Faculty Information - LIU Xiaohui | SOJO UNIVERSITY

（Last updated : 2025-11-09 22:18:28）

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LIU Xiaohui

Department / Course FACULTY OF BIOTECHNOOLOGY AND LIFE SCIENCE Department of Biotechnology and Life Sciences

Job

Book and thesis
1.	2024/10/21	Papers	The N-terminal activation function AF-1 domain of ERα interacts directly with the C-terminal AF-2-holding ligand-binding domain to recruit the coactivator proteins PLOS ONE 19 ((10)),pp.e0312276 (Co-authored)
2.	2021/04	Papers	ERα-agonist and ERβ-antagonist bifunctional next-generation bisphenols with no halogens: BPAP, BPB, and BPZ Toxicology Letters 345,pp.24-33 (Co-authored)
3.	2021/02	Papers	Bisphenol-C is the strongest bifunctional ERα-agonist and ERβ-antagonist due to magnified halogen bonding PLOS ONE 16 (2),pp.e0246583 (Co-authored)
4.	2020/02	Papers	Evaluation of the influence of halogenation on the binding of bisphenol A to the estrogen-related receptor γ Chemical Research in Toxicology 33 (4),pp.889-902 (Co-authored)
5.	2019/12	Papers	Bisphenol AF: Halogen bonding is a major driving force for the dual ERα-agonist and ERβ-antagonist activities Bioorganic & Medicinal Chemistry 28 (3),pp.115274 (Co-authored)
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Academic conference presentation
1.	2025/11/03	Subtype-specific regulatory mechanism mediated through the N-terminal domain in activation of estrogen receptor ERα for the next-generation bisphenols
2.	2025/10/21	N-terminal domain of estrogen receptor α regulates a subtype-specific agonist/antagonist mechanism for next-generation bisphenols (The 62nd Japanese Peptide Symposium)
3.	2024/11/06	The N-terminal activation function 1 (AF-1) adjacent to the C-terminal AF-2 interacts directly with each other in wild-type ERα to recruit the coactivator proteins
4.	2024/11/08	Elucidation of the mechanism of androgen receptor transcriptional activity suppression mediated by ERRγ in prostate cancer cells
5.	2024/08/27	Ecological survey Sitophilus oryzae and Sitophilus zeamais in Japan (第27回国際昆虫学会議（ICE2024）)
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Academic background
1.	2003/04～2005/03	Master Graduate School, Division of Natural Science Kyushu University Finished
2.	2005/04～2008/03	Doctorial Graduate School, Division of Natural Science Kyushu University Finished

Business career
1.	2013/04 ～ 2019/03	Assistant Professor
2.	2019/04/01 ～	Graduate School of Engineering /(DC)Division of Applied Microbial Technology
3.	2019/04/01 ～	Graduate School of Engineering /Division of Applied Microbial Technology
4.	2019/04/01 ～	SOJO UNIVERSITY FACULTY OF BIOTECHNOOLOGY AND LIFE SCIENCE Department of Applied Microbial Technology

researchmap Researcher code
B000321189

E-Mail Address

Research Field
1.	2013/11	日本ペプチド学会 APIPS2013[第4回アジア-太平洋国際ペプチドシンポジウム4th APIPS/第50回ペプチド討論会]優秀ポスター賞 (Constitutive α-helix-peptides required for functional dimerization of estrogen-related receptor γ (ERRγ))
2.	2011/07	日本生化学会平成23年度日本生化学会-欧文誌JB (Journal of Biochemistry) 論文賞 (istinction of the binding modes for human nuclear receptor ERRγ between bisphenol A and 4-hydroxytamoxifen.)

Present specialized field
Chemical substance influence on environment, Others, Molecular biology, Functional biochemistry

Department laboratory expense researcher number
60596849