Faculty Information - Gotou Kouichi

Gotou Kouichi

Department / Course FACULTY OF BIOTECHNOOLOGY AND LIFE SCIENCE Department of Biotechnology and Life Sciences

Job

Book and thesis
1.	2026/02	Papers	Enhanced Therapeutic Efficacy of Photodynamic Therapy Using Hybrid Liposomes Containing Indocyanine Green in a Triple-Negative Breast Cancer Mouse Model 49,pp.310-315 (Co-authored)
2.	2025/12	Papers	Hybrid Liposomes of Nanoparticles Achieve Targeted Accumulation and Induce Apoptosis in TE-4 Esophageal Cancer Cells without Antitumor Drugs 16,pp.1000490(1)-1000490(8) (Co-authored)
3.	2024/06	Papers	Induction of antigen-specific immunity by mesoporous silica nanoparticles incorporating antigen peptides 138,pp.254-260 (Co-authored)
4.	2024/02	Papers	Efficacy of Cationic Hybrid Liposomes Composed of L-α-Dimyristoylphosphatidylcholine in Targeting Negatively Charged Cholangiocarcinoma Cell Membranes Without Any Drug In Vitro and In Vivo Journal of Carcinogenesis & Mutagenesis 15,pp.1000460(1)-1000460(5) (Co-authored)
5.	2021/09	Papers	“Dried Seaweed (Porphyra yezoensis) Extract Promotes Fat Metabolism in Fatty Liver Cell and Mouse Models Journal of Food & Nutritional Disorders 10,pp.1000309(1)-1000309(5) (Co-authored)
6.	2020/01	Papers	Cancer Therapeutic and Preventive Effects of Dried Seaweed (Porphyra yezoensis) Extract by Gut Immunity Activation 9,pp.1000270(1)-1000270(6) (Co-authored)
7.	2015/09	Papers	Nanoformulation of Geranylgeranyltransferase-I Inhibitors for Cancer Therapy: Liposomal Encapsulation and pH-Dependent Delivery to Cancer Cells PLOS ONE 10,pp.e0137595(1)-e0137595(17) (Co-authored)
8.	2012/07	Papers	Residual powders from Shochu distillation remnants induce apoptosis in human hepatoma cells via the caspase-independent pathway Journal of Bioscience and Bioengineering 114 (1),pp.104-109 (Co-authored)
9.	2012/06	Papers	Anticancer effects of residual powder from barley-Shochu dstillation remnants against the orthotopic xenograft mouse models of hepatocellular carcinoma in vivo Biological & Pharmaceutical Bulletin 35 (6),pp.984-987 (Co-authored)
10.	2012/03	Papers	Antimelanogenic and antioxidative effects of residual powders from Shochu distillation remnants Food Chemistry 132,pp.2140-2143 (Co-authored)
11.	2011/09	Papers	Remarkable inhibitory effects of hybrid liposomes on growth of human colon cancer cells through induction of cell cycle arrest along with apoptosis International Journal of Nanomedicine 6,pp.1913-1920 (Co-authored)
12.	2011/07	Papers	Selective accumulation of hybrid liposomes into adult T-cell leukemia cells along with induction of apoptosis Bioorganic & Medicinal Chemistry Letters 21,pp.3962-3965 (Co-authored)
13.	2011/06	Papers	Therapeutic effects of hybrid liposomes composed of phosphatidylcholine and docosahexaenoic acid on the hepatic metastasis of colon carcinoma along with apoptosis in vivo Biological & Pharmaceutical Bulletin 34 (6),pp.901-905 (Co-authored)
14.	2011/06	Papers	Membrane targeted chemotherapy with hybrid liposomes for tumor cells leading to apoptosis Current Pharmaceutical Designs 17 (17),pp.1709-1719 (Co-authored)
15.	2011/05	Papers	Effective drug delivery system for duchenne muscular dystrophy using hybrid liposomes including gentamicin along with reduced toxicity Biological & Pharmaceutical Bulletin 34 (5),pp.712-716 (Co-authored)
16.	2011/04	Papers	Therapeutic effects of Ca2+ on peritoneal dissemination of gastric carcinoma in vivo Journal of Health Science 57 (2),pp.210-214 (Co-authored)
17.	2011/04	Papers	Membrane-targeted nanotherapy with hybrid liposomes for tumor cells leading to apoptosis ACS Medicinal Chemistry Letters 2,pp.275-279 (Co-authored)
18.	2011/03	Papers	Specific interaction between Ca2+ and anionic lipids in cancer cells along with apoptosis Biological & Pharmaceutical Bulletin 34 (3),pp.439-442 (Co-authored)
19.	2011/01	Papers	Inhibitory effects of hybrid liposomes composed of phosphatidylcholine and docosahexaenoic acid on the growth of colon cancer cells along with apoptosis and differentiation Chemistry Letters 40 (1),pp.91-92 (Co-authored)
