett. 8 (16),pp.4578-4580 (Co-authored)
41.	2008/06	Papers	Antitumor and immunostimulatory effects of residual powder from barley-Shochu distillation remnants J. Health Sci. 54 (3),pp.287-293 (Co-authored)
42.	2007/02	Papers	Whitening effect of shochu distillation remnants: Inhibitory effects on the production of melanins and tyrosinase activity KAGAKU KOGAKU RONBUNSHU (Japanese),pp.168-172 (Co-authored)
43.	2007/02	Papers	Remarkable immunostimulation effects of hybrid liposomes on human peripheral blood mononuclear cells in vitro Bioorg. Med. Chem. Lett. 17 (3),pp.613-616 (Co-authored)
44.	2006/11	Papers	Membrane targeted chemotherapy with hybrid liposomes for colon tumor cells leading to apoptosis Bioorg. Med. Chem. Lett. 16 (23),pp.6131-6134 (Co-authored)
45.	2014/02	Papers	Cancer Chemotherapy with Hybrid Liposomes and Its Molecular Mechanism,pp.5-10 (Co-authored)
46.	2016/01	Books	Membrane-Targeted Nanotherapy with Hybrid Liposomes for Cancer Cells Leading to Apoptosis Molecular Science of Fluctuations Toward Biological Functions,pp.221-244 (Co-authored)
47.	2010/03	Papers	Highly selective fusion and accumulation of hybrid liposomes into primary effusion lymphoma cells along with induction of apoptosis Biochem. Biophys. Res. Commun. 393 (3),pp.445-448 (Co-authored)
48.	2008/10	Papers	Inhibitory effects of hybrid liposomes on the growth of gastric tumor cells established from cotton rats,pp.1485-1492 (Co-authored)