教員情報 - 千々岩　崇仁

チヂワ　タカヒト Chijiwa Takahito
千々岩　崇仁

所属生物生命学部生物生命学科

職種教授

著書・論文歴
1.	2020/05	論文	Immunohistochemical pharmacokinetics of the anti-diabetes drug Alogliptin in rat kidney and liver. Acta Histochem. Cytochem. 53 (3),doi: 10.1267/ahc. 19036 (共著)
2.	2020/03	論文	Discovery of the gene encoding a novel Small Serum Protein (SSP) of Protobothrops flavoviridis and the evolution of SSPs. Toxins 12 (3),177 (共著)
3.	2019/10	論文	Alternative mRNA Splicing in Three Venom Families Underlying a Possible Production of Divergent Venom Proteins of the Habu Snake, Protobothrops flavoviridis. Toxins 11,doi: 10.3390/toxins11100581. (共著)
4.	2019/07	論文	unique structure (construction and configuration) and evolution of the array of small serum protein genes of P. rotobothrops flavoviridis snake Bioscience Reports 39 (7),10.1042/BSR20190560 (共著)
5.	2018	論文	The habu genome reveals accelerated evolution of venom protein genes SCIENTIFIC REPORTS DOI:10.1038/s41598-018-28749-4 (共著)
6.	2016	論文	The taxonomic position and the unexpected divergence of the Habu viper, Protobothrops among Japanese subtropical islands. (101),91-100頁 (共著)
7.	2105	論文	Interisland variegation of venom [Lys(49)]phospholipase A2 isozyme genes in Protobothrops genus snakes in the southwestern islands of Japan. Toxicon (107),210-216頁 (共著)
8.	2014	論文	The finding of a group IIE phospholipase A2 gene in a specified segment of Protobothrops flavoviridis genome and its possible evolutionary relationship to group IIA phospholipase A2 genes. 6,3471-3487頁 (共著)
9.	2014	論文	Epithelium specific ETS transcription factor, ESE-3, of Protobothrops flavoviridis snake venom gland transactivates the promoters of venom phospholipase A2 isozyme genes. Toxicon 92,133-139頁 (共著)
10.	2014	論文	Discovery of a novel vascular endothelial growth factor (VEGF) with no affinity to heparin in Gloydius tsushimaensis venom Toxicon 86,107-115頁 (共著)
11.	2013/03	論文	Allopatry of Protobothrops flavoviridis (Viperidae, Crotalinae) venom proteins between Okinawa islands and its outlying small islands, Iheyajima and Kumejima The Biological Magazine Okinawa 51, 17-25 75,480-488 (共著)
12.	2013	論文	Suppression of severe lesions, myonecrosis and hemorrhage, caused by Protobothrops flavoviridis venom with its serum proteins. 76,197-205頁 (共著)
13.	2013	論文	Structural characteristics and evolution of the Protobothrops elegans pancreatic phospholipase A2 gene in contrast with those of Protobothrops genus venom phospholipase A2 Genes Biosci Biotechnol Biochem,77: 97-102 75,864-870 (共著)
14.	2013	論文	Structural characteristics and evolution of a novel venom phospholipase A2 gene from Protobothrops flavoviridis Biosci Biotechnol Biochem, 76: 551-558 461,15-25 (共著)
15.	2011/03	論文	A [Lys49]phopholipase A2 from Protobothrops flavoviridis venom induces caspase-independent apoptotic cell death accompanied by rapid plasma-membrane rupture in human leukemia cells Biosci Biotechnol Biochem, 75: 864-870 75,864-870 (共著)
16.	2011	論文	Identification and evolution of venom phospholipase A2 inhibitors from Protobothrops elegans Biosci Biotechnol Biochem, 75: 480-488 75,480-488 (共著)
17.	2010	論文	Unique structural characteristics and evolution of a cluster of venom phospholipase A(2) isozyme genes of Protobothrops flavoviridis snake Gene, 461: 15-25 461,15-25 (共著)
18.	2009	論文	Island specific expression of a novel [Lys(49)]phospholipase A(2) (BPIII) in Protobothrops flavoviridis venom in Amami-Oshima, Japan. Toxicon, 54: 399-407 54,399-407 (共著)
19.	2008	論文	Molecular cloning and characterization of the repetitive DNA sequences that comprise the constitutive heterochromatin of the A and B chromosomes of the Korean field mouse (Apodemus peninsulae, Muridae, Rodentia). Chromosome Res., 16: 1013-1026 16,1013-1026 (共著)
