Faculty Information - Murase Hirotaka | SOJO UNIVERSITY

（Last updated : 2024-08-30 16:02:25）

Visruth.jpg not found

Murase Hirotaka

Department / Course FACULTY OF PHARMACEUTICAL SCIENCES Department of Pharmaceutical Sciences

Job

Book and thesis
1.	2024/08	Papers	The selective chemical modification of the 6-amino group of adenosine of the premature termination codon induces readthrough to produce full-length peptide in the reconstituted E. Coli translation system, Bioorganic & Medicinal Chemistry, 111,pp.117868 (Co-authored)
2.	2024/07	Papers	2'-β-Methylselenyl nucleos(t)ide analogs as reverse transcriptase inhibitors against diverse HIV mutants, Bioorganic & Medicinal Chemistry 110,pp.117813 (Co-authored)
3.	2024/05	Papers	Large-scale analysis of small molecule-RNA interactions using multiplexed RNA structure libraries, Communications Chemistry, 7, 98 (Co-authored)
4.	2024/04	Papers	Manipulating nucleic acids-regulation of gene expression through higher order structure and chemical modification,pp.53-62 (Co-authored)
5.	2024/02	Papers	Development of PCR primers enabling the design of flexible sticky ends for efficient concatenation of long DNA fragments, RSC Chemical Biology, 5,pp.360-371 (Co-authored)
Display All（15）

Academic conference presentation
1.	2023/11	Development of a new oligonucleotide agent for site-specific RNA acetylation (The 50th International Symposium on Nucleic Acids Chemistry (ISNAC2023))
2.	2023/07	Read-through of the premature-termination codon (PTC) based on the site-specific chemical modifications of mRNA (日本核酸医薬学会第8回年会)
3.	2022/11	Development of a small-molecule inducer that converts the G-quadruplex structure of CGG repetitive RNA to a hairpin form (The 49th International Symposium on Nucleic Acids Chemistry (ISNAC2022))
4.	2015/12	Selective and cooperative binding of small molecular ligands to a GC repetitive site of DNA mediated by multiple complexation with metal cations (Pacifichem 2015)
5.	2017/12	The development of small molecules binding to the hairpin RNA structure (The 2nd International Symposium on Biofunctional Chemistry)
Display All（21）

Academic background
1.	2008/04～2012/03	Faculty of Pharmaceutical Science Kyushu University Graduated
2.	2012/04～2014/03	Master Graduate School, Division of Pharmaceutical Sciences Kyushu University Finished
3.	2014/04～2017/03	Doctorial Graduate School, Division of Pharmaceutical Sciences Kyushu University Finished Ph.D.

Business career
1.	2017/04 ～ 2018/12	Research Assistant Professor Tohoku University Institute of Multidisciplinary Research for Advanced Materials
2.	2019/01 ～ 2020/05	Postdoc / Research Assistant Professor Nagoya University Graduate School, Division of Pharmaceutical Sciences
3.	2020/06 ～ 2023/03	Postdoc / Research Assistant Professor Nagasaki International University Faculty of Pharmaceutical Science
4.	2023/04/01 ～	SOJO UNIVERSITY FACULTY OF PHARMACEUTICAL SCIENCES Department of Pharmaceutical Sciences

researchmap Researcher code
R000050135

E-Mail Address

Research Field
1.	2018/11	The 45th international Symposium on Nucleic Acids Chemistry ISNAC Outstanding Oral Presentation Award for Young Scientist (Ohtsuka Award)

Present specialized field
Life sciences / Pharmaceuticals - chemistry and drug development, Life sciences / Bioorganic chemistry keyword(Organic Chemistry, Nucleic Acids Chemistry)

Department laboratory expense researcher number
10814486