Faculty Information - Murase Hirotaka | SOJO UNIVERSITY

（Last updated : 2025-05-19 10:42:19）

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Murase Hirotaka

Department / Course FACULTY OF PHARMACEUTICAL SCIENCES Department of Pharmaceutical Sciences

Job

Book and thesis
1.	2025	Papers	New Nucleoside Derivatives for Hybridization-Assisted Catalysis of Site-Selective Acetylation of 2'-OH of RNA, Chemical and Pharmaceutical Bulletin, 2025, 73, 457-466 (Co-authored)
2.	2025	Papers	Crystallographic analysis of G-clamp–RNA complex assisted by large scale RNA-binding profile, Chemical Communications, 2025, 61, 1120-1123 (Co-authored)
3.	2024	Papers	Site-specific acetyl modification of 2'-OH of RNA by an oligonucleotide acetylating reagent, Chemical Communications, 2024, 60, 13440–13442 (Co-authored)
4.	2024	Papers	Development of hydrophobic tag purifying monophosphorylated RNA for chemical synthesis of capped mRNA and enzymatic synthesis of circular mRNA, Nucleic Acids Research, 2024, 52, 12141–12157 (Co-authored)
5.	2024	Papers	Synthesis of 2'-formamidonucleoside phosphoramidites for suppressing the seed-based off-target effects of siRNAs, Nucleic Acids Research, 2024, 52, 10754-10774 (Co-authored)
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Academic conference presentation
1.	2023/11	Development of a new oligonucleotide agent for site-specific RNA acetylation (The 50th International Symposium on Nucleic Acids Chemistry (ISNAC2023))
2.	2023/07	Read-through of the premature-termination codon (PTC) based on the site-specific chemical modifications of mRNA (日本核酸医薬学会第8回年会)
3.	2022/11	Development of a small-molecule inducer that converts the G-quadruplex structure of CGG repetitive RNA to a hairpin form (The 49th International Symposium on Nucleic Acids Chemistry (ISNAC2022))
4.	2022/11	Simple and Efficient Method for Site-selective Internal Tritium Labeling of Chemically Modified Oligonucleotides (The 49th International Symposium on Nucleic Acids Chemistry (ISNAC2022))
5.	2021/08	Development of the small molecular binder for the r(CGG) repeat (IS3NA-IRT Virtual Symposium 2021)
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Academic background
1.	2008/04～2012/03	Faculty of Pharmaceutical Science Kyushu University Graduated
2.	2012/04～2014/03	Master Graduate School, Division of Pharmaceutical Sciences Kyushu University Finished
3.	2014/04～2017/03	Doctorial Graduate School, Division of Pharmaceutical Sciences Kyushu University Finished Ph.D.

Business career
1.	2017/04 ～ 2018/12	Research Assistant Professor Tohoku University Institute of Multidisciplinary Research for Advanced Materials
2.	2019/01 ～ 2020/05	Postdoc / Research Assistant Professor Nagoya University Graduate School, Division of Pharmaceutical Sciences
3.	2020/06 ～ 2023/03	Postdoc / Research Assistant Professor Nagasaki International University Faculty of Pharmaceutical Science
4.	2023/04/01 ～	SOJO UNIVERSITY FACULTY OF PHARMACEUTICAL SCIENCES Department of Pharmaceutical Sciences

researchmap Researcher code
R000050135

E-Mail Address

Research Field
1.	2018/11	The 45th international Symposium on Nucleic Acids Chemistry ISNAC Outstanding Oral Presentation Award for Young Scientist (Ohtsuka Award)

Present specialized field
Life sciences / Pharmaceuticals - chemistry and drug development, Synthetic organic chemistry, Bioorganic chemistry keyword(Nucleic Acids Chemistry)

Department laboratory expense researcher number
10814486