Faculty Information - Murase Hirotaka | SOJO UNIVERSITY

（Last updated : 2024-04-09 11:28:22）

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Murase Hirotaka

Department / Course FACULTY OF PHARMACEUTICAL SCIENCES Department of Pharmaceutical Sciences

Job

Book and thesis
1.	2024/02	Papers	Development of PCR primers enabling the design of flexible sticky ends for efficient concatenation of long DNA fragments, RSC Chemical Biology, 5,pp.360-371 (Co-authored)
2.	2023/06	Papers	The Effect of γ Phosphate Modified Deoxynucleotide Substrates on PCR Activity and Fidelity, ChemBioChem, 24, e202200572 (Co-authored)
3.	2023/05	Papers	Cap analogs with a hydrophobic photocleavable tag enable facile purification of fully capped mRNA with various cap structures, Nature Communications, 14, 2657 (Co-authored)
4.	2023/01	Papers	Site-Specific Tritium Labeling at the Predefined Internal Position of the Chemically-Modified RNA, Chemical and Pharmaceutical Bulletin, 71,pp.64-69 (Co-authored)
5.	2022/03	Papers	Development of a selective ligand for G–G mismatches of CGG repeat RNA inducing the RNA structural conversion from the G-quadruplex into a hairpin-like structure, Organic & Biomolecular Chemistry, 20,pp.3375-3381 (Co-authored)
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Academic conference presentation
1.	2023/11	Development of a new oligonucleotide agent for site-specific RNA acetylation (The 50th International Symposium on Nucleic Acids Chemistry (ISNAC2023))
2.	2023/07	Read-through of the premature-termination codon (PTC) based on the site-specific chemical modifications of mRNA (日本核酸医薬学会第8回年会)
3.	2022/11	Development of a small-molecule inducer that converts the G-quadruplex structure of CGG repetitive RNA to a hairpin form (The 49th International Symposium on Nucleic Acids Chemistry (ISNAC2022))
4.	2015/12	Selective and cooperative binding of small molecular ligands to a GC repetitive site of DNA mediated by multiple complexation with metal cations (Pacifichem 2015)
5.	2017/12	The development of small molecules binding to the hairpin RNA structure (The 2nd International Symposium on Biofunctional Chemistry)
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Academic background
1.	2008/04～2012/03	Faculty of Pharmaceutical Science Kyushu University Graduated
2.	2012/04～2014/03	Master Graduate School, Division of Pharmaceutical Sciences Kyushu University Finished
3.	2014/04～2017/03	Doctorial Graduate School, Division of Pharmaceutical Sciences Kyushu University Finished Ph.D.

Business career
1.	2017/04 ～ 2018/12	Research Assistant Professor Tohoku University Institute of Multidisciplinary Research for Advanced Materials
2.	2019/01 ～ 2020/05	Postdoc / Research Assistant Professor Nagoya University Graduate School, Division of Pharmaceutical Sciences
3.	2020/06 ～ 2023/03	Postdoc / Research Assistant Professor Nagasaki International University Faculty of Pharmaceutical Science
4.	2023/04/01 ～	SOJO UNIVERSITY FACULTY OF PHARMACEUTICAL SCIENCES Department of Pharmaceutical Sciences

researchmap Researcher code
R000050135

E-Mail Address

Research Field
1.	2018/11	The 45th international Symposium on Nucleic Acids Chemistry ISNAC Outstanding Oral Presentation Award for Young Scientist (Ohtsuka Award)

Present specialized field
Life sciences / Pharmaceuticals - chemistry and drug development, Life sciences / Bioorganic chemistry keyword(Organic Chemistry, Nucleic Acids Chemistry)

Department laboratory expense researcher number
10814486