20.	2010/12	Papers	Clustering of lipid rafts in plasma membranes by hybrid liposomes for leukemia cells along with apoptosis Chemistry Letters 39 (12),pp.1291-1293 (Co-authored)
21.	2008/07	Papers	Remarkably High Inhibitory Effects of Docosahexaenoic Acid Incorporated into Hybird Liposomes on the Growth of Tumor Cells along with Apoptosis International Journal of Pharmaceutics 359,pp.264-271 (Co-authored)
22.	2008/06	Papers	Antitumor and Immunostimulatory Effects of Residual Powder from Barley-Shochu Distillation Remnants Journal of Health Science 54 (3),pp.287-293 (Co-authored)
23.	2008/03	Papers	Induction of Apoptosis of Human Tumor Cells by Hybird Liposomes Including Docosahexaenoic Acid Bioorganic & Medicinal Chemistry Letters 18,pp.1880-1883 (Co-authored)
24.	2008/01	Papers	Specific fixed aqueous layer of three-component hybrid liposomes related to inhibition of hepatoma cells growth Chemistry Letters 37 (1),pp.118-119 (Co-authored)
25.	2007/02	Papers	Remarkable immunostimulation effects of hybrid liposomes on human peripheral blood mononuclear cells in vitro Bioorganic & Medicinal Chemistry Letters 17 (3),pp.613-616 (Co-authored)
26.	2005/03	Papers	Marked iinhibitory effects of extracts from barley-koji miso encapsulated in hybrid liposomes on the growth of human stomach tumor cells in vitro Chemistry Letters 34 (3),pp.370-371 (Co-authored)
27.	2004/09	Papers	Inhibitory effects of extracts from peels of Citrus natsudaidai encapsulated in hybrid liposomes on the growth of tumor cells in vitro Biological & Pharmaceutical Bulletin 27 (9),pp.1465-1467 (Co-authored)
28.	2004/01	Papers	Enzymatic and hyperglycemia stability of chemically modified insulins with hydrophobic acyl groups Bioorganic & Medicinal Chemistry Letters 14,pp.481-483 (Co-authored)
29.	2003/02	Papers	Steric-control for the enantioselective hydrolysis of amino acid esters in hybrid membrane systems Chemical & Pharmaceutical Bulletin 51 (2),pp.224-226 (Co-authored)
30.	2003/02	Papers	Fairly marked enantioselectivity for the hydrolysis of amino acid esters by chemically modified enzymes The Journal of Organic Chemistry 68 (4),pp.1314-1318 (Co-authored)
31.	2003/02	Papers	Catalytic specificity exhibited by p-sulfonatocalix[n]arenes in the methanolysis of N-Ac-L-amino acids The Journal of Organic Chemistry 68 (3),pp.865-870 (Co-authored)
32.	2002/09	Papers	Cyclodexitrin- mediated deacylation of amino acid esters with marked stereoselectivity Chemical & Pharmaceutical Bulletin 50 (9),pp.1283-1285 (Co-authored)
33.	2002/04	Papers	Remarkably enhanced inhibitory effects of three-component hybrid liposomes including sugar surfactants on the growth of lung carcinoma cells Chemical & Pharmaceutical Bulletin 50 (4),pp.563-565 (Co-authored)
34.	2001/03	Papers	Catalytic specificity of p-sulfonato- calix[n]arenes on the alcoholysis of N-Ac-L-amino acids in methanol solution Journal of Molecular Catalysis B: Enzymatic 11,pp.985-989 (Co-authored)
35.	1999/05	Papers	Steric-control for the enantioselective hydrolysis of amino acid esters with membrane-bound enzyme models Tetrahedron Letters 40 (11),pp.2129-2132 (Co-authored)
36.	1999/01	Papers	Diastereoselective specificity for the hydrolysis of dipeptide esters in aqueous media Chemistry Letters,pp.73-74 (Co-authored)
37.	1996/05	Papers	A remarkably enhanced diastereoselectivity for the hydrolysis of dipeptide esters responding to pH and temperature in buffer solutions Tetrahedron Letters 37 (20),pp.3461-3464 (Co-authored)
38.	1995/06	Papers	Hybrid liposomes coupled to steric control with high enantioselectivity The Journal of Organic Chemistry 60 (11),pp.3342-3346 (Co-authored)
39.	1994/11	Papers	Remarkable salt enantioselective hydrolysis of amino acidesters with the active tripeptide in vesicular systems Chemistry Letters,pp.2081-2084 (Co-authored)
40.	1990/09	Papers	Remarkable substituent effects on the micellar enantioselective hydrolysis of amino acid esters. Tetrahedron Letters 31 (37),pp.5311-5314 (Co-authored)
41.	1990/09	Papers	A remarkable steric control for the enantioselective hydrolytic-cleavage of amino acid esters responding to ionic strength Tetrahedron Letters 31 (37),pp.5335-5338 (Co-authored)