20.	2008	論文	Identification of the B subtype of gamma-phospholipase A2 inhibitor from Protobothrops flavoviridis serum and molecular evolution of snake serum phospholipase A2 inhibitors. J Mol Evol, 66: 298-307 66,298-307 (共著)
21.	2008	論文	A novel recombinant system for functional expression of myonecrotic snake phospholipase A2 in Escherichia coli using a new fusion affinity tag Protein Expr Purif, 58: 194-202 58,194-202 (共著)
22.	2006	論文	Discovery of novel [Arg49]phospholipase A2 isozymes from Protobothrops elegans venom and regional evolution of Crotalinae snake venom phospholipase A2 isozymes in the southwestern islands of Japan and Taiwan. Toxicon, 48: 672-682 48,672-682 (共著)
23.	2005	論文	Purification, primary structures and evolution of coagulant proteases from Deinagkistrodon actus venom Toxicon, 46: 907-917 (共著)
24.	2005	論文	Amino acid sequence of a basic aspartate-49-phospholipase A2 from Trimeresurus flavoviridis venom and phylogenetic analysis of Crotalinae venom phospholipases A2 Toxicon, 46: 185-195 (共著)
25.	2003	論文	Interisland mutation of a novel phospholipase A2 from Trimeresurus flavoviridis venom and evolution of Crotalinae group II phospholipase A2 J Mol Evol, 57: 546-554 (共著)
26.	2003	論文	Interisland evolution of Trimeresurus flavoviridis venom phospholipase A2 isozymes J Mol Evol, 56: 286-293 (共著)
27.	2002	論文	Three novel DNMT3B in Japanese patients with ICF syndrome American J Med, 112: 31-37 (共著)
28.	2002	論文	Skeletal muscle necrosis in rat induced by Trimeresurus flavoviridis venom can be prevented by its serum proteins South Pacific Study, 23: 11-18 (共著)
29.	2002	論文	Characterization, primary structure and molecular evolution of anticoagulant protein from Agkistrodon actus venom Toxicon, 40: 803-813 (共著)
30.	2001	論文	Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia. BLOOD 97, 1172-1179 (共著)
31.	2001	論文	Enzymatic properties of de novo-type mouse DNA (cytosine-5) methyltransferases. Nucleic Acids Res., 29: 3506-3512 (共著)
32.	2001	論文	Characterization, amino acid sequence and evolution of edema-inducing, basic phospholipase A2 from Trimeresurus flavoviridis venom. Toxicon 39, 1069-1076 (共著)
33.	2000	論文	Regional evolution of venom-gland phospholipase A2 isoenzymes of Trimeresurus flavoviridis snakes in the southwestern islands of Japan. Biochem J. 15, 491-499 (共著)
34.	2000	論文	Regional and accelerated molecular evolution in group I snake venom gland phospholipase A2 isozymes. Toxicon 38, 449-462 (共著)
35.	1999	論文	Atmospheric deposition of 35S. J. Radioanal. Nucl. Chem. (共著)
36.	1998	論文	Retrotransposable CR1-like elements in crotalinae snake genomes. Toxicon 36, 915-920 (共著)
37.	1997	論文	Structures of genes encoding phospholipase A2 inhibitors from the serum of Trimeresurus flavoviridis snake. Gene 191, 31-37 (共著)
38.	1997	論文	Lys-49-phospholipases A2 as active enzyme for beta-arachidonoyl phospholipid bilayer membranes. Biochem. Mol. Biol. Int. 43, 19-26 (共著)
39.	1996	論文	Accelerated evolution of Crotalinae snake venom gland serine proteases. FEBS Lett. 397, 83-88 (共著)
40.	2013	論文	トロンビン受容体PAR1の立体構造日本血栓止血学会誌, 24 (4), 454-459 (共著)
41.	2005	論文	Molecular diversity and accelerated evolution of C-type lectin-like proteins from snake venom Toxicon, 45: 1-14 45,1-14 (共著)
42.	2004	論文	ハブ毒を科学する化学と生物 42,687-693 (共著)
43.	2002	著書	Accelerated and regional evolution of snake venom gland isozymes. In: Perspectives in Molecular Toxinology,387-400 (共著)
44.	2003	論文	Molecular evolution of myotoxic phospholipase A2 from snake venom. Toxicon, 42: 841-854 (共著)